Invention Application
- Patent Title: C-GLYCOLIPIDS WITH ENHANCED TH-1 PROFILE
- Patent Title (中): 具有增强TH-1型材的C-GLYCOLIPIDS
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Application No.: PCT/US2007069461Application Date: 2007-05-22
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Publication No.: WO2007137258A2Publication Date: 2007-11-29
- Inventor: TSUJI MORIYA , CHEN GUANGWU , FRANCK RICHARD , YANG GUANGLI
- Applicant: UNIV NEW YORK STATE RES FOUND , UNIV CITY , AARON DIAMOND AIDS RES CT FOR , TSUJI MORIYA , CHEN GUANGWU , FRANCK RICHARD , YANG GUANGLI
- Assignee: UNIV NEW YORK STATE RES FOUND,UNIV CITY,AARON DIAMOND AIDS RES CT FOR,TSUJI MORIYA,CHEN GUANGWU,FRANCK RICHARD,YANG GUANGLI
- Current Assignee: UNIV NEW YORK STATE RES FOUND,UNIV CITY,AARON DIAMOND AIDS RES CT FOR,TSUJI MORIYA,CHEN GUANGWU,FRANCK RICHARD,YANG GUANGLI
- Priority: US80273906 2006-05-22
- Main IPC: A61K31/7008
- IPC: A61K31/7008
Abstract:
The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI -type immune response characterized by enhanced IL- 12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants.
Information query
