Invention Grant
- Patent Title: Biological markers and methods for predicting response to B-cell antagonists
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Application No.: US15019615Application Date: 2016-02-09
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Publication No.: US09982302B2Publication Date: 2018-05-29
- Inventor: Timothy W. Behrens , Kasia Owczarczyk , Michael J. Townsend
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Morrison & Foerster LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07K14/705 ; A61K38/00
Abstract:
Biological markers that predict patient responsiveness to B-cell antagonists are provided. Also provided are methods of using such biological markers. In addition, methods for identifying patients suffering from an autoimmune disease, e.g., rheumatoid arthritis, who are not likely to respond to B-cell antagonists are provided, as are methods of treating such patients. Methods for selecting therapeutic agents to treat such patients are also provided.
Public/Granted literature
- US20160265056A1 BIOLOGICAL MARKERS AND METHODS FOR PREDICTING RESPONSE TO B-CELL ANTAGONISTS Public/Granted day:2016-09-15
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