VERWENDUNG VON ZUSAMMENSETZUNGEN ZUR PFLEGENDEN BEHANDLUNG DER HAUT
    6.
    发明公开
    VERWENDUNG VON ZUSAMMENSETZUNGEN ZUR PFLEGENDEN BEHANDLUNG DER HAUT 审中-公开
    局部用组合物含有硼酸衍生物于治疗皮肤干燥的

    公开(公告)号:EP1221948A2

    公开(公告)日:2002-07-17

    申请号:EP00971338.9

    申请日:2000-10-07

    IPC分类号: A61K31/00

    摘要: The invention relates to the use of compositions which represent a promising potential for the topical treatment of dry skin. Said compositions contain inhibitors in a physiologically compatible carrier which can be distributed on the skin. The inhibitors are used for the proteases that participate in the desmosome decomposition. The inhibitors contribute significantly to reduce desquamation processes and thus improve the appearance of the skin. Useful inhibitors can be boric acid and the derivatives thereof, 4-(2-amino-ethyl)phenyl sulfonyl fluoride (Pefabloc® and Pefabloc® SC), the pentapeptide sequence glycine-proline-phenylalanine-proline-leucine and the derivatives which contain said pentapeptide sequence, as well as rosemary acid and the active agent Elhibin® which is obtained from the leguminose seeds.