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公开(公告)号:EP3638229A1
公开(公告)日:2020-04-22
申请号:EP18816547.6
申请日:2018-06-14
发明人: KOTIAN, Pravin L. , BABU, Yarlagadda,S. , KUMAR, V. Satish , ZHANG, Weihe , LU, Peng-Cheng , RAMAN, Krishnan
IPC分类号: A61K31/417 , A61K31/4184 , A61K31/517 , C07D233/54 , C07D239/12 , C07D239/14
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2.
公开(公告)号:EP3939658A1
公开(公告)日:2022-01-19
申请号:EP21183553.3
申请日:2019-04-05
发明人: KOTIAN, Pravin L. , BABU, Yarlagadda S. , ZHANG, Weihe , LU, Peng-Cheng , WU, Minwan , LV, Wei , NGUYEN, Trung Xuan , DANG, Zhao , CHINTAREDDY, Venkat R. , KUMAR, V. Satish , RAMAN, Krishnan
IPC分类号: A61P9/00 , A61P13/12 , A61P25/28 , A61P37/00 , C07D209/08 , C07D231/56 , C07D235/08 , C07D239/70 , C07D261/20 , C07D307/79 , C07D333/54 , C07D403/10 , C07D405/12 , C07D407/04 , C07D407/10 , C07D409/12 , C07D471/04 , C07D487/04 , C07D307/81
摘要: Disclosed are compounds of formulae I and II, and pharmaceutically acceptable salts and prodrugs thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.
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公开(公告)号:EP4323344A1
公开(公告)日:2024-02-21
申请号:EP22788930.0
申请日:2022-04-14
发明人: KOTIAN, Pravin L. , BABU, Yarlagadda S. , ZHANG, Weihe , LU, Peng-Cheng , DANG, Zhao , RAMAN, Krishnan
IPC分类号: C07D231/14 , C07D401/04 , C07D401/12
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公开(公告)号:EP4041717A1
公开(公告)日:2022-08-17
申请号:EP20875434.1
申请日:2020-10-09
发明人: KOTIAN, Pravin L. , BABU, Yarlagadda S. , ZHANG, Weihe , LU, Peng-Cheng , SPAULDING, Andrew E. , WU, Minwan , LV, Wei , NGUYEN, Trung Xuan , DANG, Zhao , RAMAN, Krishnan
IPC分类号: C07D307/80 , C07D307/81 , A61K31/343
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公开(公告)号:EP4346806A2
公开(公告)日:2024-04-10
申请号:EP22811963.2
申请日:2022-05-24
发明人: KOTIAN, Pravin L. , BABU, Yarlagadda S. , ZHANG, Weihe , LV, Wei , LU, Peng-Cheng , SPAULDING, Andrew E. , RAMAN, Krishnan
IPC分类号: A61K31/417 , A61K31/4184 , A61K31/517
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公开(公告)号:EP4041238A1
公开(公告)日:2022-08-17
申请号:EP20874925.9
申请日:2020-10-09
发明人: KOTIAN, Pravin L. , BABU, Yarlagadda S. , ZHANG, Weihe , LU, Peng-Cheng , SPAULDING, Andrew E. , LV, Wei , DANG, Zhao , RAMAN, Krishnan
IPC分类号: A61K31/506 , A61K31/519 , A61K31/5377
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