Invention Grant
- Patent Title: Antibodies specific to a novel epitope on CεMX of human membrane-bound IgE and uses thereof in treating IgE-mediated diseases
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Application No.: US14775204Application Date: 2014-03-12
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Publication No.: US09718891B2Publication Date: 2017-08-01
- Inventor: Tse Wen Chang , Chien-Jen Lin , Chien-Sheng Lu
- Applicant: Academia Sinica
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2014/024172 WO 20140312
- International Announcement: WO2014/165028 WO 20141009
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/42 ; C07K7/04

Abstract:
The present disclosure relates to anti-IgE antibodies that bind to novel antigenic epitopes of the CsmX domain, e.g., SVPHPRCHCGAGRA (SEQ ID NO: 4) and the uses thereof in treating IgE-mediated diseases.
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