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公开(公告)号:EP4090327A1
公开(公告)日:2022-11-23
申请号:EP21700866.3
申请日:2021-01-14
申请人: Institut National de la Santé et de la Recherche Médicale (INSERM) , Ecole Normale Supérieure de Lyon , UNIVERSITE CLAUDE BERNARD - LYON 1 , Centre national de la recherche scientifique , ENYO Pharma
发明人: DARTEIL, Raphaël , LUCIFORA, Julie , DURANTEL, David , RAMIERE, Christophe , LACOMBE, Benoît , LOTTEAU, Vincent , ANDRE, Patrice
IPC分类号: A61K31/167 , A61K31/397 , A61K31/4045 , A61K31/4162 , A61K31/42 , A61K31/423 , A61K31/426 , A61K31/439 , A61K31/4439 , A61K31/4545 , A61K31/496 , A61K31/513 , A61K31/55 , A61K31/575 , A61K31/675 , A61K31/7056 , A61K31/7072 , A61K31/708 , A61K31/7088 , A61K38/21 , A61P31/14
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公开(公告)号:EP3948407A1
公开(公告)日:2022-02-09
申请号:EP20714657.2
申请日:2020-04-03
申请人: Centre national de la recherche scientifique , Université Claude Bernard Lyon 1 , SORBONNE UNIVERSITE , Ecole Normale Supérieure de Paris , Université de Paris
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公开(公告)号:EP3839484A1
公开(公告)日:2021-06-23
申请号:EP19306658.6
申请日:2019-12-17
申请人: Centre National de la Recherche Scientifique , Ecole Normale Supérieure de Paris , SORBONNE UNIVERSITE
发明人: CHOUKET, Raja , CROQUETTE Vincent , ESPAGNE, Agathe , JULLIEN, Ludovic , LEMARCHAND Annie , LE SAUX Thomas , PELISSIER-TANON, Agnés , ZHANG, Ruikang
IPC分类号: G01N21/64
摘要: A method for detecting a reversibly photoswitchable chemical species in a sample, comprising the steps of:
a) illuminating the sample (S) with light suitable to be absorbed by the chemical species triggering a reaction affecting an optical property of the chemical species, said first light being periodically-modulated at a fundamental modulation frequency;
b) measuring the evolution of the optical property;
c) extracting at least one of an in-phase component at a frequency which is an even multiple of the fundamental modulation frequency; and a quadrature component at a frequency which is an odd multiple of the fundamental modulation frequency of a signal representing said evolution; and
d) using the extracted component or components for detecting the chemical species.
An apparatus for carrying out the method.-
公开(公告)号:EP3809191A1
公开(公告)日:2021-04-21
申请号:EP19290104.9
申请日:2019-10-17
申请人: Université Claude Bernard Lyon 1 , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- , Ecole Normale Supérieure de Lyon
摘要: The invention concerns an optical structure with non-linear optical properties comprising at least one stack comprising a central filter (1) and two optical sandwiching elements (2,3) between which said central filter (1) is interposed, wherein said central filter (1) is in a sol-gel matrix material, said material being doped with at least one optical limiting doping agent, the central filter (1) and the two optical elements (2,3) on either side thereof being assembled by bonding layers (4a, 4b) of a material based on the same sol-gel matrix as that of the central filter, the optical elements (2,3) on either side of the central filter (1) and the bonding layers (4a, 4b) each having a refractive index equal to that of the material of the central filter or only differing from this refractive index within a range of plus or minus 0.05, preferably within a range of plus or minus 0.02.
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105.
公开(公告)号:EP3807295A1
公开(公告)日:2021-04-21
申请号:EP19729797.1
申请日:2019-06-17
申请人: College de France , Ecole Normale Supérieure , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , SORBONNE UNIVERSITE , Centre National de la Recherche Scientifique (CNRS)
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106.
公开(公告)号:EP3759687A1
公开(公告)日:2021-01-06
申请号:EP18708651.7
申请日:2018-02-28
发明人: HILD, François , LECLERC, Hugo , ROUX, Stéphane
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公开(公告)号:EP3679170A1
公开(公告)日:2020-07-15
申请号:EP17792179.8
申请日:2017-09-08
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108.
公开(公告)号:EP3678532A1
公开(公告)日:2020-07-15
申请号:EP18778371.7
申请日:2018-09-06
申请人: Centre National de la Recherche Scientifique , Ecole Normale Supérieure de Paris , Ecole Des Hautes Etudes En Sciences Sociales
IPC分类号: A61B5/00 , A61B5/16 , A61B5/0476 , G16H50/20
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公开(公告)号:EP3620840A1
公开(公告)日:2020-03-11
申请号:EP18306171.2
申请日:2018-09-05
申请人: Sorbonne Université , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , Ecole Normale Supérieure de Paris
IPC分类号: G02B21/14
摘要: Device for phase microscopy comprising:
• a spatial light modulator (31),
• a connecting means (33) adapted to fix the spatial light modulator onto a phase microscope (1), said phase microscope (1) comprising a light path comprising at least a sample area (5), a lighting device (3) for lighting said sample area and an imaging device (13) for capturing a phase image of said sample, said phase image being a 2D matrix of pixels, so that the spatial light modulator (31) is positioned in the light path in a conjugated plane of the sample area (5) and
• a command (35) of the spatial light modulator (31) connected to the imaging device (13) and adapted to measure the phase shift of a plurality of pixels of the phase image and to command the spatial light modulator (31) in order to substract the measured phase shifts.-
110.
公开(公告)号:EP3613121A1
公开(公告)日:2020-02-26
申请号:EP18713335.0
申请日:2018-03-12
申请人: PSA Automobiles SA , Centre National de la Recherche Scientifique , Ecole Normale Supérieure de Cachan
发明人: ROY, Francis , REVOL, Bertrand
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