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公开(公告)号：EP3850335A1
公开(公告)日：2021-07-21
申请号：EP18773128.6
申请日：2018-09-14
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92.发明公开
公开(公告)号：EP3762423A2
公开(公告)日：2021-01-13
申请号：EP19713707.8
申请日：2019-03-06
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93.发明公开
公开(公告)号：EP3699197A1
公开(公告)日：2020-08-26
申请号：EP20165971.1
申请日：2016-11-09
IPC分类号： C07K16/28 , C07K14/705
摘要： The present invention relates to a novel molecule comprising three binding sites with specificity for a tumor cell, for an effector cell and for a checkpoint molecule, respectively. Moreover, the present invention relates to a pharmaceutical composition comprising such a molecule and to uses of such a molecule.
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94.发明公开
公开(公告)号：EP3634403A1
公开(公告)日：2020-04-15
申请号：EP18722077.7
申请日：2018-05-11
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. , Ludwig-Maximilians-Universität München , Georg-August-Universität Göttingen
发明人： BECKER, Dorothea , JOVIN, Thomas M. , GRIESINGER, Christian , LEONOV, Andrei , RYAZANOV, Sergey , GIESE, Armin , OUTEIRO, Tiago F. , LAZARO, Diana F. , SCHÖN, Michael P. , SCHÖN, Margarete
IPC分类号： A61K31/415 , A61K31/4155 , A61K31/675 , A61P35/00
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95.发明授权
公开(公告)号：EP2809682B1
公开(公告)日：2020-04-08
申请号：EP13705405.2
申请日：2013-01-24
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公开(公告)号：EP3577466A1
公开(公告)日：2019-12-11
申请号：EP18703293.3
申请日：2018-01-31
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97.发明公开
公开(公告)号：EP3518354A1
公开(公告)日：2019-07-31
申请号：EP18153450.4
申请日：2018-01-25
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. , Ludwig-Maximilians-Universität München
IPC分类号： H01S3/098 , H01S3/13 , H01S3/00 , H01S3/06 , H01S3/08 , H01S3/081 , H01S3/094 , H01S3/106 , H01S3/107 , H01S3/136 , H01S3/16
摘要： A laser device (100), being configured for generating laser pulses by Kerr lens based mode locking, comprises a laser resonator (10) with a plurality of resonator mirrors (11.1, 11.2, 11.3) spanning a resonator beam path (12), a solid state gain medium (20) being arranged in the laser resonator (10), a Kerr medium device (30) being arranged with a distance from the gain medium (20) in the laser resonator (10), wherein the Kerr medium device (30) includes at least one Kerr medium being arranged in a focal range of the resonator beam path and being configured for forming the laser pulses by the nonlinear Kerr effect, and a loss-modulation device (31, 32) having a modulator medium, which is capable of modulating a power loss of the laser pulses generated in the laser resonator (10), wherein the Kerr medium device (30) includes the modulator medium of the loss-modulation device (31, 32) as the at least one Kerr medium. Furthermore, a method of generating laser pulses by Kerr lens based mode locking is described, wherein a loss-modulation device (31, 32) is used for both of introducing a Kerr effect in the laser resonator (10) and modulating the power loss.
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公开(公告)号：EP3045181B1
公开(公告)日：2018-11-14
申请号：EP15151594.7
申请日：2015-01-19
发明人： Sutter, Gerd , Fux, Robert , Volz, Asisa , Song, Fei , Becker, Stephan , Eickmann, Markus
IPC分类号： C07K14/005 , A61K39/12
CPC分类号： A61K39/12 , A61K2039/53 , C07K14/005 , C12N2770/20022 , C12N2770/20034 , C12N2799/023
摘要： The present invention relates to the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) N nucleocapsid protein and/or an immunogenic fragment thereof, or a nucleic acid molecule encoding the MERS-CoV N nucleocapsid protein and/or the immunogenic fragment thereof, for use as a vaccine. The present invention further relates to an immunogenic composition comprising the MERS-CoV N nucleocapsid protein and/or an immunogenic fragment thereof, or a nucleic acid molecule encoding the MERS-CoV N nucleocapsid protein and/or the immunogenic fragment thereof. Furthermore, the present invention relates to a vector comprising a nucleic acid molecule encoding the MERS-CoV N nucleocapsid protein and/or an immunogenic fragment thereof, for use as a vaccine as well as a method of inducing a protective immune response against MERS-CoV.
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99.发明授权HYDROGENATION PROCESS USING ORDERED COBALT-ALUMINUM AND IRON-ALUMINUM INTERMETALLIC COMPOUNDS AS HYDROGENATION CATALYSTS 有权有序钴铝铁和铝 - 金属间化合物作氢化催化剂的加氢工艺
公开(公告)号：EP2419232B1
公开(公告)日：2018-02-28
申请号：EP10709558.0
申请日：2010-03-22
申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. , Ludwig-Maximilians-Universität München , Forschungszentrum Jülich GmbH
发明人： ARMBRÜSTER, Marc , KOVNIR, Kirill , GRIN, Juri , SCHLÖGL, Robert , GILLE, Peter , HEGGEN, Marc , FEUERBACHER, Michael
CPC分类号： C10G45/32 , B01J23/745 , B01J23/75 , B01J35/002 , B22F7/08 , B22F2998/00 , C07C7/167 , C10G2400/20 , C22C1/0491 , C22C21/00 , C30B11/00 , C30B15/00 , C30B17/00 , C30B29/52 , Y02P20/52 , C07C11/04 , B22F5/106
摘要： The present invention relates to a process for the hydrogenation, in particular the selective hydrogenation of unsaturated hydrocarbon compounds, such as the selective hydrogenation of acetylene to ethylene, using a hydrogenation catalyst comprising an ordered intermetallic compound, namely an ordered cobalt-aluminum or iron-aluminum intermetallic compound. According to another aspect, the present invention relates to a catalyst comprising a support and at least one specific ordered cobalt-aluminum and/or iron-aluminum intermetallic compound supported thereon, as well as to the use of specific ordered intermetallic cobalt-aluminum and iron-aluminum intermetallic compounds as catalysts. The ordered cobalt-aluminum and iron-aluminum intermetallic compounds proved to be highly selective and long-term stable catalysts, e.g. in the selective hydrogenation of acetylene to ethylene in a large excess of ethylene.
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100.发明公开
公开(公告)号：EP3271377A1
公开(公告)日：2018-01-24
申请号：EP16709392.1
申请日：2016-03-10
申请人： Ludwig-Maximilians-Universität München , Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
发明人： WILLEM, Michael , HAASS, Christian
IPC分类号： C07K14/435
CPC分类号： C07K14/4711 , A61K38/00 , G01N33/6896 , G01N2333/4709 , G01N2800/2821
摘要： The present invention relates to a peptide or collection of peptides derived from amyloid precursor protein (APP). The present invention also relates to uses of such peptide or collection of peptides, in particular as a diagnostic marker and/or as a drug target.
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