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公开(公告)号:EP1365826A2
公开(公告)日:2003-12-03
申请号:EP02727870.4
申请日:2002-02-26
申请人: Optinose AS
IPC分类号: A61M15/00
CPC分类号: A61M15/08 , A61B5/085 , A61B5/097 , A61B5/415 , A61B5/4839 , A61M11/001 , A61M11/005 , A61M11/006 , A61M11/007 , A61M11/02 , A61M15/002 , A61M15/0021 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M2016/0021 , A61M2202/04 , A61M2202/064 , A61M2205/071 , A61M2205/073 , A61M2205/13 , A61M2210/0668 , A61M2230/43
摘要: A nasal delivery device for delivering a substance to a nasal cavity of a subject, including: a nosepiece (240) adapted for insertion into a nostril of a subject; and a flow path fluidly connected to the nosepiece (240); wherein the nosepiece (240) is expandable and configured such as to expand on generation of a pressure in the flow path, thereby sealing with the nostril of the subject and providing for expansion of the nasal cavity of the subject.
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公开(公告)号:EP2817053B1
公开(公告)日:2018-05-30
申请号:EP13711301.5
申请日:2013-02-25
申请人: Optinose AS
发明人: DJUPESLAND, Per Gisle , DUDGEON, Kate , GORDON, Joseph , GUARRAIA, Mark , LECLERC, Michael , MAHMOUD, Ramy A
IPC分类号: A61M15/08
CPC分类号: A61M15/08 , A61M15/0021 , A61M2202/04 , A61M2202/064 , A61M2205/586 , A61M2210/0618 , A61M2210/0625
摘要: A nasal delivery device comprising: a housing (15); a nosepiece (17) for fitting to a nasal cavity of a subject; a mouthpiece (19) through which the subject in use exhales; and a substance supply unit (21) including an actuation member (23) which extends from one end of the housing and is manually actuated to deliver substance to the nasal cavity of the subject; wherein the housing includes a grip section (27) which is disposed at the one end of the housing from which the actuation member extends, said grip section comprising a first, distal part (28) including at least one projecting grip element (29) by which the subject grips the housing in actuating the actuation member, and a second, proximal part (31) providing a recess (33) in which fingers of the subject are located, said recess promoting proper orientation of the delivery device in a hand of the subject.
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公开(公告)号:EP3124067A3
公开(公告)日:2017-05-24
申请号:EP16180246.7
申请日:2000-03-03
申请人: Optinose AS
IPC分类号: A61M15/00 , A61M15/08 , A61M11/02 , A61M16/00 , A61M11/06 , A61M3/02 , A61M16/08 , A61M16/10
CPC分类号: A61M3/0233 , A61M3/0279 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0045 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/0866 , A61M16/1055 , A61M16/1065 , A61M2202/0468 , A61M2202/064 , A61M2205/43 , A61M2205/59 , A61M2206/10 , A61M2206/14 , A61M2210/0618 , A61M2210/0625
摘要: A nasal delivery device for delivering a substance to the nasal airway of a subject, comprising a delivery unit for delivering a gas flow and substance to one of the nostrils of the subject; wherein the delivery unit comprises a nosepiece which includes an outlet through which the gas flow and substance is in use delivered to the one nostril and a sealing member for providing a fluid tight seal between the outlet and the one nostril; wherein, during closure of the oropharyngeal velum of the subject, the delivery unit is configured to deliver the gas flow at a driving pressure to flow around the posterior margin of the nasal septum and out of the other nostril of the subject.
摘要翻译: 1.一种用于将物质递送至受试者的鼻气道的鼻递送装置,包括用于将气流和物质递送至受试者的鼻孔之一的递送单元; 其中所述输送单元包括喷嘴,所述喷嘴包括出口,所述气流和物质通过所述出口被输送至所述一个鼻孔,以及密封构件,用于在所述出口与所述一个鼻孔之间提供流体密封; 其中,在所述对象的口咽膜关闭期间,所述输送单元被配置为以驱动压力输送所述气流以围绕所述鼻中隔的后缘流动并流出所述对象的另一鼻孔。
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公开(公告)号:EP3124067A2
公开(公告)日:2017-02-01
申请号:EP16180246.7
申请日:2000-03-03
申请人: Optinose AS
CPC分类号: A61M3/0233 , A61M3/0279 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0045 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/0866 , A61M16/1055 , A61M16/1065 , A61M2202/0468 , A61M2202/064 , A61M2205/43 , A61M2205/59 , A61M2206/10 , A61M2206/14 , A61M2210/0618 , A61M2210/0625
摘要: A nasal delivery device for delivering a substance to the nasal airway of a subject, comprising a delivery unit for delivering a gas flow and substance to one of the nostrils of the subject; wherein the delivery unit comprises a nosepiece which includes an outlet through which the gas flow and substance is in use delivered to the one nostril and a sealing member for providing a fluid tight seal between the outlet and the one nostril; wherein, during closure of the oropharyngeal velum of the subject, the delivery unit is configured to deliver the gas flow at a driving pressure to flow around the posterior margin of the nasal septum and out of the other nostril of the subject.
