公开(公告)号：EP2253344A2

公开(公告)日：2010-11-24

申请号：EP10075380.5

申请日：2003-04-02

申请人： Baxter International Inc. ,  Baxter Healthcare S.A.

发明人： Han, James ,  Hartranft, Tomas ,  Kelly, tHOMAS ,  Lasso, Angel

IPC分类号： A61M1/36 ,  A61B5/00

CPC分类号： A61M1/3669 ,  A61M1/30 ,  A61M1/3653 ,  A61M1/3656 ,  A61M1/3659 ,  A61M1/3661 ,  A61M2205/13 ,  Y10S439/909

摘要： Apparatuses, devices, systems and methods for detecting access disconnection during medical therapy are provided. The present invention includes an electric circuit coupled to, for example, a blood circuit used during dialysis therapy. The electric circuit can be adapted to inject an electrical signal into the blood circuit such that changes in an electrical valve in response to access disconnection, such as needle drop-out or catheter drop-out, can be effectively detected.

摘要翻译： 提供了用于在药物治疗期间检测进入断开的装置，装置，系统和方法。 本发明包括耦合到例如在透析治疗期间使用的血液回路的电路。 电路可以适于将电信号注入到血液回路中，使得能够有效地检测响应于诸如针脱出或导管脱出的入口断开的电气阀的变化。

公开(公告)号：EP2214852A1

公开(公告)日：2010-08-11

申请号：EP07830718.8

申请日：2007-10-23

申请人： Nippon Light Metal Company, Ltd. ,  Nikkeikin Aluminium Core Technology Company, Ltd.

发明人： TAMAKI, Yuichi ,  SANADA, Kazuto ,  NISHIYAMA, Toshimasa

IPC分类号： B22F3/14

CPC分类号： C22C29/005 ,  B22F2998/10 ,  B22F2999/00 ,  C22C32/00 ,  C22C1/10 ,  B22F3/1216 ,  B22F3/16 ,  B22F3/02 ,  B22F3/18 ,  B22F2003/248

摘要： A method of producing an aluminum matrix composite material is described that comprises the steps of: mixing an aluminum powder and a ceramic powder to prepare a mixed powder; providing a lower casing made of aluminum and formed in a hollow rectangular parallelepiped shape having an open top, and a closing member made of aluminum and formed in a shape adapted to hermetically close the open top of the lower casing; packing the mixed powder into the lower casing; closing the open top of the lower casing filled with the mixed powder, by the closing member, to prepare a pre-rolling assembly having the mixed powder hermetically sealed therein; preheating the pre-rolling assembly; and rolling the preheated assembly to obtain the aluminum matrix composite material, where the aluminum matrix composite material includes a pair of metal plates having the mixed powder therebetween.

公开(公告)号：EP2308526B1

公开(公告)日：2013-03-27

申请号：EP10075426.6

申请日：2003-10-15

申请人： Baxter International Inc. ,  Baxter Healthcare S.A.

发明人： Childers, Robert W. ,  Avoy, Richard ,  Booras, John ,  Grippo, Paul ,  Hopping, Andrew D. ,  Howard, David ,  Jerrell, Jeffrey W. ,  Lauman, Brian ,  Shang, Sherwin ,  Yang, Tahua ,  Yu, Alex

IPC分类号： A61M1/28 ,  A61M1/16

CPC分类号： A61M1/281 ,  A61M1/16 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M2205/122

摘要： A method for aligning a disposable cassette (150) within a peritoneal dialysis machine (100) comprising the steps of: loading the disposable cassette (150) within the peritoneal dialysis machine; actuating a pump head (36) toward the disposable cassette; contacting a pumping chamber (168,172,174) of the disposable cassette with the pump head; using the pump head to shift the disposable cassette if need be into proper operational alignment with the pump head; and inflating a bladder (182) to lock the properly aligned disposable cassette in place.

公开(公告)号：EP2538960A1

公开(公告)日：2013-01-02

申请号：EP11746932.0

申请日：2011-02-25

申请人： Stellenbosch University

发明人： SMITH, Johan ,  VAN ZYL, Johann, Martin ,  VAN DER BIJL, Pieter ,  HAWTREY, Arthur, Owen

IPC分类号： A61K38/16 ,  A61K31/683 ,  A61P11/00

CPC分类号： A61K31/683 ,  A61K9/0082 ,  A61K38/02 ,  A61K38/16

摘要： The disclosure describes a composition comprising a lipidaceous carrier and a peptide complex formed from poly-L-lysine or a salt thereof; and either poly-L-glutamic acid or poly-L-aspartic acid, or a salt thereof. The composition can be used to prevent or treat a disease related to pulmonary surfactant dysfunction, such as hyaline membrane disease (HMD), respiratory distress syndrome (RDS), hydrocarbon poisoning, near-drowning, HIV/AIDS-related lung diseases, adult respiratory distress syndrome (ARDS), asthma, tuberculosis (TB) or severe acute respiratory syndrome (SARS). Alternatively, the composition can be used to increase the permeability of a pharmaceutical compound or composition across a membrane of a subject. The poly-L-lysine or salt thereof is longer than the poly-L-glutamic acid or poly-L-aspartic acid so that the complex that forms has a charge-neutralised region and a positively-charged region. The charge-neutralised region of the peptide complex interacts with the lipidaceous carrier, while the positively-charged region interacts with an aqueous and/or polar environment.

公开(公告)号：EP2536806A2

公开(公告)日：2012-12-26

申请号：EP11710003.2

申请日：2011-02-15

申请人： Mexichem Amanco Holding S.A. de C.V.

发明人： LOW, Robert, E.

