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公开(公告)号:EP4436968A1
公开(公告)日:2024-10-02
申请号:EP22843901.4
申请日:2022-11-07
Applicant: Ventus Therapeutics U.S., Inc.
Inventor: BEVERIDGE, Ramsay , BURCH, Jason , FADER, Lee , BOILY, Marc-Olivier , ST-ONGE, Miguel , DORICH, Stéphane , CHAGNON, Felix , DURET, Guillaume
IPC: C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , A61P3/00 , A61P9/00 , A61P11/00 , A61P13/12 , A61P17/00 , A61P25/00 , A61P25/16 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/00 , A61P37/00
CPC classification number: C07D417/12 , C07D417/14 , C07D498/04 , C07D513/04 , C07D487/04 , C07D471/04 , A61P35/00 , A61P29/00 , A61P37/00 , A61P31/00 , A61P25/00 , A61P3/00 , A61P9/00 , A61P11/00 , A61P13/12 , A61P27/02 , A61P17/00 , A61P25/16 , A61P25/28
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公开(公告)号:EP4417261A3
公开(公告)日:2024-10-02
申请号:EP24168584.1
申请日:2017-04-19
Applicant: Genome Research Limited
Inventor: NEVILLE, Anne , BROWNE, Hilary , FORSTER, Sam , LAWLEY, Trevor
IPC: A61K35/742 , A61P31/04
CPC classification number: A61K35/742 , A61P1/00 , A61P1/04 , A61P1/16 , A61P11/06 , A61P19/02 , A61P25/00 , A61P25/16 , A61P25/28 , A61P3/00 , A61P3/04 , A61P31/04 , A61P35/00 , A61P3/06 , A61P37/02 , A61P37/08 , A61P43/00 , A61P7/00 , A61P9/00 , A61P3/10 , Y02A50/30
Abstract: The invention relates to therapeutic compositions comprising at least one isolated bacterium and a pharmaceutically acceptable excipient, as well as methods of preparing such therapeutic compositions. The therapeutic compositions find application in the treatment of dysbiosis, in particular dysbiosis of the gastrointestinal tract.
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公开(公告)号:EP3506900B1
公开(公告)日:2024-10-02
申请号:EP17761725.5
申请日:2017-08-24
IPC: A61K31/4465 , A61K45/06 , A61P9/02 , A61K31/165 , A61K31/192 , A61K31/44 , A61K31/573 , A61P1/08
CPC classification number: A61K45/06 , A61K31/165 , A61K31/573 , A61K31/198 , A61K31/4425 , A61K31/4465 , C07D211/22 , A61P1/08 , A61P25/00 , A61P25/16 , A61P43/00 , A61P9/02
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公开(公告)号:EP4433459A1
公开(公告)日:2024-09-25
申请号:EP22818338.0
申请日:2022-11-17
Applicant: F. Hoffmann-La Roche AG
Inventor: AITKEN, Lewis Scott , ALANINE, Thomas Alexander , BOUCHE, Lea Aurelie , GUBA, Wolfgang , JAESCHKE, Georg , MESCH, Stefanie Katharina , THOM, Stephen Malcom , TOSSTORFF, Andreas Michael , SCHNIDER, Christian , STEINER, Sandra , HERR, Sabrina
IPC: C07D237/24 , C07D401/12 , C07D471/04 , A61K9/20 , A61K9/48 , A61P11/00 , A61P11/06 , A61P25/16 , A61P25/28 , A61K31/501
CPC classification number: C07D237/24 , C07D401/12 , C07D471/04 , A61P11/00 , A61P11/06 , A61P25/16 , A61P25/28 , A61K9/2054 , A61K9/2059 , A61K9/4866
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公开(公告)号:EP4379053A3
公开(公告)日:2024-09-18
申请号:EP24156927.6
申请日:2019-10-09
Applicant: The University of British Columbia
Inventor: KULKARNI, Jayesh , HILL, Austin , CULLIS, Pieter , LEAVITT, Blair , PETKAU, Terri , WAGNER, Pamela
IPC: C12N15/88 , C12N9/22 , C12N15/113 , A61K9/50 , A61K47/12 , A61K47/14 , A61P25/16 , A61P25/28 , A61K9/00 , A61K9/127 , C12N15/11
CPC classification number: A61P25/28 , A61P25/16 , C12N15/113 , C12N15/88 , C12N2310/2020170501 , C12N15/111 , C12N2310/1420130101 , A61K9/1272 , A61K9/0019
Abstract: Lipid-based vesicles, typically herein called transfection competent vesicles (TCVs), configured to safely and efficiently deliver DNA, RNA, other nucleic acid and protein cargoes into target cells. The safety and efficiency are each, and both, achieved in part by eliminating organic solvents such as ethanol and detergents such as sodium dodecyl sulfate from the TCV loading processes (i.e., inserting a cargo into the TCV), TCV storage processes, and/or TCV delivery processes. The cargoes can also comprise nucleic acids complexed with a protein, such as a ribonucleoprotein (RNP). The systems, compositions, devices and methods, etc., herein, in some embodiments, can provide empty TCVs that can if desired be loaded at the bench without use of specialized equipment.
