发明授权
- 专利标题： Triazolopyridines
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申请号： US13512701申请日： 2010-11-17
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公开(公告)号： US09676766B2公开(公告)日： 2017-06-13
- 发明人: Volker Schulze , Marcus Koppitz , Dirk Kosemund , Hartmut Schirok , Benjamin Bader , Philip Lienau , Antje Margret Wengner , Hans Briem , Simon Holton , Gerhard Siemeister , Stefan Prechtl , Ulf Bömer
- 申请人： Volker Schulze , Marcus Koppitz , Dirk Kosemund , Hartmut Schirok , Benjamin Bader , Philip Lienau , Antje Margret Wengner , Hans Briem , Simon Holton , Gerhard Siemeister , Stefan Prechtl , Ulf Bömer
- 申请人地址： DE Monheim
- 专利权人： BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人： BAYER INTELLECTUAL PROPERTY GMBH
- 当前专利权人地址： DE Monheim
- 代理机构： Morrison & Foerster LLP
- 优先权： EP09075535 20091130
- 国际申请： PCT/EP2010/006994 WO 20101117
- 国际公布： WO2011/063908 WO 20110603
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61K31/5377 ; C07D491/08 ; C07D471/04
摘要：
The present invention relates to triazolopyridine compounds of general formula (I) which are Monopolar Spindle 1 kinase (Mps-1 or TTK) inhibitors: Formula (I), in which R1, R2, R3, R4, and R5 are as given in the description and in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds, to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis proliferative of diseases, as well as to intermediate compounds useful in the preparation of said compounds.
公开/授权文献
- US20120328610A1 TRIAZOLOPYRIDINES 公开/授权日：2012-12-27
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