Novel Microbial Succinic Acid Producers and Purification of Succinic Acid
    1.
    发明申请
    Novel Microbial Succinic Acid Producers and Purification of Succinic Acid 审中-公开
    新型微生物琥珀酸生产商和琥珀酸的纯化

    公开(公告)号:US20140127764A1

    公开(公告)日:2014-05-08

    申请号:US14150206

    申请日:2014-01-08

    Applicant: BASF SE

    CPC classification number: C12P7/46 C12N1/32 C12N9/1029 C12R1/01 C12Y203/01054

    Abstract: The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.

    Abstract translation: 本发明涉及能够利用甘油作为发酵生产琥珀酸的碳源的细菌菌株,其中所述菌株被遗传修饰,使得它们包含其内源性丙酮酸 - 甲酸裂解酶活性的失调,以及 涉及通过利用这种微生物生产有机酸,特别是琥珀酸的方法。 本发明还涉及通过阳离子交换层析对所生产的有机酸的下游加工。

    Novel Microbial Succinic Acid Producers and Purification of Succinic Acid
    2.
    发明申请
    Novel Microbial Succinic Acid Producers and Purification of Succinic Acid 审中-公开
    新型微生物琥珀酸生产商和琥珀酸的纯化

    公开(公告)号:US20150197776A1

    公开(公告)日:2015-07-16

    申请号:US14676317

    申请日:2015-04-01

    Applicant: BASF SE

    CPC classification number: C12P7/46 C12N1/32 C12N9/1029 C12R1/01 C12Y203/01054

    Abstract: The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.

    Abstract translation: 本发明涉及能够利用甘油作为发酵生产琥珀酸的碳源的细菌菌株,其中所述菌株被遗传修饰,使得它们包含其内源性丙酮酸 - 甲酸裂解酶活性的失调,以及 涉及通过利用这种微生物生产有机酸,特别是琥珀酸的方法。 本发明还涉及通过阳离子交换层析对所生产的有机酸的下游加工。

    Microbial succinic acid producers and purification of succinic acid
    3.
    发明授权
    Microbial succinic acid producers and purification of succinic acid 有权
    微生物琥珀酸生产商和琥珀酸的纯化

    公开(公告)号:US09023632B2

    公开(公告)日:2015-05-05

    申请号:US14150206

    申请日:2014-01-08

    Applicant: BASF SE

    CPC classification number: C12P7/46 C12N1/32 C12N9/1029 C12R1/01 C12Y203/01054

    Abstract: The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.

    Abstract translation: 本发明涉及能够利用甘油作为发酵生产琥珀酸的碳源的细菌菌株,其中所述菌株被遗传修饰,使得它们包含其内源性丙酮酸 - 甲酸裂解酶活性的失调,以及 涉及通过利用这种微生物生产有机酸,特别是琥珀酸的方法。 本发明还涉及通过阳离子交换层析对所生产的有机酸的下游加工。

    Reactive thermoplastic polyurethane based on blocked isocyanates

    公开(公告)号:US11214649B2

    公开(公告)日:2022-01-04

    申请号:US16482951

    申请日:2018-02-16

    Applicant: BASF SE

    Abstract: A method for producing a shaped body, containing: producing the shaped body from a composition by a powder-based layer construction process, wherein the composition contains a thermoplastic polyurethane, obtained by reacting a polyisocyanate composition and a polyol composition, the thermoplastic polyurethane is solid at least in a temperature region below 50° C. and has end groups selected from the group consisting of first end groups and second end groups, wherein the first end groups are optionally eliminated at a first temperature, and the second end groups are optionally eliminated at a second temperature, to form reactive groups on the thermoplastic polyurethane that optionally enter into a reaction with functional groups of the thermoplastic polyurethane or functional groups of a further component of the composition, and wherein the first temperature and the second temperature are each greater than or equal to 60° C.

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