发明申请
- 专利标题： HOST CELLS FOR DICARBOXYLIC ACID PRODUCTION
- 专利标题（中）： 用于生产二羧酸的宿主细胞
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申请号： PCT/EP2016/082415申请日： 2016-12-22
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公开(公告)号： WO2017109091A1公开(公告)日： 2017-06-29
- 发明人: LOS, Alrik Pieter , ZHAO, Zheng , VERWAAL, René , PRONK, Jacobus Thomas , POLDERMANS, Rolf
- 申请人： DSM IP ASSETS B.V.
- 申请人地址： Het Overloon 1 6411 TE Heerlen NL
- 专利权人： DSM IP ASSETS B.V.
- 当前专利权人： DSM IP ASSETS B.V.
- 当前专利权人地址： Het Overloon 1 6411 TE Heerlen NL
- 代理机构： DELAMARRE, Soazig Claude Marie
- 优先权： EP15202593.8 20151223
- 主分类号： C12N9/04
- IPC分类号： C12N9/04 ; C12N9/02 ; C12P7/46 ; C12N1/16 ; C12R1/865
摘要：
The present invention relates to a host cell which is capable of producing a dicarboxylic acid and which comprises at least one genetic modification in its genome resulting in the deficiency of at least one enzymatic step catalysing the oxidation of a cofactor. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting such a host cell in a suitable fermentation medium and producing the dicarboxylic acid.
