-
公开(公告)号：EP0413307A1
公开(公告)日：1991-02-20
申请号：EP90115575.4
申请日：1990-08-14
申请人： LION CORPORATION
发明人： Miyake, Hiroshi , Kurahashi, Midori , Toda, Haruhiko , Kitano, Kyozo , Mori, Takao, Room No. 405
摘要： A process for producing a saccharide fatty acid monoester comprises reacting an immobilized thermostable lipase on a mixture comprising:
(A) one or more of acyl donors selected from saturated and unsaturated fatty acids with 6 to 22 carbon atoms, lower alkyl esters of said fatty acids and glycerol esters of said fatty acids,
(B) one or more of saccharides selected from monosaccharides with 5 to 7 carbon atoms, disaccharides composed of hexose, sugar alcohols with 4 to 6 carbon atoms, ethers of monosaccharides with 5 to 7 carbon atoms and monohydric alcohols and ethers of disaccharides composed of hexose and monohydric alcohols, and
(C) one or more of alcohols selected from secondary alcohols and tertiary alcohols.摘要翻译： 生产糖脂肪酸单酯的方法包括使固定的热稳定脂肪酶在混合物上反应，所述混合物包含：（A）一种或多种选自具有6-22个碳原子的饱和和不饱和脂肪酸的酰基供体，所述脂肪酸的低级烷基酯 和（B）一种或多种选自具有5至7个碳原子的单糖，由己糖构成的二糖，具有4至6个碳原子的糖醇，具有5至7个碳原子的单糖的醚和 由己糖和一元醇组成的二元醇的一元醇和醚，以及（C）选自仲醇和叔醇的一种或多种醇。
-
142.发明公开Method for preparing a vaccine from Streptococcus mutans for dental caries and vaccinal compositions for dental caries used as nasal drops 失效一种用于变形链球菌的抗龋疫苗的制备和对以滴鼻剂形式龋疫苗组合物的过程。
公开(公告)号：EP0400569A2
公开(公告)日：1990-12-05
申请号：EP90110144.4
申请日：1990-05-29
CPC分类号： A61K9/0043 , A61K39/00 , C07K14/315 , Y02A50/472
摘要： A method for preparing a vaccine for dental caries comprises the step of culturing a variant which is obtained by integrating a protein antigen (PAc)-expressing gene into the chromosomal gene of a Streptococcus mutans GS-5 strain to obtain the protein antigen, the protein antigen being produced on the surface of cells of oral Streptococcus mutans or it being extracellularly produced by the microorganism and having a molecular weight ranging from about 170,000 to 220,000. Streptococcus mutans GS-5 (K-3), in which a protein antigen-expressing gene is integrated into the chromosomal gene thereof, has an ability of producing the protein antigen on the surface of the cells or extracellularly. A preventive vaccine composition for dental caries for nasal drops comprises the protein antigen thus produced by the strain: Streptcoccus mutans, the vaccine being intranasally administered. The method makes it possible to enhance the yield of PAc and to simplify processes for purifying PAc. The vaccine composition makes it possible to internally easily absorb the protein antigen, PAc, in high efficiency and it also makes it possible to effectively increase the antibody titer observed after the administration thereof. 1
摘要翻译： 一种制备疫苗用于龋齿的方法包括由INTEGRA婷蛋白质抗原（PAC） - 表达基因导入变异链球菌GS-5菌株的染色体基因，以获得蛋白质抗原，蛋白质获得的培养变体的所有的步骤 抗原被口服变形链球菌细胞表面上产生，或者它被细胞外由所述微生物产生和具有分子量为约17万至22万。 变形链球菌GS-5（K-3）中，其中的蛋白质抗原表达基因整合到染色体基因体，具有产生细胞或细胞外的表面上的蛋白质抗原的能力。 龋齿为滴鼻剂预防性疫苗组合物包含蛋白质抗原由应变如此产生：Streptcoccus变形链球菌，疫苗被鼻内施用。 该方法使得有可能提高PAC的收率和简化工艺用于纯化的PAC。 所述疫苗组合物能够在内部容易地吸收蛋白质抗原，PAC在高效率，因此使得有可能有效地增加其给药后的抗体效价观察。
-
公开(公告)号：EP0348976A3
公开(公告)日：1990-11-07
申请号：EP89111864.8
申请日：1989-06-29
申请人： LION CORPORATION
发明人： Nishida, Yuichi
CPC分类号： A61Q5/00 , A61K8/375 , A61K8/8152 , A61K47/32 , A61K2800/5428 , A61Q5/06
摘要： A liquid composition containing a crystalline compound dissolved in a solvent, which comprises at least one kind of amphoteric polymers containing a structural unit represented by the following formula [I]:
