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公开(公告)号:EP2661450A4
公开(公告)日:2014-04-23
申请号:EP12732149
申请日:2012-01-06
申请人: DYAX CORP
发明人: SEXTON DANIEL J
IPC分类号: A61K39/395 , C07K16/18 , C07K16/40
CPC分类号: C07K16/40 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/573 , G01N2333/96455 , G01N2500/04
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公开(公告)号:EP2661450A1
公开(公告)日:2013-11-13
申请号:EP12732149.5
申请日:2012-01-06
申请人: Dyax Corp.
发明人: SEXTON, Daniel, J.
IPC分类号: C07K16/36 , A61K39/395
CPC分类号: C07K16/40 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/573 , G01N2333/96455 , G01N2500/04
摘要: Plasma kallikrein binding proteins and methods of using such proteins are described.
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公开(公告)号:EP1761562B1
公开(公告)日:2013-09-11
申请号:EP05723364.5
申请日:2005-02-22
申请人: Dyax Corp.
IPC分类号: A61K39/395 , C07K16/46 , C07K16/28 , C07K16/00
CPC分类号: C07K16/2845 , A61K2039/505 , C07K2317/32 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
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公开(公告)号:EP2262529A4
公开(公告)日:2013-05-08
申请号:EP09716600
申请日:2009-03-03
申请人: DYAX CORP
发明人: DEVY LAETITIA , BUCKLER DAVID , COHEN EDWARD H
IPC分类号: A61K39/395 , C07K16/40
CPC分类号: C07K16/40 , A61K2039/505 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
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公开(公告)号:EP2385843A4
公开(公告)日:2013-02-27
申请号:EP10729465
申请日:2010-01-06
申请人: DYAX CORP
发明人: STERNLICHT ANDREW
IPC分类号: A61K39/395 , A61K38/16 , A61P1/04
CPC分类号: A61K38/16 , C07K16/40 , C07K2317/565 , C07K2317/76 , C07K2317/92
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公开(公告)号:EP1812049A4
公开(公告)日:2012-12-26
申请号:EP05799587
申请日:2005-09-22
申请人: DYAX CORP
发明人: LADNER ROBERT C , LEY ARTHUR C , HIRANI SHIRISH , WILLIAMS ANTHONY , DE SIMONI MARIA GRAZIA , BERGAMASCHINI LUIGI , BLAIR HENRY , BECK THOMAS
IPC分类号: A61K38/17 , A61K31/195 , A61K38/48 , A61K38/55 , A61K45/06
CPC分类号: A61K38/55 , A61K31/195 , A61K38/57 , A61K45/06 , A61K2300/00
摘要: There is provided a composition comprising an inhibitor of plasma kallikrein for use in treating brain injury caused by cerebral ischemia in a patient, wherein the inhibitor of plasma kallikrein comprises a non-naturally occurring polypeptide comprising residues 3-60 of SEQ ID NO: 2.
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97.Methods of constructing display libraries of genetic packages for members of a diverse family of peptides 有权
标题翻译: 有关建立肽不同家庭的基因包库的过程公开(公告)号:EP2199393B1
公开(公告)日:2012-10-31
申请号:EP10156326.0
申请日:2001-04-17
申请人: Dyax Corp.
发明人: Ladner, Robert, C. , Cohen, Edward, Hirsch , Nastri, Horacio, Gabriel , Rookey, Kristin, L. , Hoet, Rene
CPC分类号: C12N15/1093 , C12N15/10 , C12N15/1037 , C12N15/66 , C40B40/02
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公开(公告)号:EP1542710B1
公开(公告)日:2012-09-26
申请号:EP03791557.6
申请日:2003-06-06
申请人: Dyax Corp.
IPC分类号: A61K38/00
CPC分类号: A01N1/02 , A01N1/0226
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99.
公开(公告)号:EP2478136A2
公开(公告)日:2012-07-25
申请号:EP10816294.2
申请日:2010-09-14
申请人: Dyax Corp.
发明人: LADNER, Robert, C.
IPC分类号: C40B40/08
CPC分类号: C07K16/005 , C07K2317/21 , C07K2317/565
摘要: Provided are compositions and methods for preparing and identifying antibodies having CDR3s that vary in sequence and in length from very short to very long. Libraries encoding antibodies with the CDR3s are also provided. The libraries can be provided by modifying a pre-existing nucleic acid library.
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100.USE OF IGF-II/IGF-IIE BINDING FOR THE TREATMENT AND PREVENTION OF SYSTEMIC SCLEROSIS ASSOCIATED PULMONARY FIBROSIS 审中-公开
标题翻译: IGF-II的使用/ IGF-IIE约束力用于治疗和预防系统性硬化症时相关的肺纤维变性公开(公告)号:EP2349329A1
公开(公告)日:2011-08-03
申请号:EP09821171.7
申请日:2009-10-14
申请人: Dyax Corp.
发明人: COHEN, Edward, H.
IPC分类号: A61K39/395
CPC分类号: C07K16/22 , C07K14/65 , C07K2317/55 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: Methods of using proteins that bind to IGF-II and/or IGF-IIE for the treatment or prevention of systemic sclerosis-associated pulmonary fibrosis are described.
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