Invention Grant
- Patent Title: Alkynyl alcohols and methods of use
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Application No.: US15074100Application Date: 2016-03-18
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Publication No.: US09605005B2Publication Date: 2017-03-28
- Inventor: Nicole Blaquiere , Georgette Castanedo , Jianwen A. Feng , Baihua Hu , Steven Staben , Po-wai Yuen , Guosheng Wu , Jason Burch
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Tamara A. Kale
- Priority: WOPCT/CN2013/000993 20130822; WOPCT/CN2014/078680 20140528; WOPCT/CN2014/082687 20140722
- Main IPC: C07D401/00
- IPC: C07D401/00 ; C07D513/04 ; C07D401/14 ; C07D413/14 ; C07D401/10 ; C07D403/10 ; C07D403/14 ; C07D413/10 ; C07D417/10 ; C07D471/04 ; C07D487/04 ; C07D491/048 ; C07D491/052 ; C07D495/04
Abstract:
The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.
Public/Granted literature
- US20160200739A1 ALKYNYL ALCOHOLS AND METHODS OF USE Public/Granted day:2016-07-14
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