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1.发明公开TANKYRASE H, COMPOSITIONS INVOLVED IN THE CELL CYCLE AND METHODS OF USE 审中-公开端锚聚合酶为h，它与细胞周期是否涉及组合物及其用途
公开(公告)号：EP1238063A2
公开(公告)日：2002-09-11
申请号：EP00988503.9
申请日：2000-10-25
发明人： LUO, Ying , CHAN, Eva , XU, Xiang , HUANG, Betty , OSSOVSKAYA, Valeria
CPC分类号： C12N9/1077 , A61K38/00 , C12N2310/111
摘要： The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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2.发明公开
公开(公告)号：EP1222267A2
公开(公告)日：2002-07-17
申请号：EP00966820.3
申请日：2000-09-22
发明人： LUO, Ying , HUANG, Betty
CPC分类号： C07K14/47 , C07K14/4738
摘要： The present invention is directed to polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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3.发明授权ING2, AN IAPS ASSOCIATED CELL CYCLE PROTEIN, COMPOSITIONS AND METHODS OF USE 有权ING2，一个有IAPS相关的细胞周期蛋白和组合物，方法和用途
公开(公告)号：EP1237916B1
公开(公告)日：2005-03-09
申请号：EP00979200.3
申请日：2000-11-17
发明人： LUO, Ying , XU, Xiang , LEO, Cindy , HUANG, Betty , SHEN, Mary
IPC分类号： C07K14/47
CPC分类号： C07K14/4747 , A61K38/00
摘要： The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also, provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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公开(公告)号：EP1238064A2
公开(公告)日：2002-09-11
申请号：EP00978757.3
申请日：2000-11-16
发明人： LUO, Ying , YU, PeiWen , SHEN, Mary , HUANG, Betty
IPC分类号： C12N9/12
CPC分类号： C12N9/1205 , C07K14/4738 , C07K16/18
摘要： The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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公开(公告)号：EP1056855A2
公开(公告)日：2000-12-06
申请号：EP99908382.7
申请日：1999-02-23
发明人： FISHER, Joseph , LORENS, James , ANDERSON, David , LUO, Ying , HUANG, Betty , SHEN, Mary
CPC分类号： C07K14/4703
摘要： The present invention is directed to novel exocytotic polypeptides, such as Exo1 and Exo2 polypeptides and related molecules, which have an inhibitory effect on exocytosis and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate exocytotic polypeptide bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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6.发明公开ING2, AN IAPS ASSOCIATED CELL CYCLE PROTEIN, COMPOSITIONS AND METHODS OF USE 有权ING2，一个有IAPS相关的细胞周期蛋白和组合物，方法和用途
公开(公告)号：EP1237916A2
公开(公告)日：2002-09-11
申请号：EP00979200.3
申请日：2000-11-17
发明人： LUO, Ying , XU, Xiang , LEO, Cindy , HUANG, Betty , SHEN, Mary
IPC分类号： C07K14/47
CPC分类号： C07K14/4747 , A61K38/00
摘要： The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also, provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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7.发明公开P15PAF CELL CYCLE PROTEINS ASSOCIATED WITH PCNA, COMPOSITIONS AND METHODS OF USE 审中-公开随着相关PCNA P15 PAF细胞周期蛋白，组成和方法及其用途
公开(公告)号：EP1224470A2
公开(公告)日：2002-07-24
申请号：EP00984557.9
申请日：2000-10-18
发明人： LUO, Ying , YU, PeiWen , HUANG, Betty
IPC分类号： G01N33/68 , G01N33/50 , C07K16/18 , G01N33/574
CPC分类号： C07K14/4738
摘要： The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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8.发明公开
公开(公告)号：EP1222211A1
公开(公告)日：2002-07-17
申请号：EP00966817.9
申请日：2000-09-22
发明人： LUO, Ying , HUANG, Betty
IPC分类号： C07K16/40 , C12N9/22 , G01N33/566
CPC分类号： C07K16/40 , G01N33/5011
摘要： The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
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