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1.发明公开
公开(公告)号：EP1390368A1
公开(公告)日：2004-02-25
申请号：EP01947360.2
申请日：2001-06-08
发明人： BARGIOTTI, Alberto , ERMOLI, Antonella , MENICHINCHERI, Maria , VANOTTI, Ermes , BONOMINI, Luisella , FRETTA, Antonella
IPC分类号： C07D473/18 , A61K31/52 , A61P35/00
CPC分类号： C07D473/18
摘要： The present invention relates to benzylmethyl and/or naphtylmethyl disubstituted 7,9-guaninium halides possessing antitumor activity, to pharmaceutical compositions comprising them and to a process for preparing the same. Furthermore, these compounds are expected to enhance the efficacy of other chemotherapeutic agents, in the treatment of cancer.
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2.发明授权DISUBSTITUTED 7,9-GUANINIUM HALIDES AS TELOMERASE INHIBITORS 有权DISUBSTITUIERTE 7,9-KANIUMI ALA TELOMERASEINHIBITOREN
公开(公告)号：EP1390368B1
公开(公告)日：2005-10-26
申请号：EP01947360.2
申请日：2001-06-08
发明人： BARGIOTTI, Alberto , ERMOLI, Antonella , MENICHINCHERI, Maria , VANOTTI, Ermes , BONOMINI, Luisella , FRETTA, Antonella
IPC分类号： C07D473/18 , A61K31/52 , A61P35/00
CPC分类号： C07D473/18
摘要： The present invention relates to benzylmethyl and/or naphtylmethyl disubstituted 7,9-guaninium halides possessing antitumor activity, to pharmaceutical compositions comprising them and to a process for preparing the same. Furthermore, these compounds are expected to enhance the efficacy of other chemotherapeutic agents, in the treatment of cancer.
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公开(公告)号：EP1381359A1
公开(公告)日：2004-01-21
申请号：EP02727562.7
申请日：2002-04-15
发明人： BALLINARI, Dario , BONOMINI, Luisella , ERMOLI, Antonella , GUDE, Markus , MENICHINCHERI, Maria , MOLL, Jurgen , VANOTTI, Ermes
IPC分类号： A61K31/34 , C07D307/86 , A61P35/00
CPC分类号： C07D405/06 , A61K31/343 , A61K45/06 , C07D307/86 , C07D407/06 , C07D409/06 , A61K2300/00
摘要： The present invention relates to know and novel substituted aurones active as telomerase inhibitors, to their use as therapeutic agents, in particular as antitumoral agents, to a process for their preparation as to pharmaceutical compositions comprising them.
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公开(公告)号：EP1383766A1
公开(公告)日：2004-01-28
申请号：EP01960299.4
申请日：2001-06-08
发明人： BARGIOTTI, Alberto , ERMOLI, Antonella , MENICHINCHERI, Maria , VANOTTI, Ermes , BONOMINI, Luisella , FRETTA, Antonella
IPC分类号： C07D473/18 , A61K31/32
CPC分类号： C07D473/18 , A61K31/522
摘要： The present invention relates to 1,7 disubstituted guanines inhibitors possessing antitumor activity and to a process for preparing the same. Furthermore, these compounds are expected to enhance the efficacy of other chemotherapeutic agents, in the treatment of cancer.
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公开(公告)号：EP1373244A2
公开(公告)日：2004-01-02
申请号：EP02732481.3
申请日：2002-03-12
发明人： BARGIOTTI, Alberto , BONOMINI, Luisella , MENICHINCHERI, Maria , MOLL, Jurgen , POLUCCI, Paolo , SONCINI, Chiara , VANOTTI, Ermes
IPC分类号： C07D311/30 , C07F7/18 , A61K31/35
CPC分类号： C07D405/04 , A61K31/352 , C07D311/30 , C07D413/04 , C07D417/04
摘要： The present invention relates to benzopyranone derivative, to methods for treating telomerase-modulated diseases, in particular cancers, with said derivatives, to a process for their preparation, to their use as medicaments and to pharmaceutical compositions comprising them.
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