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公开(公告)号：EP2109784B2
公开(公告)日：2016-10-05
申请号：EP08714067.9
申请日：2008-01-29
申请人： Novartis AG
发明人： QIU, Yongxing , QIAN, Xinming
IPC分类号： G02B1/04
CPC分类号： A61L27/18 , A61L12/088 , A61L27/54 , A61L2300/104 , A61L2300/404 , A61L2300/624 , A61L2400/12 , G02B1/043 , C08L43/04 , C08L83/04
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公开(公告)号：EP2598938A1
公开(公告)日：2013-06-05
申请号：EP11813222.4
申请日：2011-07-29
申请人： Novartis AG
发明人： QIU, Yongxing , SAMUEL, Newton, T. , PRUITT, John, Dallas , KOLLURU, Chandana , MEDINA, Arturo, N. , WINTERTON, Lynn, Cook , WU, Daqing , QIAN, Xinming , NELSON, Jared
CPC分类号： C09D177/06 , B29D11/00067 , C08G77/388 , C08J5/00 , C08J7/042 , C08J2383/04 , C08J2383/08 , C08J2433/02 , C08J2433/26 , C08J2487/00 , C08L83/04 , C09D5/1637 , C09D5/1681 , C09D133/02 , C09D133/14 , C09D133/26 , C09D171/02 , G02B1/043 , G02B1/10 , G02B1/18 , G02C7/049 , G02C2202/06 , G02C2202/16 , C08L101/14
摘要： Hydrated silicone hydrogel contact lens having a layered structural configuration: a low water content silicone hydrogel core (or bulk material) completely covered with a layer of a water-rich (e.g., a water content greater than 80%), hydrogel totally or substantially free of silicone. The hydrated silicone hydrogel contact lens possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort.
摘要翻译： 具有层状结构构型的水合硅氧水凝胶隐形眼镜：完全被水富含层（例如，水含量大于80％）完全覆盖的低水含量的硅氧烷水凝胶核心（或散装材料），完全或基本上无水的水凝胶 的硅胶。 水合硅酮水凝胶隐形眼镜具有高透氧性，用于维持角膜健康和柔软，富含水分，光滑的表面，使佩戴舒适。
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公开(公告)号：EP3420384A1
公开(公告)日：2019-01-02
申请号：EP17707124.8
申请日：2017-02-16
申请人： Novartis AG
发明人： CHANG, Frank , HOLLAND, Troy Vernon , QIAN, Xinming , SCOTT, Robert , LINDACHER, Joseph Michael , HAKEN, Uwe
IPC分类号： G02B1/04
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公开(公告)号：EP3344447A1
公开(公告)日：2018-07-11
申请号：EP16770798.3
申请日：2016-08-29
申请人： Novartis AG
发明人： QIAN, Xinming , CHANG, Frank , MATSUZAWA, Yasuo , SHANKAR, Venkat
IPC分类号： B29D11/00
摘要： The invention is related to a method for producing silicone hydrogel contact lenses with a stable lubricious hydrogel coating thereon. A method of the invention comprises forming a plasma-reactive hydrophilic polymer hybrid base coating having reactive functional groups on a silicone hydrogel contact lens and heating the silicone hydrogel contact lens with the hybrid base coating in an aqueous solution of a water-soluble and thermally crosslinkable hydrophilic polymeric material to form a stable lubricious hydrogel coating thereon.
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公开(公告)号：EP3344302A1
公开(公告)日：2018-07-11
申请号：EP16762875.9
申请日：2016-08-29
申请人： Novartis AG
发明人： QIAN, Xinming , CHANG, Frank , MATSUZAWA, Yasuo , SHANKAR, Venkat
CPC分类号： G02B1/043 , A61F2/14 , A61F2/1451 , A61F2/16 , A61F9/00781 , A61F2210/0061 , A61L12/04 , A61L27/18 , A61L27/34 , A61L2400/10 , A61L2400/18 , A61L2430/16 , C08L83/04
摘要： The invention is related to a medical device comprising a core material made of a crosslinked silicone material and a hydrogel coating which is thermodynamically stable. The invention is also related to a method for producing such a medical device, especially a soft contact lens.
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公开(公告)号：EP3391101A1
公开(公告)日：2018-10-24
申请号：EP16823342.7
申请日：2016-12-13
申请人： Novartis AG
发明人： QIAN, Xinming , NELSON, Jared , TUCKER, Robert Carey , ZHANG, Steve Yun , WU, Daqing , MUYA, Leroy Wainaina , PATEL, Dharmesh , MUNOZ, Zach , QIU, Yongxing , CHIANG, Chung-Yuan , SHRESTHA, Ritu , TALLAU, Kelly Kayi
摘要： The present invention generally relates to a method for producing silicone hydrogel contact lenses having a stable lubricious coating thereon without involving use of organic solvent in post-curing processes.
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公开(公告)号：EP2510051A1
公开(公告)日：2012-10-17
申请号：EP10836461.3
申请日：2010-12-06
申请人： Novartis AG
发明人： QIU, Yongxing , QIAN, Xinming
CPC分类号： G02B1/043 , C08L101/14
摘要： Described herein are methods for increasing the ion permeability of a silicone hydrogel contact lens by adding a small amount of an ion-permeability-enhancing ("IP-enhancing") hydrophilic vinylic monomer or macromer into a lens-forming material for cast-molding silicone hydrogel contact lenses, while not altering significantly the water content and/or the oxygen permeability of resultant lenses from the lens-forming material.
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公开(公告)号：EP2109784B1
公开(公告)日：2011-10-26
申请号：EP08714067.9
申请日：2008-01-29
申请人： Novartis AG
发明人： QIU, Yongxing , QIAN, Xinming
IPC分类号： G02B1/04
CPC分类号： A61L27/18 , A61L12/088 , A61L27/54 , A61L2300/104 , A61L2300/404 , A61L2300/624 , A61L2400/12 , G02B1/043 , C08L43/04 , C08L83/04
摘要： Methods for making an antimicrobial medical device, preferably an antimicrobial ophthalmic device, more preferably an antimicrobial extended-wear contact lens, which contains chloride-treated silver nanoparticles distributed uniformly therein. The antimicrobial medical device can exhibit antimicrobial activity over an extended period of time but is substantially free of the characteristic yellowish color of the untreated silver nanoparticles.
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公开(公告)号：EP2109784A1
公开(公告)日：2009-10-21
申请号：EP08714067.9
申请日：2008-01-29
申请人： Novartis AG
发明人： QIU, Yongxing , QIAN, Xinming
IPC分类号： G02B1/04
CPC分类号： A61L27/18 , A61L12/088 , A61L27/54 , A61L2300/104 , A61L2300/404 , A61L2300/624 , A61L2400/12 , G02B1/043 , C08L43/04 , C08L83/04
摘要： Methods for making an antimicrobial medical device, preferably an antimicrobial ophthalmic device, more preferably an antimicrobial extended-wear contact lens, which contains chloride-treated silver nanoparticles distributed uniformly therein. The antimicrobial medical device can exhibit antimicrobial activity over an extended period of time but is substantially free of the characteristic yellowish color of the untreated silver nanoparticles.
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公开(公告)号：EP3344447B1
公开(公告)日：2019-12-11
申请号：EP16770798.3
申请日：2016-08-29
申请人： Novartis AG
发明人： QIAN, Xinming , CHANG, Frank , MATSUZAWA, Yasuo , SHANKAR, Venkat
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