-
公开(公告)号：EP2374889A3
公开(公告)日：2012-02-22
申请号：EP10011713.4
申请日：1999-12-07
发明人： Ruelle, J. , Verlant, V.
CPC分类号： C07K16/1217 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K14/22
摘要： The invention provides BASB041, 43, 44 and 48 polypeptides and polynucleotides encoding BASB041, 43, 44 and 48 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
-
92.发明公开Method for identifying whether a patient will be responder or not to immunotherapy based on the differential expression of the IL7R gene 审中-公开一种用于响应或患者的无应答的识别方法免疫疗法基于所述基因IL7R的差异表达
公开(公告)号：EP2390361A1
公开(公告)日：2011-11-30
申请号：EP11163271.7
申请日：2007-05-31
发明人： Brichard, Vincent , Clark, James, Scott , Coche, Thierry , Gaulis, Swann, Romain, Jean-Thomas , Gruselle, Olivier , Lehmann, Frederic , Louahed, Jamila
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/158
摘要： The present invention relates to gene expression profiles, microarrays comprising nucleic acid sequences representing gene expression profiles and new diagnostic kits and methods. The invention further relates to treatment of specific populations of, for example, cancer patients, as characterised by their gene expression profile, suffering from Mage expressing tumours.
摘要翻译： 本发明涉及基因表达图谱，微阵列包括表示基因的表达谱和新的诊断试剂盒和方法的核酸序列。 本发明进一步涉及治疗的特定人群，例如，癌症患者，通过它们的基因表达谱所表征，从法师表达肿瘤的痛苦。
-
公开(公告)号：EP2301955A3
公开(公告)日：2011-11-16
申请号：EP10188215.7
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
-
公开(公告)号：EP2208999A3
公开(公告)日：2011-09-21
申请号：EP10160317.3
申请日：2005-09-05
IPC分类号： G01N33/569 , C12N1/22
CPC分类号： G01N33/56911 , G01N2333/22 , G01N2469/20
摘要： The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of scrum antibodies against meningococcus. In order to determine whether a subject or a population is seropositive against invasive meningococcus the SBA test should ideally be both sensitive and specific. The inventors have found the standard N. meningitidis serotype A and W SBAs can be significantly improved in this regard.
-
95.发明公开BASB006 polynucleotide(s) and polypeptides from Neisseria meningitis 审中-公开Basb006多核苷酸（n）和Polypeptiden aus奈瑟氏球菌脑膜炎
公开(公告)号：EP2360260A1
公开(公告)日：2011-08-24
申请号：EP10011715.9
申请日：1999-04-20
发明人： Thonnard, Joelle
IPC分类号： C12N15/31 , C07K14/22 , C07K16/12 , A61K39/095 , A61K48/00 , C12N5/10 , C12Q1/68 , G01N33/53 , A61P31/04
CPC分类号： C07K16/1217 , A61K38/00 , A61K39/00 , C07K14/22 , C12Q1/689 , G01N33/56911 , G01N2800/52
摘要： The invention provides BASB006 polypeptides and polynucleotides encoding BASB006 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
摘要翻译： 本发明提供BASB006多肽和编码BASB006多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了诊断，预防和治疗用途。
-
公开(公告)号：EP2305296A1
公开(公告)日：2011-04-06
申请号：EP10011107.9
申请日：2005-09-20
IPC分类号： A61K39/085 , A61K39/116 , A61P31/04 , C07K16/12
CPC分类号： A61K39/085 , A61K2039/505 , C07K16/1271
摘要： The present application relates to immunogenic compositions comprising a mixture of staphylococcal antigens which combines antigen having different functions, for instance, combinations including a staphylococcal extracellular component binding protein and a staphylococcal transporter protein or a staphylococcal extracellular component binding protein and a staphylococcal regulator of virulence or toxin or a staphylococcal transporter protein and a staphylococcal regulator of virulence or toxin. Vaccines, methods of treatment, uses of and processes to make a staphylococcal vaccine are also described.
-
97.发明公开Immunogenic composition for use in vaccination against staphylococcei 有权Antikörper-Zusammensetzung zur Verwendung zur Impfung gegen Staphylokokken
公开(公告)号：EP2305295A1
公开(公告)日：2011-04-06
申请号：EP10010739.0
申请日：2005-09-20
IPC分类号： A61K39/085 , A61K39/116 , A61P31/04 , C07K16/12
CPC分类号： A61K39/085 , A61K2039/505 , C07K16/1271
摘要： The present application relates to immunogenic compositions comprising a mixture of staphylococcal antigens which combines antigen having different functions, for instance, combinations including a staphylococcal extracellular component binding protein and a staphylococcal transporter protein or a staphylococcal extracellular component binding protein and a staphylococcal regulator of virulence or toxin or a staphylococcal transporter protein and a staphylococcal regulator of virulence or toxin. Vaccines, methods of treatment, uses of and processes to make a staphylococcal vaccine are also described.
摘要翻译： 本申请涉及包含具有不同功能的抗原的葡萄球菌抗原的混合物的免疫原性组合物，例如包括葡萄球菌细胞外组分结合蛋白和葡萄球菌转运蛋白或葡萄球菌细胞外组分结合蛋白的组合和毒力的葡萄球菌调节剂或 毒素或葡萄球菌转运蛋白和毒素或毒素的葡萄球菌调节剂。 还描述了疫苗，治疗方法，葡萄球菌疫苗的使用和方法。
-
公开(公告)号：EP2301955A2
公开(公告)日：2011-03-30
申请号：EP10188215.7
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
-
公开(公告)号：EP2281830A2
公开(公告)日：2011-02-09
申请号：EP10188214.0
申请日：2006-03-01
CPC分类号： A61K39/25 , A61K39/00 , A61K39/12 , A61K2039/5252 , A61K2039/5254 , A61K2039/55555 , A61K2039/55572 , A61K2039/55577 , C07K14/005 , C12N2710/16722 , C12N2710/16734
摘要： Use of an immunogenic composition comprising VZV gE, or immunogenic fragment thereof, and a TH-1 adjuvant in the preparation of a medicament for the prevention or amelioration of shingles and/or post herpetic neuralgia. Compositions comprising a truncated VZV gE antigen and an adjuvant containing QS21, cholesterol and 3D MPL arc also claimed.
-
公开(公告)号：EP1147190B1
公开(公告)日：2010-07-14
申请号：EP00905800.9
申请日：2000-01-28
发明人： CHEEVER, Martin, A. , GHEYSEN, Dirk
CPC分类号： C07K14/71 , A61K35/00 , A61K35/12 , A61K38/00 , C07K2319/02 , C07K2319/21 , C07K2319/30 , C07K2319/32 , C07K2319/43 , C07K2319/73 , C07K2319/75 , C12N15/62
-
-
-
-
-
-
-
-
-
搜索结果
315 条记录 (耗时 0.042 秒)
