Invention Grant
- Patent Title: Substituted sulfonamide compounds
- Patent Title (中): 取代磺酰胺化合物
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Application No.: US14671643Application Date: 2015-03-27
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Publication No.: US09580411B2Publication Date: 2017-02-28
- Inventor: Christine E. Brotherton-Pleiss , Huifen Chen , Shaoqing Chen , Zhi Chen , Shawn David Erickson , Anthony Estrada , Kyungjin Kim , Hongju Li , Allen John Lovey , Joseph P. Lyssikatos , Yimin Qian , Sung-Sau So , Peter Michael Wovkulich , Lin Yi
- Applicant: Hoffmann-La Roche Inc. , GENENTECH, INC.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Robert C. Hall
- Main IPC: C07D305/08
- IPC: C07D305/08 ; C07D409/12 ; C07D231/18 ; C07D401/04 ; C07D401/12 ; C07D403/04 ; C07D237/08 ; C07D239/42 ; C07D409/14 ; C07D241/12 ; C07D213/26 ; C07D213/40 ; C07C311/19 ; C07C311/16 ; C07C311/17 ; C07C311/20 ; C07D239/26 ; C07D305/06 ; C07D403/12
Abstract:
The invention is concerned with the compounds of formula (I): and salts thereof, wherein X, Y, Z, R1, R2, R3, R3′, R4, R5 and R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of Formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
Public/Granted literature
- US20150197509A1 SUBSTITUTED SULFONAMIDE SOLUTIONS Public/Granted day:2015-07-16
Information query
