-
1.发明公开Molecular constructs and methods of use for detection of biochemical reactions 有权Methode zur Anwendung Molekulare Konstrukte zur Detektion biochemischer Reaktionen
公开(公告)号：EP1394270A2
公开(公告)日：2004-03-03
申请号：EP03018640.7
申请日：2003-08-20
发明人： Yang, Jiacheng
IPC分类号： C12Q1/68 , G01N33/543 , C12Q1/25
CPC分类号： C12Q1/6837 , C07K14/003 , C07K2319/50 , C12N2310/3181 , C12Q1/37 , C12Q1/42 , C12Q1/48 , C12Q1/485 , C12Q1/6827 , G01N33/54366 , G01N33/6893 , G01N33/6896 , C12Q2525/107 , C12Q2525/161 , C12Q2537/137 , C12Q2565/518 , C12Q2563/119
摘要： The present invention relates to molecular constructs and methods of their use in detecting biochemical reactions. In particular, the invention relates to a molecular construct having a capture portion and a substrate portion, where the capture portion isolates the construct from a sample medium, and the substrate portion enables the construct to be acted upon and undergo a physical change which can be detected and measured. These molecular constructs may be used in diagnostic assays, genetic screening for potential risks of certain diseases in individuals, and drug discovery and toxicogenomics, using high throughput screening of compounds.
摘要翻译： 本发明涉及其用于检测生物化学反应的分子构建体及其方法。 特别地，本发明涉及具有捕获部分和底物部分的分子构建体，其中捕获部分将构建体与样品介质隔离，并且衬底部分使构建体能够作用于并经历物理变化，其可以是 检测和测量。 这些分子构建体可用于诊断测定，遗传筛选个体中某些疾病的潜在风险，以及药物发现和毒物基因组学，使用化合物的高通量筛选。
-
2.发明公开Arrays of microparticles and methods of preparation thereof 审中-公开Mikropartikelanordnungen und Herstellungsverfahrendafür
公开(公告)号：EP2319617A1
公开(公告)日：2011-05-11
申请号：EP10180700.6
申请日：2002-12-27
发明人： Seul, Michael , Chau, Chiu , Huang, Hui , Banerjee, Sukanta , Hong, Ye , Yang, Jiacheng
IPC分类号： B01J19/00
CPC分类号： C12Q1/6837 , B01J19/0046 , B01J2219/00274 , B01J2219/00317 , B01J2219/00466 , B01J2219/00468 , B01J2219/005 , B01J2219/00545 , B01J2219/00648 , B01J2219/00662 , G01N33/54306 , C12Q2563/149
摘要： The present invention provides methods for quality control of biochip manufacture, preferably where the substrate is a semiconductor and the biochip carries bio-functionalized microbeads.
摘要翻译： 本发明提供了用于生物芯片制造的质量控制的方法，优选地，其中基底是半导体，并且生物芯片承载生物官能化的微珠。
-
3.发明公开Molecular constructs and methods of use for detection of biochemical reactions 有权分子结构和其用于检测生化反应的使用方法
公开(公告)号：EP1394270A3
公开(公告)日：2004-05-06
申请号：EP03018640.7
申请日：2003-08-20
发明人： Yang, Jiacheng
IPC分类号： C12Q1/68 , G01N33/543 , C12Q1/25
CPC分类号： C12Q1/6837 , C07K14/003 , C07K2319/50 , C12N2310/3181 , C12Q1/37 , C12Q1/42 , C12Q1/48 , C12Q1/485 , C12Q1/6827 , G01N33/54366 , G01N33/6893 , G01N33/6896 , C12Q2525/107 , C12Q2525/161 , C12Q2537/137 , C12Q2565/518 , C12Q2563/119
摘要： The present invention relates to molecular constructs and methods of their use in detecting biochemical reactions. In particular, the invention relates to a molecular construct having a capture portion and a substrate portion, where the capture portion isolates the construct from a sample medium, and the substrate portion enables the construct to be acted upon and undergo a physical change which can be detected and measured. These molecular constructs may be used in diagnostic assays, genetic screening for potential risks of certain diseases in individuals, and drug discovery and toxicogenomics, using high throughput screening of compounds.
-
公开(公告)号：EP2565648B1
公开(公告)日：2017-07-19
申请号：EP12180829.9
申请日：2002-12-27
发明人： Seul, Michael , Chau, Chiu Wo , Huang, Hui , Banerjee, Sukanta , Hong, Ye , Yang, Jiacheng
IPC分类号： G01N33/543 , G01N33/533 , C07H1/00 , C07H21/00 , C12Q1/68
CPC分类号： C12Q1/6837 , B01J19/0046 , B01J2219/00274 , B01J2219/00317 , B01J2219/00466 , B01J2219/00468 , B01J2219/005 , B01J2219/00545 , B01J2219/00648 , B01J2219/00662 , G01N33/54306 , C12Q2563/149
摘要： The present invention provides methods for quality control of biochip manufacture, preferably where the substrate is a semiconductor and the biochip carries bio-functionalized microbeads.
摘要翻译： 本发明提供了用于生物芯片制造的质量控制的方法，优选地，其中衬底是半导体并且生物芯片承载生物功能化的微珠。
-
5.发明公开Arrays of microparticles and methods of preparation thereof 有权Mikropartikelanordnungen und Herstellungsverfahrendafür
公开(公告)号：EP2565648A1
公开(公告)日：2013-03-06
申请号：EP12180829.9
申请日：2002-12-27
发明人： Seul, Michael , Chau, Chiu Wo , Huang, Hui , Banerjee, Sukanta , Hong, Ye , Yang, Jiacheng
IPC分类号： G01N33/543 , G01N33/533 , C07H1/00 , C07H21/00 , C12Q1/68
CPC分类号： C12Q1/6837 , B01J19/0046 , B01J2219/00274 , B01J2219/00317 , B01J2219/00466 , B01J2219/00468 , B01J2219/005 , B01J2219/00545 , B01J2219/00648 , B01J2219/00662 , G01N33/54306 , C12Q2563/149
摘要： This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chip and/or multichip arrays of this invention are useful for chemical and biological arrays.
摘要翻译： 本发明提供了高单位密度的微粒阵列和组装这种阵列的方法。 阵列中的微粒可以用给定目标分析物特异性的化学或生物实体来官能化。 根据本文所述的方法，本发明的高单位密度阵列形成在可以组合以形成多芯片阵列的芯片上。 本发明的芯片和/或多芯片阵列可用于化学和生物阵列。
-
6.发明授权
公开(公告)号：EP1394270B1
公开(公告)日：2008-03-12
申请号：EP03018640.7
申请日：2003-08-20
发明人： Yang, Jiacheng
IPC分类号： C12Q1/68 , G01N33/543 , C12Q1/25
CPC分类号： C12Q1/6837 , C07K14/003 , C07K2319/50 , C12N2310/3181 , C12Q1/37 , C12Q1/42 , C12Q1/48 , C12Q1/485 , C12Q1/6827 , G01N33/54366 , G01N33/6893 , G01N33/6896 , C12Q2525/107 , C12Q2525/161 , C12Q2537/137 , C12Q2565/518 , C12Q2563/119
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.022 秒)
