- Patent Title: Heterocyclic compounds having cholesterol 24-hydroxylase activity
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Application No.: US14650429Application Date: 2013-12-10
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Publication No.: US09643957B2Publication Date: 2017-05-09
- Inventor: Tatsuki Koike , Yuichi Kajita , Masato Yoshikawa , Shuhei Ikeda , Hiromi Fukuda
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2012-270445 20121211; JP2013-210439 20131007
- International Application: PCT/JP2013/083140 WO 20131210
- International Announcement: WO2014/092100 WO 20140619
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D471/08 ; C07D491/08 ; C07D213/12 ; C07D498/08 ; C07D405/12 ; C07D401/14 ; C07D417/14 ; C07D451/04 ; C07D487/10 ; C07D405/14 ; C07D413/14 ; C07D401/04 ; C07D401/12 ; C07D239/42 ; C07D413/04 ; C07D417/04 ; C07D451/02 ; C07D487/18 ; C07D491/18 ; C07D403/04 ; C07D403/14 ; C07D471/10 ; A61K9/20 ; A61K9/48 ; C07D213/72 ; C07D487/08 ; C12N9/99
Abstract:
An object of the present invention is to provide a compound having a superior CH24H inhibitory action, which is useful as an agent for the prophylaxis or treatment of epilepsy, neurodegenerative disease and the like. The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the specification, or a salt thereof.
Public/Granted literature
- US20150315209A1 HETEROCYCLIC COMPOUND Public/Granted day:2015-11-05
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