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21 条记录 (耗时 0.012 秒)

    METHOD FOR THE PURIFICATION OF AN ALPHA-HYDROXY ACID ON AN INDUSTRIAL SCALE
    2.
    发明授权
    METHOD FOR THE PURIFICATION OF AN ALPHA-HYDROXY ACID ON AN INDUSTRIAL SCALE 有权
    方法用于清洁α-羟基ON工业基地

    公开(公告)号：EP1317409B2

    公开(公告)日：2011-07-27

    申请号：EP01981151.2

    申请日：2001-09-14

    申请人： Purac Biochem B.V.

    发明人： VAN KRIEKEN, Jan ,  VAN BREUGEL, Jan

    IPC分类号： C07C51/43 ,  C07C51/44 ,  C07C59/06 ,  C07C59/08 ,  C07C51/48 ,  A61K31/19

    CPC分类号： C07C51/44 ,  C07C51/43 ,  C07C51/48 ,  C07C59/06 ,  C07C59/08

    摘要： The present invention relates to a method for the purification of an α-hydroxy acid on an industrial scale, in which the method involves: (a) subjecting an aqueous stream containing mainly α-hydroxy acid (1) to an extraction step, with the formation of an aqueous place containing mainly α-hydroxy acid (2), (b) concentrating the aqueous phase containing mainly α-hydroxy acid (2) by means of evaporation of water under reduced pressure, with the formation of a concentrated α-hydroxy acid solution in water (3), and (c) subjecting the concentrated α-hydroxy acid solution (3) to a crystallization, with formation of pure α-hydroxy acid (4), where (i) the concentrated α-hydroxy acid solution (3) is directly cooled in a melting crystallization device, and/or (ii) the concentrated α-hydroxy acid solution (3) is diluted with water and crystallization is brought about in one or more cooling crystallization devices and/or evaporative crystallization devices, and/or (iii) crystallization is brought about in one or more adiabatic crystallization devices.

    METHOD FOR THE PURIFICATION OF AN ALPHA-HYDROXY ACID ON AN INDUSTRIAL SCALE
    3.
    发明授权
    METHOD FOR THE PURIFICATION OF AN ALPHA-HYDROXY ACID ON AN INDUSTRIAL SCALE 有权
    方法用于清洁α-羟基ON工业基地

    公开(公告)号：EP1317409B1

    公开(公告)日：2008-02-27

    申请号：EP01981151.2

    申请日：2001-09-14

    申请人： Purac Biochem B.V.

    发明人： VAN KRIEKEN, Jan ,  VAN BREUGEL, Jan

    IPC分类号： C07C51/43 ,  C07C51/44 ,  C07C59/06 ,  C07C59/08 ,  C07C51/48 ,  A61K31/19

    CPC分类号： C07C51/44 ,  C07C51/43 ,  C07C51/48 ,  C07C59/06 ,  C07C59/08

    摘要： The present invention relates to a method for the purification of an α-hydroxy acid on an industrial scale, in which the method involves: (a) subjecting an aqueous stream containing mainly α-hydroxy acid (1) to an extraction step, with the formation of an aqueous place containing mainly α-hydroxy acid (2), (b) concentrating the aqueous phase containing mainly α-hydroxy acid (2) by means of evaporation of water under reduced pressure, with the formation of a concentrated α-hydroxy acid solution in water (3), and (c) subjecting the concentrated α-hydroxy acid solution (3) to a crystallization, with formation of pure α-hydroxy acid (4), where (i) the concentrated α-hydroxy acid solution (3) is directly cooled in a melting crystallization device, and/or (ii) the concentrated α-hydroxy acid solution (3) is diluted with water and crystallization is brought about in one or more cooling crystallization devices and/or evaporative crystallization devices, and/or (iii) crystallization is brought about in one or more adiabatic crystallization devices.