摘要翻译: 一种用于将物质输送到对象的鼻气道的鼻输送装置,包括用于将气流和物质输送到受试者的鼻孔之一的输送单元; 其中所述输送单元包括喷嘴,所述喷嘴包括出口,所述气体流和物质在其中被输送到所述一个鼻孔;以及密封构件,用于在所述出口和所述一个鼻孔之间提供流体密封; 其中,在所述对象的口咽膜闭合期间,所述输送单元构造成以驱动压力输送所述气流以围绕所述鼻中隔的后缘流出并且离开所述受试者的另一个鼻孔。
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公开(公告)号:EP2332603B1
公开(公告)日:2013-08-14
申请号:EP10011952.8
申请日:2000-03-03
申请人: Optinose AS
CPC分类号: A61M3/0233 , A61M3/0279 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0045 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/0866 , A61M16/1055 , A61M16/1065 , A61M2202/0468 , A61M2202/064 , A61M2205/43 , A61M2205/59 , A61M2206/10 , A61M2206/14 , A61M2210/0618 , A61M2210/0625
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公开(公告)号:EP2460554A3
公开(公告)日:2013-01-23
申请号:EP12001127.5
申请日:2007-11-28
申请人: Optinose AS
发明人: Djupesland, Per, Gisle, Dr. , Sheldrake, Colin, David, Dr. , Smith, Simon , Striebig, Rachel , Pidgeon, Andy , St. Quintin, Tom
CPC分类号: A61M15/08 , A61M15/0018 , A61M15/0021 , A61M15/0026 , A61M15/0028 , A61M15/0035 , A61M15/0041 , A61M15/0043 , A61M15/0081 , A61M15/0098 , A61M16/1045 , A61M2202/064 , A61M2205/0222 , A61M2210/0618 , A61M2210/0625
摘要: A nasal delivery device for delivering particulate substance to the nasal airway of a subject, the delivery device comprising: a mouthpiece unit (209) which includes a mouthpiece (247) through which the subject in use exhales; a nosepiece unit (205) which includes a nosepiece (241) for fitting to a nostril of the subject; a substance-supply unit (211) which is configured to receive a container (C) containing particulate substance, the container (C) comprising a main body part (215) and first and second bearing support parts (217, 217) at the respective ends of the body part (215), and operable to provide a metered amount of substance in fluid communication with the mouthpiece and nosepiece units (209, 205), such that an exhalation air flow delivered through the substance-supply unit (211) entrains the substance; and a housing (203) which supports the mouthpiece unit (209), the nosepiece unit (205) and the substance-supply unit (211); wherein the substance-supply unit (211) includes a container-receiving member (251) which is movably disposed to the housing (203) between an open position for enabling loading of a container (C) thereinto and a closed position in which the container (C) is contained within the housing (203), and the container-receiving member (251) includes a cavity (253) which defines an air flow channel between the mouthpiece and nosepiece units (209, 205), such that an air flow is delivered therethrough on exhalation by the subject through the mouthpiece (247), and a support section for supporting the container (C) in the cavity (253) which includes first and second container supports (255, 255) for rotatably supporting the respective support parts (217, 217) of the container (C).
摘要翻译: 一种用于将颗粒物质输送到被检体的鼻气道的鼻输送装置,所述输送装置包括:口部单元(109),其包括接口(147),所述受试者在使用中呼气; 鼻梁单元(105),其包括用于装配到被检体的鼻孔的鼻梁(141) 以及物质供给单元(111),其构造成容纳含有颗粒物质的容器(C),并且可操作地提供计量的与所述接口管和鼻梁单元(109,105)流体连通的物质,使得呼气 通过物质供应单元(111)传送的空气流携带物质; 其中所述容器(C)包括第一和第二部分(115,117),所述第一部分和第二部分共同限定了封闭的腔室(119),并且可以在容器(C)关闭的第一闭合构型和第二打开构型之间移动 所述容器(C)打开,所述物质供应单元(111)可操作以将所述容器(C)的第一和第二部分(115,117)移动到所述打开构型。
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公开(公告)号:EP1180378B1
公开(公告)日:2010-11-10
申请号:EP01124194.0
申请日:2000-03-03
申请人: Optinose AS
CPC分类号: A61M3/0233 , A61M3/0279 , A61M15/0018 , A61M15/002 , A61M15/0021 , A61M15/0028 , A61M15/0045 , A61M15/0065 , A61M15/009 , A61M15/0091 , A61M15/0098 , A61M15/08 , A61M16/0866 , A61M16/1055 , A61M16/1065 , A61M2202/0468 , A61M2202/064 , A61M2205/43 , A61M2205/59 , A61M2206/10 , A61M2206/14 , A61M2210/0618 , A61M2210/0625
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公开(公告)号:EP1988953A1
公开(公告)日:2008-11-12
申请号:EP07705192.8
申请日:2007-02-14
申请人: Optinose AS
CPC分类号: A61M11/08 , A61M15/0065 , A61M15/0091 , A61M15/0095 , A61M15/0098 , A61M15/08 , A61M2016/0021 , A61M2016/0042 , A61M2202/04 , A61M2202/064 , A61M2205/276 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/75
摘要: A delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: at least one nosepiece unit (21) for insertion into one nasal cavity of a subject and comprising a nosepiece (25) for fitting to the respective nostril of the subject; and at least one delivery unit (23) which is operative to deliver a substance through the at least one nosepiece unit into the one nasal cavity of the subject, wherein the at least one delivery unit includes a substance supply unit (27) for delivering a substance and an actuation unit (29) which is operable to actuate the substance supply unit, either automatically or manually, in response to nasal exhalation or at least attempted nasal exhalation by the subject.
摘要翻译: 1。一种用于将物质递送至受试者的鼻气道的递送装置和方法,递送装置包括:至少一个用于插入受试者的一个鼻腔中的喷嘴单元(21),该喷嘴单元包括喷嘴(25) 主题各自的鼻孔; 和至少一个输送单元(23),所述输送单元(23)用于通过所述至少一个喷嘴单元将物质输送到所述对象的所述一个鼻腔中,其中所述至少一个输送单元包括物质供应单元(27),所述物质供应单元 物质和致动单元(29),所述致动单元(29)可响应于鼻呼气或至少尝试受试者的鼻呼气而自动地或手动地致动物质供应单元。
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