Invention Application
- Patent Title: CLASSIFICATION OF NUCLEIC ACID TEMPLATES
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Application No.: PCT/US2009/006517Application Date: 2009-12-10
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Publication No.: WO2010068289A2Publication Date: 2010-06-17
- Inventor: FLUSBERG, Benjamin , TURNER, Stephen , LEE, Jessica , JIA, Lei , KORLACH, Jonas , SORENSON, Jon , WEBSTER, Dale , LYLE, John , TRAVERS, Kevin , HANES, Jeremiah
- Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , FLUSBERG, Benjamin , TURNER, Stephen , LEE, Jessica , JIA, Lei , KORLACH, Jonas , SORENSON, Jon , WEBSTER, Dale , LYLE, John , TRAVERS, Kevin , HANES, Jeremiah
- Applicant Address: 1505 Adams Drive Menlo Park, CA 94025 US
- Assignee: PACIFIC BIOSCIENCES OF CALIFORNIA, INC.,FLUSBERG, Benjamin,TURNER, Stephen,LEE, Jessica,JIA, Lei,KORLACH, Jonas,SORENSON, Jon,WEBSTER, Dale,LYLE, John,TRAVERS, Kevin,HANES, Jeremiah
- Current Assignee: PACIFIC BIOSCIENCES OF CALIFORNIA, INC.,FLUSBERG, Benjamin,TURNER, Stephen,LEE, Jessica,JIA, Lei,KORLACH, Jonas,SORENSON, Jon,WEBSTER, Dale,LYLE, John,TRAVERS, Kevin,HANES, Jeremiah
- Current Assignee Address: 1505 Adams Drive Menlo Park, CA 94025 US
- Agency: QUINE, Jonathan, Alan et al.
- Priority: US61/186,661 20090612; US61/180,350 20090521; US61/201,551 20081211
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N15/10
Abstract:
Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Information query
