公开(公告)号：EP1443036B1

公开(公告)日：2015-10-28

申请号：EP04002111.5

申请日：2004-01-31

申请人： NIPPON SHOKUBAI CO., LTD.

发明人： Morishita, Fumiaki ,  Tojo, Atsushi ,  Takinami, Takahiro ,  Sugiyama, Yutaka

IPC分类号： B01J29/40 ,  C07C213/04

CPC分类号： C07C213/04 ,  B01J29/405 ,  C07C215/10

摘要： A process for producing a high purity trialkanolamine excelling in hue and having an APHA of not more than 40, characterizing by including producing a mixed alkanolamine by the reaction of an alkylene oxide with ammonia; removing low-boiling substances from the mixed alkanolamine; removing high-boiling substances by subjecting the product deprived of the low-boiling substance to vacuum distillation, and redistilling the distillate obtained by the vacuum distillation.

公开(公告)号：EP2804477A4

公开(公告)日：2015-09-23

申请号：EP13738032

申请日：2013-01-17

申请人： DOW AGROSCIENCES LLC

发明人： LI RUOKANG ,  DIXIT RAVINDRA S ,  PATEL AVANI M ,  CHEN XIAOYUN ,  PELL RANDY J ,  PENDERGAST JOHN G

IPC分类号： A01N33/12 ,  C07C213/04 ,  C07C215/40 ,  C07C217/08

CPC分类号： C07C213/04 ,  C07C217/08 ,  C07C215/40

摘要： Processes for preparing N,N,N-trimethylethanolammonium hydroxide (choline hydroxide) and the choline hydroxide produced are described. These processes minimize the production of byproduct mono-ethoxylated and di-ethyoxylated choline in the product choline hydroxide. The processes generally include feeding ethylene oxide, trimethylamine, and water into a first reactor to create a first reactor product under temperature controlled conditions. The product of the first reactor is fed into a second reactor to form a second reactor product under uncontrolled, adiabatic, conditions. Finally, any unreacted trimethylamine in the second reactor product is removed to form a final product comprising choline hydroxide. Additional reactors can be used for the ethylene oxide and trimethylamine reaction.

公开(公告)号：EP1991198B1

公开(公告)日：2014-11-19

申请号：EP07703479.1

申请日：2007-02-13

申请人： Unilever PLC ,  Unilever N.V.

发明人： HARICHIAN, Bijan ,  ROSA, Jose, Guillermo

IPC分类号： A61K8/41 ,  A61Q19/00 ,  C07C213/04 ,  C07C217/28 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q19/10 ,  A61K8/02

CPC分类号： A61K8/416 ,  A61K8/0208 ,  A61Q1/02 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q19/007 ,  A61Q19/10 ,  C07C217/28

公开(公告)号：EP2797873A1

公开(公告)日：2014-11-05

申请号：EP11813373.5

申请日：2011-12-29

申请人： Taminco

发明人： MOONEN, Kristof ,  ULRICHTS, Dieter ,  SCHELDEMAN, Daan

IPC分类号： C07C213/04

CPC分类号： C07C213/10 ,  C07C213/04 ,  C07C215/40

摘要： A continuous process for the production of choline hydroxide includes reacting ethylene oxide, trimethylamine, and water in a reaction zone to form a reaction mixture and extracting heat from the reaction mixture. Subsequently, phase separation of the reaction mixture is induced to obtain a choline hydroxide phase and an organic liquid phase comprising trimethylamine. A choline hydroxide solution (e.g., at a concentration of about 40% to 50% by weight, based on total weight of the choline hydroxide solution) is obtained from the choline hydroxide phase.

公开(公告)号：EP2423180A1

公开(公告)日：2012-02-29

申请号：EP11008855.6

申请日：2002-12-04

申请人： Clariant Finance (BV) Limited

发明人： Gallotti, Manlio ,  De Moraes, Patricia Ramos Pereira ,  Cavalcante, Cássio Queiroz

IPC分类号： C07C211/63 ,  C07C213/04 ,  C07C213/08 ,  C11D1/835 ,  C07C217/50 ,  C11D1/62 ,  C11D3/43

CPC分类号： C11D1/835 ,  C11D1/62 ,  C11D1/72

摘要： A quaternary ammonium composition is claimed which essentially consists of
a) a cationic compound with general formula:

wherein R 1 is C 8 -C 22 -alkyl, C 8 -C 22 -alkenyl, C 8 -C 22 -alkylamidopropyl, C 8 -C 22 -alkenyl-amidopropyl, C 8 -C 22 -alkyl/alkenyl(poly)alkoxyalkyl, C 8 -C 22 -alkanoylethyl or C 8 -C 22 -alkenoylethyl, R 2 , R 3 and R 4 are C 1 -C 22 -alkyl, C 2 -C 22 -alkenyl or a group of the formula -A-(OA) n -OH, A is -C 2 H 4 - and/or -C 3 H 6 -, n is a number from 0 to 20 and X is an anion,
b) water and
c) a non-ionic solvent of the general formula R-O-(AO) n H, where R is hydrogen, alkyl or alkenyl containing 8 to 22 carbon atoms, or phenyl, A is C 2 H 4 and/or C 3 H 6 and n is a number from 0 to 20, which composition is characterized in that it contains less than 20 % by weight of water.

