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1.发明公开SYSTEMS, METHODS, AND COMPOSITIONS FOR VIRAL-ASSOCIATED TUMORS 审中-公开SYSTEME，VERFAHREN UND ZUSAMMENSETZUNGENFÜRMIT VIREN ASSOZERERTE TUMORE
公开(公告)号：EP3049444A4
公开(公告)日：2017-06-07
申请号：EP14847881
申请日：2014-09-26
发明人： SANBORN JOHN ZACHARY , VASKE CHARLES JOSEPH , BENZ STEPHEN CHARLES , RABIZADEH SHAHROOZ , HENSLEY NICOLE , SOON-SHIONG PATRICK
CPC分类号： G06F19/22
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2.发明公开
公开(公告)号：EP3149641A4
公开(公告)日：2018-01-24
申请号：EP15799022
申请日：2015-06-01
发明人： RABIZADEH SHAHROOZ , SOON-SHIONG PATRICK , SANBORN JOHN ZACHARY , VASKE CHARLES JOSEPH , BENZ STEPHEN CHARLES
摘要： Omics patient data are analyzed using sequences or diff objects of tumor and matched normal tissue to identify patient and disease specific mutations, using transcriptomic data to identify expression levels of the mutated genes, and pathway analysis based on the so obtained omic data to identify specific pathway characteristics for the diseased tissue. Most notably, many different tumors have shared pathway characteristics, and identification of a pathway characteristic of a tumor may thus indicate effective treatment options ordinarily not considered when tumor analysis is based on anatomical tumor type only.
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公开(公告)号：EP2764460A4
公开(公告)日：2015-08-05
申请号：EP12838194
申请日：2012-10-06
申请人： NANT HOLDINGS IP LLC
CPC分类号： G06F19/322 , G06F19/3418 , G06Q50/22 , G16H10/60
摘要： Healthcare object (HCO) discriminator systems and methods are presented. Systems can obtain a digital representation of a scene via a sensor interface. An HCO discriminator platform analyzes the digital representation to discriminate objects within the scene as being associated with a type of HCO or as being unrelated to a type of HCO. Once the HCO recognition platform determines that a type of HCO is relevant, it instantiates an actual HCO. The HCO can be routed to one or more destinations based on routing rules generated from a template or based on the manner in which the objects in the scene were discriminated.
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4.发明公开SYSTEMS AND METHODS FOR LEARNING AND IDENTIFICATION OF REGULATORY INTERACTIONS IN BIOLOGICAL PATHWAYS 审中-公开系统和学习方法和生物信号用于识别调控性相互作用
公开(公告)号：EP2907039A4
公开(公告)日：2016-06-15
申请号：EP13846109
申请日：2013-10-09
申请人： FIVE3 GENOMICS LLC
CPC分类号： G06F19/12 , G06F19/24 , G06F19/3437 , G16H50/50
摘要： Contemplated systems and methods provide for machine learning and identification of regulatory interactions in biological pathways using a probabilistic graphical model, and especially for identification of interaction correlations among the regulatory parameters.
摘要翻译： 考虑的系统和方法提供一种用于机器学习和使用概率图形模型在生物途径调控性相互作用的鉴定，特别是对于爱的调节参数之间的相关性相互作用的鉴定。
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5.发明公开SYSTEMS AND METHODS FOR TRANSMISSION AND PRE-PROCESSING OF SEQUENCING DATA 审中-公开SYSTEME UND VERFAHREN ZURÜBERTRAGUNGUND VORVERARBEITUNG VON SEQUENZIERUNGSDATEN
公开(公告)号：EP3069285A4
公开(公告)日：2017-08-30
申请号：EP14862192
申请日：2014-11-13
申请人： FIVE3 GENOMICS LLC
CPC分类号： H04L67/06 , G06F17/30076 , G06F19/22 , G06F19/28
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公开(公告)号：EP2788770A4
公开(公告)日：2015-06-10
申请号：EP12854939
申请日：2012-12-07
申请人： FIVE3 GENOMICS LLC
IPC分类号： G01N33/574 , C12Q1/68 , G06F19/22 , G06F19/24
CPC分类号： C12Q1/6886 , C12Q1/6869 , C12Q2600/106 , C12Q2600/172 , G06F19/18 , G06F19/22 , G06F19/24 , G16H50/20
摘要： Contemplated systems and methods allow for computational genomic analysis using paired-end sequence analysis and split read refinement to thereby identify high-confidence breakpoints associated with high copy numbers and orientation of rearrangements, which is then the basis for full reconstruction of double minutes (DM). In especially preferred aspects, the DM will also include an oncogene or tumor suppressor gene, and/or may be found in blood or blood derived fluids.
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7.发明公开DISTRIBUTED SYSTEM PROVIDING DYNAMIC INDEXING AND VISUALIZATION OF GENOMIC DATA 审中-公开分布式面向动态索引和基因组数据的可视化
公开(公告)号：EP2788861A4
公开(公告)日：2015-04-15
申请号：EP12856007
申请日：2012-12-07
申请人： FIVE3 GENOMICS LLC
CPC分类号： G06T3/40 , G06F19/22 , G06F19/26 , G06F19/28 , G06T2200/24 , G09G5/373 , G09G2340/045 , G09G2354/00
摘要： Systems and methods for dynamic visualization of genomic data are provided in which a genomic visualization system adapts presentation of information content according to scale-relevant annotations within a sequence object.
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