Invention Grant
- Patent Title: Enzyme assays on a droplet actuator
- Patent Title (中): 液滴致动器上的酶测定
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Application No.: US14644989Application Date: 2015-03-11
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Publication No.: US09574220B2Publication Date: 2017-02-21
- Inventor: Allen E Eckhardt , Carrie Graham , Ramakrishna Sista , Vamsee K. Pamula , Theodore Winger , Tong Wang , Yalin Xiong , Ning Wu , Sanjay Saha , Gajendrasinh Raolji , Raveendra Dayam
- Applicant: Advanced Liquid Logic, Inc.
- Applicant Address: US CA San Diego
- Assignee: Advanced Liquid Logic, Inc.
- Current Assignee: Advanced Liquid Logic, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Nexsen Pruet, PLLC
- Agent E. Eric Mills
- Main IPC: C12Q1/54
- IPC: C12Q1/54 ; C12Q1/34 ; C07D311/18 ; C07D311/20 ; C07H15/203 ; C12Q1/25 ; G01N33/543 ; G01N21/64 ; C07D311/16 ; C07D405/12 ; C07D413/12 ; C07H17/075 ; C12Q1/44 ; B01L3/00
Abstract:
The invention is directed to droplet actuator devices and assay methods. The invention includes assay methods of conducting an assay comprising combining a sample with an umbelliferyl derivative, wherein the sample potentially comprises an enzyme capable of cleaving the umbelliferyl derivative and where the umbelliferyl derivative comprises an umbelliferyl core modified with one or more modifying moieties.
Public/Granted literature
- US20150184219A1 Enzyme Assays on a Droplet Actuator Public/Granted day:2015-07-02
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