- Patent Title: Intermediates for the preparation of analogs of Halichondrin B
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Application No.: US13924892Application Date: 2013-06-24
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Publication No.: USRE46965E1Publication Date: 2018-07-24
- Inventor: Brian Austad , Charles E. Chase , Francis G. Fang , Trevor Calkins , Bryan M. Lewis
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- International Application: PCT/US2005/019669 WO 20050603
- International Announcement: WO2005/118565 WO 20051215
- Main IPC: C07D307/12
- IPC: C07D307/12 ; C07F7/18 ; C07D407/06 ; C07D407/14 ; C07D493/04 ; C07D493/08 ; C07D493/18 ; C07D493/22 ; C07D493/20 ; C07D317/72 ; C07H15/26 ; C07C33/42 ; A61K31/341 ; C07D493/10 ; C07D307/28 ; C07D307/33

Abstract:
The present invention provides macrocyclic compounds, synthesis of the same and intermediates thereto. Such compounds, and compositions thereof, are useful for treating or preventing proliferative disorders Formula (F-4).
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