Invention Grant
- Patent Title: Compositions and methods of modulating 15-PGDH activity
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Application No.: US14395021Application Date: 2013-04-16
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Publication No.: US09790233B2Publication Date: 2017-10-17
- Inventor: Sanford Markowitz , James K. V. Willson , Bruce A. Posner , Joseph Ready , Yongyou Zhang , Hsin-Hsiung Tai , Monika Antczak , Stanton Gerson , KiBeom Bae , Sung Yeun Yang , Amar Desai
- Applicant: CASE WESTERN RESERVE UNIVERSITY , BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM , University of Kentucky Research Foundation
- Applicant Address: US OH Cleveland US TX Austin US KY Lexington
- Assignee: Case Western Reserve University,Board of Regents of the University of Texas System,University of Kentucky Research Foundation
- Current Assignee: Case Western Reserve University,Board of Regents of the University of Texas System,University of Kentucky Research Foundation
- Current Assignee Address: US OH Cleveland US TX Austin US KY Lexington
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- International Application: PCT/US2013/036790 WO 20130416
- International Announcement: WO2013/158649 WO 20131024
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07D213/71 ; C07D213/73 ; C07D213/75 ; C07D213/76 ; C07D215/08 ; C07D237/20 ; C07D405/12 ; C07D239/42 ; C07D241/20 ; C07D261/14 ; C07D207/263 ; C07D275/03 ; C07D209/08 ; C07D277/46 ; C07D295/185 ; C07C311/21
Abstract:
Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors and 15-PGDH activators described herein.
Public/Granted literature
- US20150072998A1 COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY Public/Granted day:2015-03-12
Information query
