METHOD TO ENHANCE TISSUE ACCUMULATION OF RADIOLABELED COMPOUNDS
    2.
    发明公开
    METHOD TO ENHANCE TISSUE ACCUMULATION OF RADIOLABELED COMPOUNDS 有权
    一种改善的放射性化合物在组织的积累

    公开(公告)号:EP0961591A1

    公开(公告)日:1999-12-08

    申请号:EP98966733.0

    申请日:1998-11-23

    IPC分类号: A61B19 A61K51

    CPC分类号: A61K51/121

    摘要: Administration of a radioisotopic compound by infusion over a period of time greater than two hours, preferably greater than twelve hours, greatly increases the maximum radioactivity that accumulates in the target cell. The efficacy of the administration of the radiolabeled compound can be increased about five times higher than prior bolus injection or short infusion methods. This method enhances the tumor to background ratio by increasing the actual radioligand accumulated inside the tumor cells. This technique works for any radiolabeled compound whose cellular uptake is limited by a cellular process of either binding to a cellular receptor or to a transport protein. Once the radiolabeled compound is bound and internalized, the ability of an unlabeled compound to compete with the radioligand is markedly decreased. The primary factor governing residence time after internalization is the physical half-life of the radioisotope, not biologic half-life.

    FOLDING SOCCER GOAL
    3.
    发明公开
    FOLDING SOCCER GOAL 失效
    折叠式足球

    公开(公告)号:EP0938354A2

    公开(公告)日:1999-09-01

    申请号:EP97913353.0

    申请日:1997-10-30

    IPC分类号: A63B63

    摘要: A folding soccer goal, consisting of a goalpost, backstay bars, and a net, wherein the goalpost has a horizontal crossbar and two vertical posts foldably attached to the crossbar; the backstay bars foldably attach to the goalpost and extend outward and downward therefrom; a hinged foot assembly is connected to the bottom of each vertical post wherein the foot is adapted for attachment to a playing surface; also disclosed is a method for erecting a soccer goal including the steps of laying the goal on the playing surface, positioning the feet against the playing surface, attaching the feet to the playing surface, raising the posts about the hinges to a substantially vertical position over the feet, and securing the posts in a substantially vertical position.

    Improvements relating to a vacuum servo unit for use in traction control
    10.
    发明公开
    Improvements relating to a vacuum servo unit for use in traction control 失效
    与真空伺服单元相关的改进,用于跟踪控制

    公开(公告)号:EP0417945A3

    公开(公告)日:1991-04-24

    申请号:EP90309561.0

    申请日:1990-08-31

    摘要: The present specification discloses a servo unit for use in a vehicle braking system, the servo unit comprising a housing (1) within which a flexible diaphragm (7) separates a vacuum pressure chamber (3) from an atmospheric pressure chamber (5). An actuator rod assembly (11) extends through the housing (1) and includes a valve assembly (17) having a valve control piston (23) which has a laterally extending key (21), the key (21) being engageable with a fixed stop in the housing (1) to limit the movement of the valve control piston (23) and cause a balance in the valve assembly (17) between the vacuum and atmospheric pressure. A solenoid valve (25) is also provided, the solenoid valve (25) being controllable to either connect a flexible passage member (29) extending around the actuator rod assembly (11) across the vacuum pressure chamber (3) between the housing (1) and the diaphragm (7) in the region of the valve assembly (17), to said vacuum pressure chamber (5), or to connect both said flexible passage member (29) and a bypass (31; 37,39; 35; 41,45; 47) leading from the solenoid valve to said atmospheric pressure chamber (5), to the atmosphere. The bypass incorporates a one-way valve (33;49).