- 专利标题： Artificial immune system: methods of use
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申请号： US14221018申请日： 2014-03-20
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公开(公告)号： US09625444B2公开(公告)日： 2017-04-18
- 发明人: William L Warren , Heather Fahlenkamp , Russell Higbee , Anatoly Kachurin , Conan Li , Mike Nguyen , Robert Parkhill , Guzman Sanchez-Schmitz , Darrell J. Irvine , Gwendalyn J. Randolph , Nir Hacohen , Bruce Torbett
- 申请人： Sanofi Pasteur VaxDesign Corporation
- 申请人地址： US FL Orlando US CA La Jolla US MA Cambridge US MA Cambridge US NY New York
- 专利权人： SANOFI PASTEUR VAXDESIGN CORPORATION,THE SCRIPPS RESEARCH INSTITUTE,MASSACHUSETTS INSTITUTE OF TECHNOLOGY,THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH,MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY
- 当前专利权人： SANOFI PASTEUR VAXDESIGN CORPORATION,THE SCRIPPS RESEARCH INSTITUTE,MASSACHUSETTS INSTITUTE OF TECHNOLOGY,THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH,MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY
- 当前专利权人地址： US FL Orlando US CA La Jolla US MA Cambridge US MA Cambridge US NY New York
- 代理机构： Wenderoth, Lind & Ponack, L.L.P.
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/02 ; A61K38/00 ; G01N33/50 ; C12N5/071
摘要：
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system.
公开/授权文献
- US20140273209A1 ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE 公开/授权日：2014-09-18
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