- 专利标题： Coferons and methods of making and using them
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申请号： US13500857申请日： 2010-10-07
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公开(公告)号： US09771345B2公开(公告)日： 2017-09-26
- 发明人: Francis Barany , Maneesh Pingle , Sarah Filippa Giardina , Donald Bergstrom , Lee Daniel Arnold
- 申请人： Francis Barany , Maneesh Pingle , Sarah Filippa Giardina , Donald Bergstrom , Lee Daniel Arnold
- 申请人地址： US NY Ithaca US IN West Lafayette US NY New York
- 专利权人： Cornell University,Purdue Research Foundation,BlinkBio, Inc.
- 当前专利权人： Cornell University,Purdue Research Foundation,BlinkBio, Inc.
- 当前专利权人地址： US NY Ithaca US IN West Lafayette US NY New York
- 代理机构： LeClair, a Professional Corporation
- 国际申请： PCT/US2010/002708 WO 20101007
- 国际公布： WO2011/043817 WO 20110414
- 主分类号： A61K31/69
- IPC分类号： A61K31/69 ; C07D319/14 ; C07D207/12 ; C07D207/24 ; C07D209/52 ; C07D239/42 ; C07D239/54 ; C07D241/36 ; C07D263/20 ; C07D295/18 ; C07D307/80 ; C07D317/10 ; C07D317/44 ; C07D319/12 ; C07D403/06 ; C07D403/14 ; C07D405/14 ; C07D413/06 ; C07D471/14 ; C07D491/04 ; C07D491/10 ; C07D491/14 ; C07F5/02 ; C40B30/04
摘要：
The present invention is directed to a monomer useful in preparing therapeutic compounds. The monomer includes one or more pharmacophores which potentially binds to a target molecule with a dissociation constant of less than 300 μM and a linker element connected to the pharmacophore. The linker element has a molecular weight less than 500 daltons, is connected, directly or indirectly through a connector, to the pharmacophore.
公开/授权文献
- US20120295874A1 COFERONS AND METHODS OF MAKING AND USING THEM 公开/授权日：2012-11-22
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