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1.发明公开DIPHENYLAZETIDINONE DERIVATIVES FOR TREATING DISORDERS OF THE LIPID METABOLISM 审中-公开Diphenylazetidinone衍生物为血脂异常代谢的治疗
公开(公告)号：EP1521742A1
公开(公告)日：2005-04-13
申请号：EP03762763.5
申请日：2003-07-01
申请人： AstraZeneca AB
发明人： STARKE, Ingemar , DAHLSTROM, Mikael, Ulf, Johan , LINDQVIST, Ann-Margret , NORDBERG, Mats, Peter , SKJARET, Tore , LEMURELL, Malin, Anita
IPC分类号： C07D205/08 , C07D409/12 , A61K31/397 , A61P3/06 , A61P9/10
CPC分类号： C07D409/12 , C07D205/08
摘要： Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
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公开(公告)号：EP1597245A1
公开(公告)日：2005-11-23
申请号：EP04713573.6
申请日：2004-02-23
申请人： AstraZeneca AB
发明人： STARKE, Ingemar , ALENFALK, Suzanne , NORDBERG, Mats, Peter , DAHLSTROM, Mikael, Ulf, Johan , BOSTROM, Stig, Jonas , LEMURELL, Malin, Anita , WALLBERG, Andreas, Christer
IPC分类号： C07D281/10 , C07D337/08 , A61K31/38 , A61K31/554 , A61P3/06
CPC分类号： C07D281/10 , C07D337/08
摘要： Compounds of formula: (I) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
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公开(公告)号：EP3292105B1
公开(公告)日：2019-10-02
申请号：EP16720116.9
申请日：2016-05-03
申请人： AstraZeneca AB
发明人： BRODDEFALK, Johan, Olof , EMTENÄS, Hans, Fredrik , GRANBERG, Kenneth, Lars , LEMURELL, Malin, Anita , PETTERSEN, Daniel, Tor , PLOWRIGHT, Alleyn, Thomas , ULANDER, Lars, Johan, Andreas
IPC分类号： C07D231/40 , C07D231/44 , C07D231/50 , C07D413/12 , C07D417/12 , C07D487/04 , C07D498/04 , A61K31/4155 , A61P9/00
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公开(公告)号：EP3670499A1
公开(公告)日：2020-06-24
申请号：EP19199606.5
申请日：2016-05-03
申请人： Astrazeneca AB
发明人： BRODDEFALK, Johan Olof , EMTENÄS, Hans Fredrik , GRANBERG, Kenneth, Lars , LEMURELL, Malin, Anita , PETTERSEN, Daniel, Tor , PLOWRIGHT, Alleyn, Thomas , ULANDER, Lars Johan, Andreas
IPC分类号： C07D231/40 , C07D231/44 , C07D231/50 , C07D413/12 , C07D417/12 , C07D487/04 , C07D498/04 , A61K31/4155 , A61P9/00
摘要： The present application relates to novel compounds of formula (I)
to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.-
5.发明公开PYRAZOLE DERIVATIVES USEFUL AS 5-LIPOXYGENASE ACTIVATING PROTEIN (FLAP) INHIBITORS 审中-公开可用作5-脂氧合酶活化蛋白（FLAP）抑制剂的吡唑衍生物
公开(公告)号：EP3292105A1
公开(公告)日：2018-03-14
申请号：EP16720116.9
申请日：2016-05-03
申请人： AstraZeneca AB
发明人： BRODDEFALK, Johan, Olof , EMTENÄS, Hans, Fredrik , GRANBERG, Kenneth, Lars , LEMURELL, Malin, Anita , PETTERSEN, Daniel, Tor , PLOWRIGHT, Alleyn, Thomas , ULANDER, Lars, Johan, Andreas
IPC分类号： C07D231/40 , C07D231/44 , C07D231/50 , C07D413/12 , C07D417/12 , C07D487/04 , C07D498/04 , A61K31/4155 , A61P9/00
CPC分类号： C07D487/04 , C07D231/40 , C07D231/44 , C07D231/50 , C07D413/12 , C07D417/12 , C07D498/04
摘要： to their utility in treating and/or preventing clinical conditions including cardiovascular diseases (CVD), to methods for their therapeutic use, to pharmaceutical compositions containing them and to processes for preparing such compounds.
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