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公开(公告)号:EP4011911A1
公开(公告)日:2022-06-15
申请号:EP21204045.5
申请日:2016-11-03
申请人: The United States of America as represented by The Secretary Department of Health and Human Services , The Trustees of Columbia University in the City of New York
发明人: KWONG, Peter , KWON, Young Do , GEORGIEV, Ivelin , OFEK, Gilad , ZHANG, Baoshan , MCKEE, Krisha , MACSOLA, John , CHUANG, Gwo-Yu , O'DELL, Sijy , GINDIN, Tatyana , SHAPIRO, Lawrence , BAILER, Robert , LOUDER, Mark , ASOKAN, Mangaiarkarasi , SCHWARTZ, Richard , COOPER, Jonathan , CARLTON, Kevin , BENDER, Michael , CONNORS, Mark , PEGU, Amarendra , KUELTZO, Lisa
IPC分类号: C07K16/10
摘要: Neutralizing antibodies that specifically bind to HIV-1 Env and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.
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公开(公告)号:EP3371214A1
公开(公告)日:2018-09-12
申请号:EP16801639.2
申请日:2016-11-03
申请人: THE UNITED STATES OF AMERICA, represented by the S , The Trustees of Columbia University in the City of New York
发明人: KWONG, Peter , KWON, Young, Do , GEORGIEV, Ivelin , OFEK, Gilad , ZHANG, Baoshan , MCKEE, Krisha , MACSOLA, John , CHUANG, Gwo-Yu , O'DELL, Sijy , GINDIN, Tatyana , SHAPIRO, Lawrence , BAILER, Robert , LOUDER, Mark , ASOKAN, Mangaiarkarasi , SCHWARTZ, Richard , COOPER, Jonathan , CARLTON, Kevin , BENDER, Michael , CONNORS, Mark , PEGU, Amarendra , KUELTZO, Lisa
IPC分类号: C07K16/10
CPC分类号: C07K16/1063 , C07K2317/21 , C07K2317/33 , C07K2317/52 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: Neutralizing antibodies that specifically bind to HIV-1 Env and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed.
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