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公开(公告)号:EP4427738A2
公开(公告)日:2024-09-11
申请号:EP24191543.8
申请日:2020-07-31
Applicant: Enterin, Inc.
Inventor: BARBUT, Denise , ZASLOFF, Michael
IPC: A61K9/00
CPC classification number: A61K31/575 , A61P17/02 , A61K9/0014 , A61P25/16 , A61P1/10 , A61K9/006 , A61K47/10 , A61K9/08 , Y02A50/30
Abstract: The present application relates generally to a method of treating a cutaneous or mucosal wound in a subject in need comprising topically administering to the wound site a therapeutically effective amount of a topical pharmaceutical composition comprising at least one aminosterol or a salt or derivative thereof. Also provided are methods for treating, preventing, and/or slowing the onset or progression of a disease or condition, or a symptom thereof, amenable to treatment with an aminosterol or a salt or derivative thereof in a subject in need, comprising administering to the subject a therapeutically effective amount of at least one aminosterol or a salt or derivative thereof, wherein the subject is not lying down.
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公开(公告)号:EP4427039A1
公开(公告)日:2024-09-11
申请号:EP22888562.0
申请日:2022-10-31
Applicant: Nitrase Therapeutics, Inc.
Inventor: HUSSAIN, Sami , GRISWOLD-PRENNER, Irene
CPC classification number: C07K16/18 , A61P25/16 , G01N33/6896 , G01N2333/470320130101
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公开(公告)号:EP4419117A1
公开(公告)日:2024-08-28
申请号:EP22814231.1
申请日:2022-10-24
Applicant: Sana Biotechnology, Inc.
Inventor: FRY, Terry J. , JOHNSON, Adam James , DOWDLE, William
IPC: A61K35/17 , C12N5/0783 , C12N15/90 , A61P3/10 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/28 , A61P35/00 , A61P37/06
CPC classification number: C12N5/0636 , A61P35/00 , A61P37/06 , A61P3/10 , A61P25/16 , A61P25/28 , A61P25/08 , A61P25/00 , C07K14/7051 , C07K14/70596 , C12N15/1138 , C12N2310/2020170501 , C12N2510/0020130101 , A61K39/4611 , A61K39/464411
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公开(公告)号:EP4416179A1
公开(公告)日:2024-08-21
申请号:EP22801673.9
申请日:2022-10-14
Inventor: WEINER, Howard L. , CHITNIS, Tanuja , SINGHAL, Tarun , SHAILUBHAI, Kunwar
CPC classification number: C07K16/2809 , C07K2317/2120130101 , C07K2317/7120130101 , A61K2039/50520130101 , A61K2039/54320130101 , A61K2039/54520130101 , A61P25/28 , A61P25/08 , A61P25/16 , A61P9/10
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公开(公告)号:EP3782628B1
公开(公告)日:2024-08-07
申请号:EP20186939.3
申请日:2014-03-14
IPC: A61K31/7088 , A61K48/00 , C12N15/11 , C12N15/09
CPC classification number: C12N2760/1884120130101 , A61K48/005 , A61K31/7088 , A61K38/1709 , C07K14/47 , C12N15/113 , C12N2310/1420130101 , C12N2310/53120130101 , A61P1/00 , A61P1/02 , A61P1/04 , A61P1/16 , A61P1/18 , A61P11/00 , A61P13/00 , A61P13/02 , A61P13/08 , A61P13/10 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/14 , A61P19/00 , A61P19/02 , A61P21/00 , A61P21/02 , A61P21/04 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/28 , A61P25/32 , A61P27/02 , A61P27/16 , A61P29/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , A61P37/08 , A61P43/00 , A61P5/00 , A61P5/38 , A61P7/00 , A61P7/02 , A61P7/06 , A61P9/00 , A61P9/10 , A61P3/10
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