再颁专利
- 专利标题: Treatments employing drug-containing matrices for introduction into cellular lesion areas
- 专利标题(中): 使用含药基质进行细胞损伤区域的治疗
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申请号: US255863申请日: 1988-10-11
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公开(公告)号: USRE33375E公开(公告)日: 1990-10-09
- 发明人: Edward E. Luck , Dennis M. Brown
- 申请人: Edward E. Luck , Dennis M. Brown
- 申请人地址: CA Menlo Park
- 专利权人: Matrix Pharmaceuticals, Inc.
- 当前专利权人: Matrix Pharmaceuticals, Inc.
- 当前专利权人地址: CA Menlo Park
- 主分类号: C07D519/04
- IPC分类号: C07D519/04 ; A61K9/26 ; A61K31/135 ; A61K31/475 ; A61K31/505 ; A61K31/70 ; A61K33/24 ; A61K38/00 ; A61K38/16 ; A61K38/17 ; A61K38/48 ; A61K45/08 ; A61K47/00 ; A61K47/42 ; A61L26/00 ; A61P35/00
摘要:
Treatment of cellular disorders involving abnormal solid cellular growths involves introduction of cytotoxic reagents dispersed in a physiologically acceptable proteinaceous matrix into the solid cellular growth or area of an existing or removed solid cellular growth. Enhanced effectiveness of the drug is observed, with reduced cytotoxic effects on cells distant from the site of introduction. Other drugs may be included to enhance therapeutic gain and reduce adverse affects to normal tissue.
公开/授权文献
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