-
公开(公告)号：EP3452455A1
公开(公告)日：2019-03-13
申请号：EP17793403.1
申请日：2017-05-05
IPC分类号： C07D235/18 , C07D235/32 , C07D471/04 , C07D487/04 , C07D263/56 , A61K31/437 , A61K31/519 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P43/00 , A61P13/12 , A61P3/10 , A61P7/00
-
2.发明公开
公开(公告)号：EP3452045A1
公开(公告)日：2019-03-13
申请号：EP17793335.5
申请日：2017-05-04
-
3.发明公开SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS 审中-公开取代的吡咯并[1,2-a]嘧啶类化合物及其在治疗医学病症中的应用
公开(公告)号：EP3215509A1
公开(公告)日：2017-09-13
申请号：EP15856385.8
申请日：2015-11-06
IPC分类号： C07D487/04 , A61K31/519 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P43/00
CPC分类号： A61K31/519 , A61K31/165 , A61P25/16 , A61P25/18 , C07D487/04 , C07D519/00
摘要： The invention provides substituted pyrrolo[1,2-a]pyrimidines and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrrolo[1,2-a]pyrimidines compounds described herein include substituted 2,4-dimethyl-N-phenylpyrrolo[1,2-a]pyrimidine-8-carboxamide compounds and variants thereof.
摘要翻译： 本发明提供取代的吡咯并[1,2-a]嘧啶和相关的有机化合物，含有这些化合物的组合物，医学试剂盒以及使用这些化合物和组合物治疗医学病症例如戈谢病，帕金森病，路易体 疾病，痴呆或多系统萎缩。 本文所述的示例性取代的吡咯并[1,2-a]嘧啶化合物包括取代的2,4-二甲基-N-苯基吡咯并[1,2-a]嘧啶-8-甲酰胺化合物及其变体。
-
4.发明公开
公开(公告)号：EP3452480A1
公开(公告)日：2019-03-13
申请号：EP17793401.5
申请日：2017-05-05
IPC分类号： C07D487/04 , C07D239/74 , C07D239/78 , C07D239/80 , C07D239/84 , C07D239/90 , A61K31/53 , A61K31/517 , A61P3/10 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P27/06 , C07D409/12 , C07D405/12 , C07D413/12 , C07D407/12
-
5.发明公开
公开(公告)号：EP3215509A4
公开(公告)日：2018-03-14
申请号：EP15856385
申请日：2015-11-06
IPC分类号： C07D487/04 , A61K31/519 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P43/00
CPC分类号： C07D487/04 , C07D519/00
摘要： The invention provides substituted pyrrolo[l,2-a]pyrimi dines and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrrolo[1,2-a]pyrimidines compounds described herein include substituted 2,4-dimethyl-N-phenylpyrrolo[l,2-a]pyrimidine-8-carboxamide compounds and variants thereof.
-
6.发明公开SUBSTITUTED PYRAZOLO(1,5-A)PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS 审中-公开取代的吡唑并（1,5-A）嘧啶及其在治疗医疗失调中的应用
公开(公告)号：EP3215511A1
公开(公告)日：2017-09-13
申请号：EP15857508.4
申请日：2015-11-06
IPC分类号： C07D487/04 , A61K31/519 , A61P25/16 , A61P27/06 , A61P3/10 , A61P13/12 , A61P25/24 , A61P25/28 , A61P25/08 , A61P25/18 , A61P25/22 , A61P43/00
CPC分类号： C07D487/04 , A61K31/519
摘要： The invention provides substituted pyrazolo[1,5-a]pyrimidine and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrazolo[1,5-a]pyrimidine compounds described herein include 5,7-dimethyl-N-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide compounds and variants thereof.
摘要翻译： 本发明提供取代的吡唑并[1,5-a]嘧啶和相关的有机化合物，含有这些化合物的组合物，医学试剂盒以及使用这些化合物和组合物治疗医学病症例如戈谢病，帕金森病，路易体病，痴呆或 多系统萎缩，病人。 本文所述的示例性取代的吡唑并[1,5-a]嘧啶化合物包括5,7-二甲基-N-苯基吡唑并[1,5-a]嘧啶-3-甲酰胺化合物及其变体。
-
7.发明公开SUBSTITUTED IMIDAZO[1,5-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS 审中-公开取代的咪唑并[1,5-a]嘧啶及其在治疗医学病症中的用途
公开(公告)号：EP3215510A1
公开(公告)日：2017-09-13
申请号：EP15856978.0
申请日：2015-11-06
IPC分类号： C07D487/04 , A61K31/519 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P43/00
CPC分类号： A61K31/519 , A61K31/13 , A61K31/16 , A61K2300/00 , C07D487/04 , C07D519/00
摘要： The invention provides substituted imidazo┌1,5-a┐pyrimidines and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,5-a]pyrimidine compounds described herein include substituted 2,4-dimethyl-N-phenylimidazo[1,5-a]pyrimidine-8-carbox-amide compounds and variants thereof.
摘要翻译： 本发明提供取代的咪唑并[1,5-a]嘧啶和相关的有机化合物，含有这些化合物的组合物，医学试剂盒，以及使用这些化合物和组合物治疗医学病症的方法，例如戈谢病，帕金森病，路易体病 ，痴呆或多系统萎缩。 本文所述的示例性取代的咪唑并[1,5-a]嘧啶化合物包括取代的2,4-二甲基-N-苯基咪唑并[1,5-a]嘧啶-8-甲酰胺化合物及其变体。
-
8.发明公开
公开(公告)号：EP3440080A1
公开(公告)日：2019-02-13
申请号：EP17779797.4
申请日：2017-04-06
-
公开(公告)号：EP3313386A1
公开(公告)日：2018-05-02
申请号：EP16815289.0
申请日：2016-06-23
IPC分类号： A61K31/17 , A61K31/423 , A61K31/513 , A61P43/00
CPC分类号： A61K31/513 , A61K31/423
摘要： The invention relates to a method of treating lysosomal storage disorders caused by a deficiency in lysosomal hydrolase activity. The method comprises administering an effective amount of an acid ceramidase inhibitor to the subject thereby to treat the lysosomal storage disorder.
-
10.发明公开
公开(公告)号：EP3215511A4
公开(公告)日：2018-02-28
申请号：EP15857508
申请日：2015-11-06
IPC分类号： C07D487/04 , A61K31/519 , A61P3/10 , A61P13/12 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/06 , A61P43/00
CPC分类号： C07D487/04 , A61K31/519
摘要： The invention provides substituted pyrazolol1,5-alpyrimidine and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrazolo111,5-alpyrimidine compounds described herein include 5,7-dimethyl-N-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide compounds and variants thereof.
-
-
-
-
-
-
-
-
-
搜索结果
19 条记录 (耗时 0.013 秒)
