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公开(公告)号：EP1868641A2
公开(公告)日：2007-12-26
申请号：EP06739529.3
申请日：2006-03-24
发明人： BARTH, Brenda , BHATIA, Ajay , ALDERSON, Mark , MAISONNEUVE, Jean-Francois L. , LOBET, Yves , NOZAY, Florence, Bernadette , MARCHAND, Martine , METTENS, Pascal , SKEIKY, Yasir A. , PROBST, Peter
IPC分类号： A61K39/118
CPC分类号： A61K39/118 , A61K2039/55572 , A61K2039/55577 , C07K14/295
摘要： The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention and diagnosis of Chlamydia infection.
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2.发明授权
公开(公告)号：EP1144642B1
公开(公告)日：2010-05-26
申请号：EP99963037.9
申请日：1999-12-08
申请人： CORIXA CORPORATION
发明人： PROBST, Peter , BHATIA, Ajay , SKEIKY, Yasir, A., W. , FLING, Steven, P. , JEN, Shyian , STROMBERG, Erica, Jean
IPC分类号： C12N15/31 , C07K14/295 , C12N1/21 , C12N1/19 , C12N5/10 , C07K19/00 , C12N15/62 , C07K16/02 , A61K39/118 , A61K31/70 , G01N33/569 , C12Q1/68 , A61K48/00
CPC分类号： C07K14/295 , A61K39/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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3.发明授权
公开(公告)号：EP1307564B1
公开(公告)日：2007-09-12
申请号：EP01959114.8
申请日：2001-07-20
申请人： CORIXA CORPORATION
IPC分类号： C12N15/31 , C12N15/62 , C12N15/63 , C12N5/10 , C07K14/295 , C07K16/12 , C12Q1/68 , G01N33/53 , A61K31/711 , A61K39/118 , A61K39/40
CPC分类号： C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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4.发明授权
公开(公告)号：EP1278855B1
公开(公告)日：2008-03-12
申请号：EP01928775.4
申请日：2001-04-23
申请人： CORIXA CORPORATION
IPC分类号： C12N15/31 , C07K14/295 , C12N15/63 , C07K16/12 , G01N33/68 , C07K19/00 , C12Q1/68 , A61K39/118 , A61K48/00 , C12N5/06 , A61K39/40 , G01N33/571
CPC分类号： C07K14/295 , A61K39/00 , A61K2039/505 , A61K2039/515 , A61K2039/5154 , A61K2039/5158 , A61K2039/53 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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5.发明公开
公开(公告)号：EP1581092A2
公开(公告)日：2005-10-05
申请号：EP02799875.6
申请日：2002-11-05
申请人： CORIXA CORPORATION
发明人： BHATIA, Ajay , GUDERIAN, Jeff , SKEIKY, Yasir, A., W. , MAISONNEUVE, Jean-Francois, L. , BARTH, Brenda , PROBST, Peter
IPC分类号： A61B1/00
CPC分类号： C12N5/0636 , A61K39/00 , A61K39/118 , A61K2035/124 , A61K2039/505 , A61K2039/515 , A61K2039/5154 , A61K2039/5158 , A61K2039/53 , A61K2039/57 , C07K14/295 , C07K2319/00 , G01N33/56927
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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6.发明授权
公开(公告)号：EP1287026B1
公开(公告)日：2005-11-23
申请号：EP01928377.9
申请日：2001-04-05
申请人： CORIXA CORPORATION
发明人： REED, Steven, G. , CAMPOS-NETO, Antonio , WEBB, John, R. , DILLON, Davin, C. , SKEIKY, Yasir, A., W. , BHATIA, Ajay , COLER, Rhea, M. , PROBST, Peter
CPC分类号： C07K14/44 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00 , Y02A50/41
摘要： Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
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7.发明公开
公开(公告)号：EP1287026A2
公开(公告)日：2003-03-05
申请号：EP01928377.9
申请日：2001-04-05
申请人： CORIXA CORPORATION
发明人： REED, Steven, G. , CAMPOS-NETO, Antonio , WEBB, John, R. , DILLON, Davin, C. , SKEIKY, Yasir, A., W. , BHATIA, Ajay , COLER, Rhea, M. , PROBST, Peter
IPC分类号： C07K14/44 , C12N15/30 , A61K39/008 , G01N33/569
CPC分类号： C07K14/44 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00 , Y02A50/41
摘要： Compositions and methods for preventing, treating and detecting leishmaniasis and stimulating immune responses in patients are disclosed. The compounds provided include polypeptides that contain at least an immunogenic portion of one or more Leishmania antigens, or a variant thereof. Vaccines and pharmaceutical compositions comprising such polypeptides, or polynucleotides encoding such polypeptides, are also provided and may be used, for example, for the prevention and therapy of leishmaniasis, as well as for the detection of Leishmania infection.
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8.发明公开
公开(公告)号：EP1238084A2
公开(公告)日：2002-09-11
申请号：EP00980969.0
申请日：2000-12-04
申请人： CORIXA CORPORATION
IPC分类号： C12N15/31 , C07K14/295 , C12N15/62 , C07K16/12 , A61K38/16 , A61K39/118 , A61K48/00 , G01N33/569 , C12Q1/68
CPC分类号： C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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9.发明公开
公开(公告)号：EP1144642A2
公开(公告)日：2001-10-17
申请号：EP99963037.9
申请日：1999-12-08
申请人： CORIXA CORPORATION
发明人： PROBST, Peter , BHATIA, Ajay , SKEIKY, Yasir, A., W. , FLING, Steven, P. , JEN, Shyian , STROMBERG, Erica, Jean
IPC分类号： C12N15/31 , C07K14/295 , C12N1/21 , C12N1/19 , C12N5/10 , C07K19/00 , C12N15/62 , C07K16/02 , A61K39/118 , A61K31/70 , G01N33/569 , C12Q1/68 , A61K48/00
CPC分类号： C07K14/295 , A61K39/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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10.发明公开
公开(公告)号：EP1307564A2
公开(公告)日：2003-05-07
申请号：EP01959114.8
申请日：2001-07-20
申请人： CORIXA CORPORATION
IPC分类号： C12N15/31 , C12N15/62 , C12N15/63 , C12N5/10 , C07K14/295 , C07K16/12 , C12Q1/68 , G01N33/53 , A61K31/711 , A61K39/118 , A61K39/40
CPC分类号： C07K14/295 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/51 , A61K2039/515 , A61K2039/5154 , A61K2039/53 , C07K2319/00
摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
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