wherein R' is a hydrogen atom or a methyl group, R 2 is an alkyl group having a carbon number of 8 to 20 or a cycloalkyl group having a carbon number of 5 to 7, formulated in said composition. The liquid composition according to the present invention is excellent in a low-temperature stability, with turbidity of the solution or precipitation of the crystals being hardly observed even when stored at a low temperature over a long period.-
公开(公告)号：EP0233689B1
公开(公告)日：1990-07-11
申请号：EP87300244.8
申请日：1987-01-12
申请人： LION CORPORATION
发明人： Abe, Seiji , Nakamura, Masayoshi
CPC分类号： C11D3/222 , C11D3/1286
-
公开(公告)号：EP0376448A1
公开(公告)日：1990-07-04
申请号：EP89311296.1
申请日：1989-11-01
申请人： LION CORPORATION
发明人： Miyano, Masakazu , Ueno, Akira , Nakajyu, Isamu , Sato, Teiji
IPC分类号： A61L9/01
CPC分类号： A61L9/01
摘要： A deodorizer composition comprising:
(a) an activated charcoal, a silica gel, a clay mineral, or an aluminosilicate having the following composition, in terms of oxides, represented by the composition ratio of the three components:
Si0 2 : 5 to 80 mole%;
MO n/2 : 5 to 65 mole%;
Al 2 O 3 : 1 to 60 mole%
wherein M represents at least one metal selected from the group consisting of zinc, copper, silver, cobalt, nickel, iron, titanium, barium, tin and zirconium, and n represents a valence of metal; and
(b) at least one component selected from the group consisting of oxidizing agents, plant extracts, and germicides.摘要翻译： 一种除臭剂组合物，其包含：（a）以三种组分的组成比表示的具有以氧化物计的以下组成的活性炭，硅胶，粘土矿物或硅铝酸盐：SiO 2：5至80摩尔％ ; 1/5：65〜65摩尔％ Al 2 O 3：1〜60摩尔％，其中M表示选自锌，铜，银，钴，镍，铁，钛，钡，锡和锆中的至少一种金属，n表示金属的价数; 和（b）至少一种选自氧化剂，植物提取物和杀菌剂的组分。
-
公开(公告)号：EP0344708A3
公开(公告)日：1990-04-11
申请号：EP89109723.0
申请日：1989-05-30
申请人： LION CORPORATION
摘要： A composition for external application to skin comprises one effective component such as compounds obtained by oxidizing coenzyme A and compound R-SH to dehydrogenate and form S-S bonds. The composition is used as a composition for healing traumas or a cosmetic composition for external application to the skin which have a variety of effects such as activation of dermal cells, promotion of their metabolism and healing of traumas and which, upon applying to the skin, prevent aging of the skin and provide wrinkle-free, smooth, moist and young-looking skin. The composition may have a variety of preparation forms such as a cosmetic cream, a milky lotion, a toilet water, a beauty essence, a pack, an undermakeup, a foundation, a jelly and an ointment.
-
147.发明公开
公开(公告)号：EP0344708A2
公开(公告)日：1989-12-06
申请号：EP89109723.0
申请日：1989-05-30
申请人： LION CORPORATION
摘要： A composition for external application to skin comprises one effective component such as compounds obtained by oxidizing coenzyme A and compound R-SH to dehydrogenate and form S-S bonds. The composition is used as a composition for healing traumas or a cosmetic composition for external application to the skin which have a variety of effects such as activation of dermal cells, promotion of their metabolism and healing of traumas and which, upon applying to the skin, prevent aging of the skin and provide wrinkle-free, smooth, moist and young-looking skin. The composition may have a variety of preparation forms such as a cosmetic cream, a milky lotion, a toilet water, a beauty essence, a pack, an undermakeup, a foundation, a jelly and an ointment.
