公开(公告)号：EP3391101A1

公开(公告)日：2018-10-24

申请号：EP16823342.7

申请日：2016-12-13

申请人： Novartis AG

发明人： QIAN, Xinming ,  NELSON, Jared ,  TUCKER, Robert Carey ,  ZHANG, Steve Yun ,  WU, Daqing ,  MUYA, Leroy Wainaina ,  PATEL, Dharmesh ,  MUNOZ, Zach ,  QIU, Yongxing ,  CHIANG, Chung-Yuan ,  SHRESTHA, Ritu ,  TALLAU, Kelly Kayi

IPC分类号： G02B1/04 ,  B29D11/00

摘要： The present invention generally relates to a method for producing silicone hydrogel contact lenses having a stable lubricious coating thereon without involving use of organic solvent in post-curing processes.

公开(公告)号：EP3516430A1

公开(公告)日：2019-07-31

申请号：EP17784392.7

申请日：2017-09-14

申请人： Novartis AG

发明人： QIU, Yongxing ,  PRUITT, John Dallas ,  NELSON, Jared

IPC分类号： G02B1/04 ,  B29D11/00

公开(公告)号：EP2368145B1

公开(公告)日：2018-07-11

申请号：EP09764424.9

申请日：2009-12-03

申请人： Novartis AG

发明人： PRUITT, John, Dallas ,  WINTERTON, Lynn, Cook ,  NELSON, Jared

IPC分类号： G02B1/04 ,  A61K9/00 ,  B29D11/00

CPC分类号： B29D11/00067 ,  A61K9/0051 ,  G02B1/043 ,  C08L51/085

摘要： The invention relates to a soft hydrogel contact lens, especially a silicone hydrogel contact lens, which has a capability of delivering a hydrophobic comfort agent into the eye of a wearer. The hydrophobic comfort agent includes without limitation a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, a phospholipid, a fatty acid, a fatty alcohol, a hydrocarbon having a C 12 -C 28 chain in length, a mineral oil, a silicone oil, or a mixture thereof. It can be released from the soft hydrogel contact lens into the eye of a wearer when being worn so as to strengthen and stabilize the tear film lipid layer and alleviate the dryness of the eye.

公开(公告)号：EP2461767B1

公开(公告)日：2013-05-08

申请号：EP11813220.8

申请日：2011-07-29

申请人： Novartis AG

发明人： QIU, Yongxing ,  PRUITT, John, Dallas ,  THEKVELI, Sibichen ,  TUCKER, Robert, Carey ,  NELSON, Jared

IPC分类号： A61F2/14 ,  G02B1/04 ,  G02C7/04

CPC分类号： C09D177/06 ,  B29D11/00067 ,  C08G77/388 ,  C08J5/00 ,  C08J7/042 ,  C08J2383/04 ,  C08J2383/08 ,  C08J2433/02 ,  C08J2433/26 ,  C08J2487/00 ,  C08L83/04 ,  C09D5/1637 ,  C09D5/1681 ,  C09D133/02 ,  C09D133/14 ,  C09D133/26 ,  C09D171/02 ,  G02B1/043 ,  G02B1/10 ,  G02B1/18 ,  G02C7/049 ,  G02C2202/06 ,  G02C2202/16 ,  C08L101/14

公开(公告)号：EP2368145A1

公开(公告)日：2011-09-28

申请号：EP09764424.9

申请日：2009-12-03

申请人： Novartis AG

发明人： PRUITT, John, Dallas ,  WINTERTON, Lynn, Cook ,  NELSON, Jared

IPC分类号： G02B1/04 ,  A61K9/00

CPC分类号： B29D11/00067 ,  A61K9/0051 ,  G02B1/043 ,  C08L51/085

摘要： The invention relates to a soft hydrogel contact lens, especially a silicone hydrogel contact lens, which has a capability of delivering a hydrophobic comfort agent into the eye of a wearer. The hydrophobic comfort agent includes without limitation a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, a phospholipid, a fatty acid, a fatty alcohol, a hydrocarbon having a C12-C28 chain in length, a mineral oil, a silicone oil, or a mixture thereof. It can be released from the soft hydrogel contact lens into the eye of a wearer when being worn so as to strengthen and stabilize the tear film lipid layer and alleviate the dryness of the eye.

公开(公告)号：EP3419966A1

公开(公告)日：2019-01-02

申请号：EP17709807.6

申请日：2017-02-16

申请人： Novartis AG

发明人： CHANG, Frank ,  DESOUSA, Ryan ,  HOLLAND, Troy Vernon ,  PRUITT, John Dallas ,  NELSON, Jared

IPC分类号： C07D249/20 ,  C07C233/37 ,  C08F20/36 ,  G02B5/20 ,  G02B5/22

摘要： Described herein are water-soluble UV-absorbing vinylic monomers and their uses in preparing UV-absorbing contact lenses capable of blocking ultra-violet (“UV”) radiation and optionally (but preferably) violet radiation with wavelengths from 380 nm to 440 nm, thereby protecting eyes to some extent from damages caused by UV radiation and potentially from violet radiation. This invention also provides a UV-absorbing contact lens.