    METHOD FOR MANUFACTURING SUCCINIC ACID ESTERS
    6.
    发明公开
    METHOD FOR MANUFACTURING SUCCINIC ACID ESTERS 审中-公开
    用于生产丁二酸酯

    公开(公告)号：EP2956435A1

    公开(公告)日：2015-12-23

    申请号：EP14704775.7

    申请日：2014-02-13

    申请人： Purac Biochem B.V.

    发明人： VAN KRIEKEN, Jan ,  DE HAAN, André Banier ,  VAN BREUGEL, Jan

    IPC分类号： C07C67/08 ,  C07C69/40

    CPC分类号： C07C29/095 ,  C07C29/149 ,  C07C67/08 ,  C07C67/38 ,  C12P7/62 ,  C07C69/68

    摘要： The invention pertains to a process for for preparing a succinic acid ester comprising the steps of - bringing an aqueous liquid comprising succinic acid, alcohol, and at least 5 wt. % of a dissolved chloride salt selected from magnesium chloride, calcium chloride, and zinc chloride, calculated on the weight of the liquid, to reaction conditions, thereby obtaining a succinic acid ester, and - recovering the succinic acid ester and an aqueous solution comprising the dissolved chloride salt. It has been found that the process according to the invention shows a high yield and has a high reaction rate. Additionally, it has been found that the process makes it possible to carry out the separation of the succinic acid ester from the aqueous reaction medium in high yield.

    METHOD FOR ISOLATING A CARBOXYLIC ACID FROM AN AQUEOUS SOLUTION
    7.
    发明公开
    METHOD FOR ISOLATING A CARBOXYLIC ACID FROM AN AQUEOUS SOLUTION 有权
    VERFAHREN ZUR ISOLIERUNG EINERCARBONSÄUREAUS EINER WASSERHALTIGERLÖSUNG

    公开(公告)号：EP2794049A1

    公开(公告)日：2014-10-29

    申请号：EP12806504.2

    申请日：2012-12-21

    申请人： Purac Biochem B.V.

    发明人： DE HAAN, André Banier ,  VAN KRIEKEN, Jan ,  ÐEKIC IVKOVIC, Tanja

    IPC分类号： B01D11/04 ,  C07C51/48 ,  C07C55/10 ,  C07C57/13 ,  C07C57/15 ,  C07C59/01 ,  C07C59/06 ,  C07C59/08 ,  C12P7/00

    CPC分类号： C07C51/48 ,  B01D11/04 ,  B01D11/0426 ,  C07C51/412 ,  C12P7/56 ,  C07C55/10 ,  C07C57/13 ,  C07C57/15

    摘要： A method for recovering lactic acid from an aqueous mixture including the steps of: providing an aqueous mixture including lactic acid and at least 5 wt. % dissolved magnesium chloride, based on the total weight of water and dissolved material in the aqueous mixture; extracting the lactic acid from the aqueous mixture into a first organic liquid including an organic solvent selected from the group consisting of C5+ ketones, diethylether and methyl-tertiary-butyl-ether, thereby obtaining an organic lactic acid solution and an aqueous waste liquid including magnesium chloride; and extracting the lactic acid from the organic lactic acid solution into an aqueous liquid, thereby obtaining an aqueous lactic acid solution and a second organic liquid. The method according to the invention allows a combined purification and concentration step for feed solutions of lactic acid.

    摘要翻译： 一种从水性混合物中回收乳酸的方法，包括以下步骤：提供包含乳酸和至少5wt。 基于水和混合物中溶解的材料的总重量，溶解的氯化镁百分比; 将含水混合物中的乳酸从含有C5 +酮，二乙醚，甲基叔丁基醚的有机溶剂构成的第一有机液中提取出来，得到有机乳酸溶液和含有镁的水性废液 氯化物; 并将乳酸从有机乳酸溶液中提取到水性液体中，由此得到乳酸水溶液和第二有机液体。 根据本发明的方法允许乳酸进料溶液的组合纯化和浓缩步骤。