- Patent Title: Microbial succinic acid producers and purification of succinic acid
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Application No.: US14676317Application Date: 2015-04-01
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Publication No.: US09932612B2Publication Date: 2018-04-03
- Inventor: Hartwig Schröder , Stefan Haefner , Gregory Von Abendroth , Rajan Hollmann , Aline Raddatz , Hansgeorg Ernst , Hans Gurski
- Applicant: BASF SE
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Marshall, Gerstein & Borun LLP
- Priority: EP09152959 20090216; EP09171250 20090924
- Main IPC: C12P7/46
- IPC: C12P7/46 ; C12N1/32 ; C12N9/10 ; C12R1/01

Abstract:
The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.
Public/Granted literature
- US20150197776A1 Novel Microbial Succinic Acid Producers and Purification of Succinic Acid Public/Granted day:2015-07-16
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