摘要:
Devices, delivery systems and delivery techniques for an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices, delivery systems and delivery techniques relate particularly to, but are not limited to, a patent foramen ovale (PFO) occluder made from a polymer tube. Specifically, a petal-shaped occluder with a catch system is provided within a delivery sheath. In certain embodiments, the delivery system includes a first securement system for securing a first end of the occluder and a second securement system for securing a second end of the occluder to a delivery catheter and a delivery wire contained in the delivery system. The securement enable the deployment (and retrieval) of the device. The securement systems enable pushing and pulling of respective ends of the occluder to expand and contract the device by varying its axial length. In one aspect, the first securement system employs a threaded connection and the second securement system employs a suture connection. In another aspect, the first securement system employs a threaded connection and the second securement system employs a collet finger connection. The securement systems are detached when the device has been properly positioned. The securement systems can be manipulated by control systems provided in the control portion of the delivery system.
摘要:
The present invention provides a device for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO). The occluder includes two sides connected by a central tube. In some embodiments, the occluder is formed from filaments that are joined together to define a substantially cylindrical form with openings defining struts. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. The occluder further includes a catch system that maintains its deployed state in vivo. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system in engaged so that the occluder closes the aperture.
摘要:
An occluder for closing an opening in a circuit system can be transferred from a compact manifestation which extends along a longitudinal axis (7) into an expanded manifestation. The occluder has a first expansion unit and a second expansion unit which bear on in each case one side of the opening in the expanded manifestation. Furthermore, the occluder has a first coupling part (1) and a second coupling part (2) which can be brought into engagement with one another, with the result that they fix the occluder in its expanded manifestation. The first coupling part (1) has a region (12) which extends between the first and second expansion units in the expanded manifestation. According to the invention, this region (12) is configured such that it can expand along the longitudinal axis (7). It is preferably configured such that it can expand counter to a restoring force, that is to say resiliently or elastically. This occluder therefore permits automatic setting of the spacing between two expansion and/or closure units according to the structural conditions at the location of the opening to be closed.
摘要:
An adjustable occlusion device and a method of implanting the device in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed.
摘要:
In a placement system with a stretching element (18) and at least one holding wires (17), the stretching element (18) serves for interacting with a distal end (12) of an implant and the holding wire or wires (17) serve for interacting with a proximal end (13) of an implant, the implant being capable of being transformed from a primary form into a secondary form and vice versa by relative movement of the holding wires (17) in relation to the stretching element (18).
摘要:
In a method for sealing an incision in an interior body wall such as a gastrotomy opening in a stomach, a closure device (10) is positioned within the incision. The closure device includes a seal (12b) and an anchor (12a) coupled to the seal. The seal is positioned in sealing contact against a first surface surface of the body wall, and the anchor is positioned against the second surface of the body wall such that a portion of the closure device is positioned. The closure device seals the incision while healing takes place. Once the incision is significantly healed, the closure device bioerodes.