摘要翻译： 用于外用于皮肤的组合物包含一种有效成分，例如通过氧化辅酶A和化合物R-SH获得的化合物脱氢并形成S-S键。 该组合物用作治疗创伤的组合物或外用于皮肤的化妆品组合物，其具有各种效果，例如真皮细胞的活化，促进其代谢和创伤愈合，并且在施用于皮肤时， 防止皮肤老化，并提供无皱纹，光滑，潮湿和年轻的皮肤。 组合物可以具有各种制剂形式，例如化妆品霜，乳液，马桶水，美容精华，包装，脱皮剂，粉底，果冻和软膏。
-
公开(公告)号：EP0332175A3
公开(公告)日：1989-11-29
申请号：EP89104123.8
申请日：1989-03-08
申请人： LION CORPORATION
发明人： Takizawa, Masahiro , Matsui, Yumiko , Arai, Hiroto
IPC分类号： B01J13/02
CPC分类号： B01J13/206 , A61K8/11 , A61K8/676 , A61K8/8129 , A61K9/5026 , A61K2800/412 , A61Q5/00 , A61Q11/00 , A61Q19/00
摘要： A method of producing microcapsules comprising the steps of:
mixing (i) an aqueous dispersion containing a capsule having an wall membrane containing polyvinyl alcohol and an aqueous solution containing 8% to 50% by weight of an electrolyte or electrolytes and (ii) an aldehyde or aldehydes having a solubility in water at 20°C of not more than 10%; and
allowing the mixture to react under an acidic condition.-
公开(公告)号：EP0328697A1
公开(公告)日：1989-08-23
申请号：EP88102215.6
申请日：1988-02-15
申请人： LION CORPORATION
IPC分类号： C11D3/39
摘要： A bleaching composition comprises:
(A) hydrogen peroxide and/or a hydrogen peroxide addition compound such as a percarbonate; and
(B) at least one activator which is a nitrogen-containing heterocyclic compound in which a halogen atom is substituted for the hydrogen atom of the secondary amino group or a non-heterocyclic N-halo-hindered amine compound, the hydrolysis constant of the activator being within the range of 1 x 10⁻¹⁰ to 5 x 10⁻⁶ (at 25°C). Examples of the activator include 1-chloro-piperidine, 1-chloro-2-methyl-piperidine, 1-chloro-isonipecotic acid, 1-chloro- -hexamethyleneimine and 1-chloro-ε-caprolactam. The bleaching-detergent composition may also contain the components (A) and (B) together with a surfactant. These compositions exhibit an excellent effect concerning bleaching at low temperature, but hardly affect the colors of colored and patterned clothes.摘要翻译： 漂白组合物包含：（A）过氧化氢和/或过氧化氢加成化合物如过碳酸盐; 和（B）至少一种作为其中卤素原子取代仲氨基的氢原子的含氮杂环化合物或非杂环N-卤代 - 位阻胺化合物的活化剂，其水解常数 活化剂在1×10 -1 <0℃至5×10 -6的范围内（在25℃）。 活化剂的实例包括1-氯 - 哌啶，1-氯-2-甲基 - 哌啶，1-氯异丙酸，1-氯 - 六亚甲基亚胺和1-氯 - ε-己内酰胺。 漂白洗涤剂组合物还可以与表面活性剂一起含有组分（A）和（B）。 这些组合物在低温下表现出优异的效果，但几乎不影响着色和图案化的衣物的颜色。
-
公开(公告)号：EP0269351A3
公开(公告)日：1989-07-12
申请号：EP87310132.3
申请日：1987-11-17
申请人： LION CORPORATION
IPC分类号： C12P7/64
摘要： A method for producing a fat containing γ-linolenic acid comprising the steps of culturing a microorganism belonging to the genus Absidia , the genus Mortierella , the genus Mucor , the genus Rhizopus or the genus Syncephalastrum with a fatty acid or an ester thereof as the carbon source, and converting the fatty acid or the ester thereof to γ-linolenic acid.
-
-
-
-
-
-
-
-
-
搜索结果
285 条记录 (耗时 0.017 秒)
