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1.发明公开PHARMACEUTICAL PREPARATION CONTAINING MODIFICATIONS OF SURFACTANT PROTEIN B (SP-B) AND SURFACTANT PROTEIN C (SP-C) 审中-公开药物制备含表面活性剂蛋白B（SP-B）和表面活性蛋白C的修饰（SP-C）
公开(公告)号：EP1189625A1
公开(公告)日：2002-03-27
申请号：EP00938727.5
申请日：2000-06-02
IPC分类号： A61K38/17 , A61P11/00 , C07K14/785
CPC分类号： C07K14/785 , A61K9/0082 , A61K38/1709
摘要： The invention describes a novel pharmaceutical preparation for treating IRDS or ALI, comprising at least one modification of surfactant protein B (SP-B) and at least one modification of surfactant protein C (SP-C).
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2.发明公开COMPOSITIONS FOR THE TREATMENT OF ARDS OR IRDS CONTAINING 3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-4-PYRIDINYL)-4-(DIFLUOROMETHOXY)BENZAMIDE AND LUNG SURFACTANT 无效FOR治疗ARDS的组合物或IRDS 3-（CALCOPROPYLMETHOXY）-N-（3,5-二氯-4-吡啶基）-4-（二氟甲氧基）苯甲酰胺和肺表面活性剂CONTAIN
公开(公告)号：EP0977577A1
公开(公告)日：2000-02-09
申请号：EP98910670.3
申请日：1998-02-14
发明人： GERMANN, Paul-Georg , KILIAN, Ulrich , BEUME, Rolf , AMSCHLER, Hermann , KRÜGER, Uwe , HÄFNER, Dietrich , EISTETTER, Klaus
IPC分类号： A61K31/66
CPC分类号： A61K31/685 , A61K31/44 , A61K38/1709 , A61K45/06 , A61K2300/00
摘要： Composition for the treatment of infant or adult respiratory distress syndrome (IRDS and ARDS) contains N-(3,5-dichloropyrid-4-yl)-3- cyclopropylmethoxy-4- difluoromethoxybenzamide (II) (and/or its salts) and a lung surfactant.
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3.发明公开ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON IRDS UND ARDS, DIE MINDESTENS EIN GLUCOCORTICOSTEROID IN KOMBINATION MIT EINEM LUNGEN SURFACTANT ENTHALTEN 失效组合物治疗IRDS和ARDS至少一个糖皮质激素结合肺含有表面活性剂
公开(公告)号：EP0783314A2
公开(公告)日：1997-07-16
申请号：EP95935387.0
申请日：1995-09-27
CPC分类号： A61K35/42 , A61K38/1709 , A61K31/58 , A61K31/57 , A61K2300/00
摘要： Novel compositions are disclosed for the treatment of IRDS and ARDS, containing at least one glucocorticosteroid and a pulmonary surfactant. The duration of treatment and the mortality associated with these syndromes can be significantly reduced with the proposed novel compositions.
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4.发明公开COMBINATION OF C1-INH AND LUNG SURFACTANT FOR THE TREATMENT OF RESPIRATORY DISORDERS 审中-公开C1-INH组合以及治疗RESPIRATIONSTÖRUNGEN肺
公开(公告)号：EP1216052A1
公开(公告)日：2002-06-26
申请号：EP99947362.2
申请日：1999-09-16
申请人： Byk Gulden Lomberg Chemische Fabrik GmbH , Aventis Behring GmbH , Vangerow, Burkhard , Rückoldt, Horst , Marx, Gernot , Cobas Meyer, Michael , Leuwer, Martin
发明人： VANGEROW, Burkhard , RÜCKOLDT, Horst , MARX, Gernot , COBAS MEYER, Michael , LEUWER, Martin , HÄFNER, Dietrich , GERMANN, Paul-Georg , OTT, Nils
IPC分类号： A61K38/57 , A61K31/685 , A61K35/42 , A61K45/06 , A61P11/00
CPC分类号： A61K45/06 , A61K9/0082 , A61K31/66 , A61K38/02 , A61K38/57 , Y10T436/104165 , A61K2300/00
摘要： Pharmaceutical composition for the treatment of IRDS and ALI (including ARDS) which contains C1-INH (C1 esterase inhibitor) and lung surfactant.
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公开(公告)号：EP1131055A1
公开(公告)日：2001-09-12
申请号：EP99971701.0
申请日：1999-11-09
CPC分类号： A61K38/1709 , A61K9/0082
摘要： The invention describes a set for the treatment of IRDS, ALI or ARDS, comprising a first container which has a volume of 50 to 500 ml and contains a pulverulent pulmonary surfactant preparation, the amount of phospholipids in the container being 50 to 500 mg, and a second container which has a volume of 50 to 500 ml and contains a pulverulent pulmonary surfactant preparation, where the amount of phospholipids in the second container is 1 to 10 g.
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6.发明公开COMPOSITIONS COMPRISING PHENYLAMINOTHIOPHENACETIC ACID DERIVATIVES FOR THE TREATMENT OF ACUTE OR ADULT RESPIRATORY DISTRESS SYNDROME (ARDS) AND INFANT RESPIRATORY DISTRESS SYNDROME (IRDS) 有权制备含PHENYLAMINOTHIOPHENESSIGSÄURE的衍生物对急性呼吸功能不全（ARDS）和急性呼吸功能不全IN儿童的治疗（IRDS）
公开(公告)号：EP1098645A1
公开(公告)日：2001-05-16
申请号：EP99931116.0
申请日：1999-06-19
IPC分类号： A61K31/38
CPC分类号： A61K31/38
摘要： Novel compositions for the treatment of IRDS and ARDS are indicated which contain a compound of formula (I), in which R1 is hydrogen or 2-(2-hydroxyethoxy)ethyl and/or a pharmacologically tolerable salt of this compound and lung surfactant.
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