公开(公告)号：EP3373047A1

公开(公告)日：2018-09-12

申请号：EP18169426.6

申请日：2009-12-03

申请人： Novartis AG

发明人： PRUITT, John Dallas ,  WINTERTON, Lynn Cook ,  NELSON, Jared

IPC分类号： G02B1/04 ,  A61K9/00 ,  B29D11/00

CPC分类号： B29D11/00067 ,  A61K9/0051 ,  G02B1/043 ,  C08L51/085

摘要： The invention relates to a soft hydrogel contact lens, especially a silicone hydrogel contact lens, which has a capability of delivering a hydrophobic comfort agent into the eye of a wearer. The hydrophobic comfort agent includes without limitation a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, a phospholipid, a fatty acid, a fatty alcohol, a hydrocarbon having a C 12 -C 28 chain in length, a mineral oil, a silicone oil, or a mixture thereof. It can be released from the soft hydrogel contact lens into the eye of a wearer when being worn so as to strengthen and stabilize the tear film lipid layer and alleviate the dryness of the eye.

公开(公告)号：EP2598938A1

公开(公告)日：2013-06-05

申请号：EP11813222.4

申请日：2011-07-29

申请人： Novartis AG

发明人： QIU, Yongxing ,  SAMUEL, Newton, T. ,  PRUITT, John, Dallas ,  KOLLURU, Chandana ,  MEDINA, Arturo, N. ,  WINTERTON, Lynn, Cook ,  WU, Daqing ,  QIAN, Xinming ,  NELSON, Jared

IPC分类号： G02C7/04 ,  B05D5/06 ,  B29D11/00

CPC分类号： C09D177/06 ,  B29D11/00067 ,  C08G77/388 ,  C08J5/00 ,  C08J7/042 ,  C08J2383/04 ,  C08J2383/08 ,  C08J2433/02 ,  C08J2433/26 ,  C08J2487/00 ,  C08L83/04 ,  C09D5/1637 ,  C09D5/1681 ,  C09D133/02 ,  C09D133/14 ,  C09D133/26 ,  C09D171/02 ,  G02B1/043 ,  G02B1/10 ,  G02B1/18 ,  G02C7/049 ,  G02C2202/06 ,  G02C2202/16 ,  C08L101/14

摘要： Hydrated silicone hydrogel contact lens having a layered structural configuration: a low water content silicone hydrogel core (or bulk material) completely covered with a layer of a water-rich (e.g., a water content greater than 80%), hydrogel totally or substantially free of silicone. The hydrated silicone hydrogel contact lens possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort.

摘要翻译： 具有层状结构构型的水合硅氧水凝胶隐形眼镜：完全被水富含层（例如，水含量大于80％）完全覆盖的低水含量的硅氧烷水凝胶核心（或散装材料），完全或基本上无水的水凝胶 的硅胶。 水合硅酮水凝胶隐形眼镜具有高透氧性，用于维持角膜健康和柔软，富含水分，光滑的表面，使佩戴舒适。

公开(公告)号：EP2461767A1

公开(公告)日：2012-06-13

申请号：EP11813220.8

申请日：2011-07-29

申请人： Novartis AG

发明人： QIU, Yongxing ,  PRUITT, John, Dallas ,  THEKVELI, Sibichen ,  TUCKER, Robert, Carey ,  NELSON, Jared

IPC分类号： A61F2/14

CPC分类号： C09D177/06 ,  B29D11/00067 ,  C08G77/388 ,  C08J5/00 ,  C08J7/042 ,  C08J2383/04 ,  C08J2383/08 ,  C08J2433/02 ,  C08J2433/26 ,  C08J2487/00 ,  C08L83/04 ,  C09D5/1637 ,  C09D5/1681 ,  C09D133/02 ,  C09D133/14 ,  C09D133/26 ,  C09D171/02 ,  G02B1/043 ,  G02B1/10 ,  G02B1/18 ,  G02C7/049 ,  G02C2202/06 ,  G02C2202/16 ,  C08L101/14

摘要： The invention is related to a hydrated silicone hydrogel contact lens having a layered structural configuration: a low water content silicone hydrogel core (or bulk material) completely covered with a layer of a water-rich (e.g., a water content greater than 80%), hydrogel totally or substantially free of silicone. A hydrated silicone hydrogel contact lens of the invention possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort.