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公开(公告)号:EP4377486A1
公开(公告)日:2024-06-05
申请号:EP22751424.7
申请日:2022-07-21
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2.
公开(公告)号:EP4301729A1
公开(公告)日:2024-01-10
申请号:EP22712964.0
申请日:2022-03-04
IPC分类号: C07C319/20 , C07C323/60 , C07C323/58
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3.
公开(公告)号:EP3772962B9
公开(公告)日:2023-07-19
申请号:EP19715686.2
申请日:2019-03-21
发明人: MARTIN, Timothy P. , ROSS, Ronald, Jr. , HEEMSTRA, Ronald J. , ECKELBARGER, Joseph D. , TRULLINGER, Tony K. , HUNTER, Ricky , WALSH, Martin J.
IPC分类号: A01N53/00 , C07C317/44 , C07C323/60
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公开(公告)号:EP4129976A1
公开(公告)日:2023-02-08
申请号:EP21781393.0
申请日:2021-03-24
IPC分类号: C07C319/24 , C07C323/58 , C07C323/59 , C07C323/60 , C07D341/00
摘要: Disclosed is a method for producing a trisulfide compound or a selenotrisulfide compound. This production method includes: a step for oxidizing a disulfide compound with an oxidizing agent to obtain a sulfoxide compound; and a step for reacting the sulfoxide compound that has been obtained with a source of sulfur or a source of selenium to obtain a trisulfide compound or a selenotrisulfide compound.
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公开(公告)号:EP3921305A1
公开(公告)日:2021-12-15
申请号:EP20702140.3
申请日:2020-02-03
发明人: BILZ, Jürgen , BORGMANN, Cornelia , GEIST, Lucas , JAKOB, Harald , KÖRFER, Martin , REUS, Christian , ROST, Daniel
IPC分类号: C07C319/20 , C07C319/28 , C07C323/58 , C07C323/60 , B01J23/00 , B01J35/02 , B01J21/06
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公开(公告)号:EP3921304A1
公开(公告)日:2021-12-15
申请号:EP20702136.1
申请日:2020-02-03
发明人: BILZ, Jürgen , BORGMANN, Cornelia , FISCHER, Achim , GEIST, Lucas , NORDSCHILD, Anja , RENNER, Christian , REUS, Christian , RONNEBURG, Axel
IPC分类号: C07C319/20 , C07C323/60
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公开(公告)号:EP3838893A1
公开(公告)日:2021-06-23
申请号:EP19849476.7
申请日:2019-08-15
发明人: ZHOU, Xinbo , WANG, Yanming , FAN, Shiyong , LI, Song , ZHONG, Wu , XIAO, Junhai , ZHENG, Zhibing , LI, Xingzhou , XIAO, Dian , XIE, Yunde , WANG, Xiaokui , CAO, Ruiyuan
IPC分类号: C07D207/416 , C07D207/46 , C07C323/60 , C07C323/52 , A61K31/4015 , A61K31/337 , C07K5/093 , A61K47/68 , A61P3/00 , A61P7/00 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02
摘要: Provided are a linker represented by Formula I or I', an antibody-drug conjugate containing the same, and use of thereof, a pharmaceutical composition comprising the antibody-drug conjugate, and use of the antibody-drug conjugate for treating and/or preventing a disease.
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8.
公开(公告)号:EP3772962A1
公开(公告)日:2021-02-17
申请号:EP19715686.2
申请日:2019-03-21
发明人: MARTIN, Timothy P. , ROSS, Ronald, Jr. , HEEMSTRA, Ronald J. , ECKELBARGER, Joseph D. , TRULLINGER, Tony K. , HUNTER, Ricky , WALSH, Martin J.
IPC分类号: A01N53/00 , C07C317/44 , C07C323/60
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公开(公告)号:EP3122342B1
公开(公告)日:2020-09-23
申请号:EP15770142.6
申请日:2015-03-27
IPC分类号: C07C319/12 , C07C323/59 , C07C323/60 , A61K31/095 , A61K31/16 , A61K31/195 , A61K31/198 , A61K38/04
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公开(公告)号:EP3018125B1
公开(公告)日:2020-08-05
申请号:EP14819450.9
申请日:2014-06-30
IPC分类号: C07C323/60 , A61K31/427 , A61K31/44 , A61P25/24 , A61P43/00 , C07D207/42 , C07D213/64 , C07D213/75 , C07D277/20 , C07D277/26 , C07D277/42 , C07D401/12 , C07D403/12 , C07D417/12 , C07D417/14
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