摘要翻译： 要求保护的季铵组合物，其主要由a）具有以下通式的阳离子化合物组成：其中R 1为C 8 -C 22 - 烷基，C 8 -C 22 - 烯基，C 8 -C 22 - 烷基酰氨基丙基，C 8 - C 22 - 烯基 - 酰氨基丙基，C 8 -C 22 - 烷基/烯基（多）烷氧基烷基，C 8 -C 22 - 烷酰基乙基或C 8 -C 22 - 烯丙基乙基，R 2，R 3和R 4是C 1 -C 22-烷基，C 2 -C 22 - 烯基或式-A-（OA）n -OH基团，A是-C 2 H 4 - 和/或-C 3 H 6 - ，n是 0至20，X为阴离子，b）水和c）通式为RO-（AO）n H的非离子溶剂，其中R为氢，含有8至22个碳原子的烷基或烯基，或苯基， A是C 2 H 4和/或C 3 H 6，n是0至20的数，该组成的特征在于其含有小于20重量％的水。

公开(公告)号：EP2348013A1

公开(公告)日：2011-07-27

申请号：EP10151583.1

申请日：2010-01-25

申请人： INKE, S.A.

发明人： Navarro Muñoz, Isabel ,  Huguet Clotet, Juan

IPC分类号： C07C213/04 ,  C07C217/70 ,  C07C233/43

CPC分类号： C07C213/04 ,  C07B2200/07 ,  C07C213/00 ,  C07C217/70 ,  C07C231/02 ,  C07C217/86 ,  C07C233/43

摘要： An improved method for the preparation of optically pure isomers of Formoterol is disclosed, particularly the (R,R)-isomer.
A method of preparation of substantially enantiomerically pure (R,R)-1-(4-Benzyloxy-3-nitro-phenyl)-2-[[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-amino]-ethanol to use in the production of (R,R)-Formoterol is also disclosed

摘要翻译： 公开了用于制备福莫特罗的光学纯异构体的改进方法，特别是（R，R） - 异构体。 制备基本上对映体纯的（R，R）-1-（4-苄氧基-3-硝基 - 苯基）-2 - [[2-（4-甲氧基 - 苯基）-1-甲基 - 乙基] - （ 也用于生产（R，R） - 孕甾醇的1-苯基 - 乙基） - 氨基] - 乙醇

公开(公告)号：EP2059494B1

公开(公告)日：2010-11-24

申请号：EP07801952.8

申请日：2007-08-29

申请人： Cognis IP Management GmbH

发明人： FRANZEN, Stefan ,  BÜTTGEN, Franz ,  MROZEK, Ingomar ,  GUTSCHE, Bernhard

IPC分类号： C07C41/03 ,  C07C43/11 ,  C07C67/26 ,  C07C213/04 ,  C08G65/26

CPC分类号： C07C41/02 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00788 ,  B01J2219/00822 ,  B01J2219/00824 ,  B01J2219/00828 ,  B01J2219/00831 ,  B01J2219/00833 ,  B01J2219/00835 ,  B01J2219/0086 ,  B01J2219/00867 ,  B01J2219/00869 ,  B01J2219/00873 ,  B01J2219/00889 ,  C07C41/03 ,  C07C213/04 ,  C08G65/2696 ,  C11D1/44 ,  C11D1/72 ,  C11D1/74 ,  C07C43/11

摘要： The invention relates to a method for producing alkylene oxide addition products by reaction of compounds having a nucleophilic center with alkylene oxides in a reactor having a large inner surface. The invention is characterized in that the reaction is carried out exclusively in the liquid phase.

