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公开(公告)号：EP3586423A1
公开(公告)日：2020-01-01
申请号：EP18707083.4
申请日：2018-02-05
申请人： PSA Automobiles SA , Centre National de la Recherche Scientifique , Ecole Normale Supérieure de Cachan
发明人： ROY, Francis , REVOL, Bertrand
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112.发明授权
公开(公告)号：EP2764415B1
公开(公告)日：2019-12-18
申请号：EP12769095.6
申请日：2012-10-04
IPC分类号： B64C1/06 , B64C1/00 , B64F5/10 , G06F17/50 , G05B19/4097
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113.发明公开
公开(公告)号：EP3506951A1
公开(公告)日：2019-07-10
申请号：EP17755452.4
申请日：2017-08-10
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公开(公告)号：EP3207417B1
公开(公告)日：2019-05-01
申请号：EP15781105.0
申请日：2015-10-15
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公开(公告)号：EP3453450A1
公开(公告)日：2019-03-13
申请号：EP17306170.6
申请日：2017-09-12
申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , Ecole Normale Supérieure de Paris , Ecole Supérieure de Physique et de Chimie Industrielles de la Ville de Paris , Université de Versailles Saint-Quentin-en-Yvelines , Instituto Superior Técnico
发明人： SERRE, Christian , PINTO, Moisès L.
摘要： The present invention relates, inter alia, to the use of porous crystalline solids constituted of a metal-organic framework (MOF) for the capture of polar volatile organic compounds (VOCs). In particular, the MOF of interest are material comprising an average pores sizes of 0.4 to 0.6 nm and an hydrophobic core formed by a metal oxide and/or hydroxide network connected by linkers, said linkers being selected from the group comprising (i) C 6 -C 24 aromatic polycarboxylate linkers, such as benzyl or naphtyl di-, tri- or tetracarboxylate, and (ii) C 6 -C 16 polycarboxylate aliphatic linkers; the linkers bearing or not apolar fluorinated groups, e.g. -(CF 2 ) n -CF 3 groups, n being a integer from 0 to 5, preferably 0 ou 3, and/or apolar C 1 -C 20 preferably C 1 -C 4 alkyl groups, e.g. -CH 3 or -CH 2 -CH 3 , grafted directly to the linkers and pointing within the pores of the MOF. The MOF solids used in the present invention can be used for the purification of air, for example for the capture of polar VOCs like acetic acid and aldehydes from indoor air in cars, museums and archives, much more efficiently than common adsorbents, particularly in presence of humidity. They can in particular be used for the preservation of cultural heritage.
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公开(公告)号：EP3425386A1
公开(公告)日：2019-01-09
申请号：EP17180388.5
申请日：2017-07-07
申请人： Université de Strasbourg , UNIVERSITE CLAUDE BERNARD - LYON 1 , Ecole Normale Supérieure de Lyon , Centre National de la Recherche Scientifique (CNRS)
摘要： The present invention relates to an apparatus and a method for separating and analyzing molecules, in particular proteins such as ADCs. To answer ADCs requirements, the apparatus and the method of the present invention are based on the direct connection between non-denaturing chromatography selected from hydrophobic interaction chromatography, size exclusion chromatography and ion exchange chromatography, size exclusion chromatography and non-denaturing mass spectrometry to answer ADCs requirements.
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公开(公告)号：EP3354659A3
公开(公告)日：2018-09-12
申请号：EP18156497.2
申请日：2014-07-30
申请人： URGO RECHERCHE INNOVATION ET DEVELOPPEMENT , Centre National de la Recherche Scientifique CNRS , Université Paris Diderot - Paris 7 , INSERM (Institut National de la Santé et de la Recherche Médicale) , Ecole Normale Supérieure
IPC分类号： C07K14/47 , C12N15/113 , A61K9/00 , A61K45/06 , A61L15/16 , A61K31/197 , A61K31/506 , A61K31/519
CPC分类号： A61K31/519 , A61K9/0014 , A61K31/197 , A61K31/506 , A61K45/06 , A61L15/16 , A61L2300/432 , C07K14/4702 , C12N15/113 , C12N2310/14
摘要： The present invention relates to a therapeutic compound comprising:
- an agent that inhibits the activity of at least one gene selected from the group consisting of MEOX2, SIX2 and homologues thereof having at least 50% identity with said genes
and/or
- an agent that enhances the activity of at least one gene selected from the group consisting of CREB5, E2F1, EGR2, HIC1, IRF7, JUN, MYC, SRF, STAT4, TCF4, FOXS1, GLI1, SOX9 and homologues thereof having at least 50% identity with said gene
for use in the treatment of wounds, preferably chronic wounds.-
公开(公告)号：EP3365667A1
公开(公告)日：2018-08-29
申请号：EP16785160.9
申请日：2016-10-21
申请人： Ecole Polytechnique , Centre National de la Recherche Scientifique , Sensome , Ecole Normale Supérieure de Cachan
发明人： BOZSAK, Franz , BARAKAT, Abdul , MESSINA, Pierluca , FRANCAIS, Olivier , CARREEL, Bruno , LE PIOUFLE, Bruno , COTTANCE, Myline
IPC分类号： G01N27/02 , G01N33/487 , G01N33/483
CPC分类号： A61B5/053 , A61B5/0031 , A61B5/0537 , A61B5/4851 , A61B5/6851 , A61B5/6852 , A61B5/686 , A61B5/6862 , A61B2562/0214 , C12Q1/04
摘要： The invention relates to a method for discriminating cells of a cellular structure, notably of a cellular tissue, comprising the steps consisting in determining (12) a frequency spectrum of the impedance of the cellular structure; defining (22) at least one model of the impedance of the cellular structure including a constant phase element (30); determining (44) the impedance of the constant phase element (30) which optimizes the correlation of each model of the impedance of the cellular structure with the spectrum; and deducing (66), from the impedance of the constant phase element (30) or from the impedances of the constant phase elements (30), an item of information on the cells of the cellular structure. The invention also relates to a system for implementing the method for discriminating cells of a cellular structure.
