Invention Grant
- Patent Title: Methods for preparing triazole agonists of the APJ receptor
-
Application No.: US15298434Application Date: 2016-10-20
-
Publication No.: US09751864B2Publication Date: 2017-09-05
- Inventor: Ning Chen , Xiaoqi Chen , Richard V. Connors , Jeffrey Deignan , Paul John Dransfield , Xiaohui Du , Zice Fu , Julie Anne Heath , Daniel B. Horne , Jonathan Houze , Matthew R. Kaller , David John Kopecky , Su-Jen Lai , Zhihua Ma , Lawrence R. McGee , Julio C. Medina , Jeffrey T. Mihalic , Nobuko Nishimura , Steven H. Olson , Vatee Pattaropong , Xiaodong Wang , Kevin Yang , Mikkel V. DeBenedetto , Robert P. Farrell , Simon J. Hedley , Ted C. Judd
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/14 ; C07D417/14 ; C07D471/04 ; C07D413/14 ; C07D413/04 ; A61K31/4439 ; A61K31/444 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/513 ; A61K45/06 ; C07B57/00 ; C07B59/00 ; C07D211/54 ; C07D213/71 ; C07D213/82 ; C07D239/26 ; C07D239/30 ; C07D241/12 ; C07D241/24 ; C07D249/08 ; C07D405/14 ; C07D401/12 ; A61K31/695 ; C07F7/08 ; A61K31/437 ; C07C311/13 ; C07D213/61 ; C07D239/34 ; C07D241/18 ; C07D295/16
Abstract:
Methods of preparing compounds of Formula VI, salts thereof, tautomers thereof, or salts of the tautomers include cyclizing compounds of Formula V, salts thereof, tautomers thereof, or salts of the tautomers. Compounds of Formula VI and Formula V have the following structures: where the definitions of the variables are provided herein.
Public/Granted literature
- US20170044131A1 TRIAZOLE AGONISTS OF THE APJ RECEPTOR Public/Granted day:2017-02-16
Information query