公开(公告)号：EP2199377A1

公开(公告)日：2010-06-23

申请号：EP09175175.0

申请日：2009-11-05

申请人： Infineum International Limited

发明人： Tack, Robert

IPC分类号： C10L1/222 ,  C10L1/2387 ,  C10L1/22 ,  C10L1/14 ,  C10L10/14 ,  C07C213/04 ,  C07C213/00

CPC分类号： C10L1/221 ,  C07C217/28 ,  C10L1/143 ,  C10L1/1658 ,  C10L1/1973 ,  C10L1/1981 ,  C10L1/2225 ,  C10L1/238 ,  C10L1/2383 ,  C10L10/14

摘要： A fuel oil composition comprising a major amount of a fuel oil and a minor amount of a compound being the product of the reaction between (i) a primary or secondary hydrocarbyl-substituted amine or a mixture thereof and (ii) a species containing two or more epoxy groups being: a glycidyl ether (a) or (b), a glycidyl amine (c), a glycidyl ester (d) or a poly-epoxy alkane (e).

摘要翻译： 一种燃料油组合物，其包含主要量的燃料油和少量的化合物，其为（i）伯或仲烃基取代的胺或其混合物之间的反应产物，和（ii）含有两个或 更多的环氧基是：缩水甘油醚（a）或（b），缩水甘油胺（c），缩水甘油酯（d）或聚环氧烷烃（e）。

公开(公告)号：EP2192107A1

公开(公告)日：2010-06-02

申请号：EP08833059.2

申请日：2008-09-18

申请人： Sanyo Chemical Industries, Ltd.

发明人： YAMASHITA, Seiji

IPC分类号： C07C217/08 ,  C07C213/04 ,  C11D1/44

CPC分类号： C11D1/44 ,  C07C217/08

摘要： An object of the present invention is to provide an aliphatic amine alkylene oxide adduct which has a satisfactory color when used as a detergent, has a sufficiently sharp molecular weight distribution, and is highly pure and less odorous. The present invention is an aliphatic amine alkylene oxide adduct formed by adding m pieces of (A 1 O) and n pieces of (A 2 O) [wherein A 1 O and A 2 O each independently represent an oxyethylene group and/or an oxypropylene group] to an ethylene oxide 2-mole adduct of a primary amine having a saturated or unsaturated hydrocarbon group having 4 to 24 carbon atoms, the aliphatic amine alkylene oxide adduct having a color which, as expressed by the Gardener color scale, satisfies the following expression (1) or (2):
In the case where 1 ≤ m+n ≤ 15 Gardner color scale ≤ 0.5 × m + n + 2 - 1.5
In the case where 15 Gardner color scale ≤ 6

摘要翻译： 本发明的一个目的是提供脂肪胺胺氧化烯加合物，其在用作洗涤剂时具有令人满意的颜色，具有足够尖锐的分子量分布，并且高纯度和较少臭味。 本发明是通过将m个（A1O）和n个（A2O）[其中A1O和A2O各自独立地表示氧化乙烯基团和/或氧化丙烯基团]添加到环氧乙烷2-环氧乙烷形成的脂族胺烯化氧加合物， （1）或（2）表示的具有碳原子数为4〜24的饱和或不饱和烃基的伯胺的伯胺加成物， ：在1≤m+n≤15加德纳色标≤0.5×m + n + 2-1.5的情况下在15

公开(公告)号：EP2177501A1

公开(公告)日：2010-04-21

申请号：EP09171245.5

申请日：2009-09-24

申请人： Sulzer Chemtech AG

发明人： Fässler, Peter

IPC分类号： C07C213/04 ,  C07C215/08 ,  C07C215/12 ,  B01J19/00

CPC分类号： C07C213/04 ,  B01J2219/00006 ,  C07C215/08 ,  C07C215/12

摘要： A method for the production of ethanol amines comprises the steps of adding ammonia, ethylene oxide and water to a reactor (10). In the reactor, the ethylene oxide is reacted to a reaction product comprising a monoethanolamine, a diethanolamine and a triethanolamine. An ammonia stripper (20) for stripping the ammonia from the reaction product is provided. The reaction product is further concentrated in an evaporator (30) by evaporating water. The concentrated reaction product (31) is fed to a distillation plant (40) for separating the triethanolamine from the monoethanolamine and diethanolamine. The ammonia stripped from the reaction product (11) is fed to an ammonia absorber (100) for recycling the ammonia to the reactor (10).

摘要翻译： 制备乙醇胺的方法包括将氨，环氧乙烷和水加入到反应器（10）中的步骤。 在反应器中，环氧乙烷与包含单乙醇胺，二乙醇胺和三乙醇胺的反应产物反应。 提供了用于从反应产物中提取氨的氨汽提器（20）。 通过蒸发水将反应产物进一步浓缩在蒸发器（30）中。 将浓缩的反应产物（31）加入到蒸馏装置（40）中，以从单乙醇胺和二乙醇胺中分离出三乙醇胺。 将从反应产物（11）中汽提的氨进料到氨吸收塔（100），以将氨再循环到反应器（10）。