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119.发明公开DISPOSITIF MEDICAL MUNI DE CAPTEURS A IMPEDANCE VARIABLE 审中-公开DISPOSITIF MEDICAL MUNI DE CAPTEURS阻抗变量
公开(公告)号：EP3200675A1
公开(公告)日：2017-08-09
申请号：EP15771665.5
申请日：2015-10-02
申请人： Centre National de la Recherche Scientifique , Ecole Polytechnique , Ecole Normale Supérieure de Cachan
发明人： BARAKAT, Abdul , BOZSAK, Franz , BONNASSIEUX, Yvan Eric , LE PIOUFLE, Bruno , FRANCAIS, Olivier , CARREEL, Bruno
IPC分类号： A61B5/00
CPC分类号： A61B5/6862 , A61B5/0031 , A61B5/4851 , A61B5/7225 , A61B2560/0219 , A61F2/82
摘要： The invention relates to a medical device (12) comprising an electrical measurement circuit (16), in which are connected at least two sensors (22) with variable impedance according to a physical magnitude detected, an electric energy source (18) for powering the electric measurement circuit (16), an antenna (18) for emitting an electromagnetic field in accordance with the impedance of the electrical measurement circuit (16), each of the sensors (22) being associated with a switch (24) so as to short-circuit the sensor (22) in said measurement circuit (16), the medical device (12) also including a system (26) for controlling the switches (24) in order consecutively to control the opening or the closing of the switches (24), according to predetermined configurations. In particular, the medical device (12) can be used on the human body or implanted in the human body.
摘要翻译： 本发明涉及包括电测量电路（16）的医疗设备（12），其中根据检测到的物理量值连接至少两个具有可变阻抗的传感器（22），电能源（18） ，电测量电路（16），根据电测量电路（16）的阻抗发射电磁场的天线（18），每个传感器（22）与开关（24）相关联以便短路 - 在所述测量电路（16）中电路传感器（22），医疗设备（12）还包括用于依次控制开关（24）以控制开关（24）的断开或闭合的系统 ），根据预定的配置。 特别地，医疗装置（12）可以用于人体或植入人体。
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120.发明授权CYCLOALKANE OXIDATION CATALYSTS AND METHOD TO PRODUCE ALCOHOLS AND KETONES 有权CYCLOALKANOXIDATIONSKATALYSATOREN UND VERFAHREN ZUR HERSTELLUNG VON ALKOHOLEN UND KETONEN
公开(公告)号：EP2986585B1
公开(公告)日：2017-06-21
申请号：EP14718580
申请日：2014-04-17
发明人： DECAMPO FLORYAN , ZHOU WENJUAN
IPC分类号： C07C29/48 , C07C35/06 , C07C35/08 , C07C35/20 , C07C45/28 , C07C45/29 , C07C49/395 , C07C49/403 , C07C49/413
CPC分类号： C07C45/28 , C07C29/48 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C35/08 , C07C35/06 , C07C35/20 , C07C49/395 , C07C49/403 , C07C49/413
摘要： The present invention concerns a method of oxidizing a cycloalkane to form a product mixture containing a corresponding alcohol and ketone, said method comprising contacting a cycloalkane with an oxidant agent in the presence of catalytic effective amount of metal triflates or metal triflimidates catalysts.
摘要翻译： 本发明涉及氧化环烷烃以形成含有相应的醇和酮的产物混合物的方法，所述方法包括在催化有效量的金属三氟甲磺酸盐或金属三氟磷酸盐催化剂存在下，使环烷烃与氧化剂接触。
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