IPC分类号： C09K3/30 ,  C09K5/04 ,  A23L1/00 ,  C08J9/14 ,  C11D7/50

CPC分类号： C09K5/045 ,  C08J9/146 ,  C09K3/30 ,  F25B39/02 ,  F25B45/00 ,  Y10T29/49716

摘要： The invention provides a heat transfer composition comprising trans-1, 3,3,3-tetrafluoropropene (R-1234ze(E)), fluoroethane (R-161) and a third component selected from difluoromethane (R-32) and/or 1, 1 -difluoroethane (R-152a).

摘要翻译： 本发明提供了包含反-1,3,3,3-四氟丙烯（R-1234ze（E）），氟乙烷（R-1​​61）和选自二氟甲烷（R-32）和/或1的第三组分的传热组合物 ，1-二氟乙烷（R-1​​52a）。

公开(公告)号：EP2536802A2

公开(公告)日：2012-12-26

申请号：EP11709162.9

申请日：2011-02-14

申请人： Mexichem Amanco Holding S.A. de C.V.

发明人： LOW, Robert, E.

IPC分类号： C09K3/30 ,  C09K5/04 ,  A23L1/00 ,  C08J9/14 ,  C11D7/50

CPC分类号： B01F17/0035 ,  B01D11/04 ,  B23P6/00 ,  C08J9/146 ,  C08J2203/202 ,  C09K3/00 ,  C09K3/30 ,  C09K5/045 ,  C09K5/048 ,  C09K2205/126 ,  C09K2205/22 ,  C09K2205/40 ,  C09K2205/43 ,  C11D7/5018 ,  C11D7/505 ,  G06Q30/018 ,  Y10T29/49716

摘要： The invention provides a heat transfer composition consisting essentially of from about 82 to about 88 % by weight of
trans -1,3,3,3-tetrafluoropropene (R-1234ze(E)) and from about 12 to about 18 % by weight of 1,1-difluoroethane (R-152a). The invention also provides a heat transfer composition comprising from about 5 to about 85 % by weight R- 1234ze(E), from about 2 to about 20 % by weight R-152a, and from about 5 to about 60 by weight 1,1,1,2-tetrafluoroethane (R-134a).

摘要翻译： 本发明提供一种传热组合物，其基本上由约82至约88重量％的反式-1,3,3,3-四氟丙烯（R-1234ze（E））和约12至约18重量％的 1,1-二氟乙烷（R-1​​52a）。 本发明还提供了一种传热组合物，其包含约5至约85重量％的R-1234ze（E），约2至约20重量％的R-152a和约5至约60重量％的1,1 ，1,2-四氟乙烷（R-1​​34a）。

公开(公告)号：EP2388002A2

公开(公告)日：2011-11-23

申请号：EP11006539.8

申请日：2007-10-15

申请人： ZENYAKU KOGYO KABUSHIKIKAISHA

发明人： Yamaguchi, Yoshimasa ,  Yui, Ryogo ,  Matsuno, Toshiyuki ,  Saitoh, Kenichi ,  Miyashita, Hitoshi ,  Nagata, Takeshi

IPC分类号： A61K31/429 ,  A61K31/437 ,  A61K31/438 ,  A61K31/519 ,  A61P25/24 ,  C07D471/04 ,  C07D471/10 ,  C07D487/04 ,  C07D513/04 ,  C07D487/10 ,  C07D513/20

CPC分类号： A61K31/437 ,  A61K31/40 ,  A61K31/4015 ,  A61K31/425 ,  A61K31/426 ,  A61K31/429 ,  A61K31/438 ,  A61K31/444 ,  A61K31/4745 ,  A61K31/495 ,  A61K31/519 ,  C07D471/04 ,  C07D471/10 ,  C07D487/04 ,  C07D487/10 ,  C07D513/04 ,  C07D513/20

摘要： Disclosed is an antidepressant composition containing a heterocyclic compound having the general formula (I).

摘要翻译： 公开的是含有具有通式（I）的杂环化合物的抗抑郁组合物。

公开(公告)号：EP2371818A1

公开(公告)日：2011-10-05

申请号：EP11002581.4

申请日：2005-11-09

申请人： Targacept, Inc.

发明人： Munoz, Julio A. ,  Genus, John ,  Moore, James R.

IPC分类号： C07D213/65 ,  A61K31/44 ,  A61P25/00

CPC分类号： C07D213/38 ,  C07D213/65 ,  C07D213/73 ,  C07D213/75 ,  C07D401/12

摘要： (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridinyl)-4-penten-2-amine p -hydroxybenzoate and a pharmaceutical composition comprising this compound.

摘要翻译： （2S） - （4E）-N-甲基-5-（5-异丙氧基-3-吡啶基）-4-戊烯-2-胺对羟基苯甲酸酯和包含该化合物的药物组合物。

公开(公告)号：EP2361076A1

公开(公告)日：2011-08-31

申请号：EP09764140.1

申请日：2009-11-24

申请人： Baxter International Inc. ,  Baxter Healthcare SA

发明人： SMITH, Donald, A. ,  JEPSON, Steven, C. ,  DUDAR, Thomas, E.

IPC分类号： A61J1/20

CPC分类号： A61J1/2096 ,  A61J1/201 ,  A61J1/2055

摘要： A spike assembly having an elongate spike defining a hollow cannula that is in fluid communication with the interior of a liter connection portion. The spike assembly provides needleless access to a stopper of a vial to facilitate injection and withdrawal of fluids via a syringe barrel selectively secured to the luer connection portion. The syringe can safely be removed from the spike assembly and then be directly attached to a luer compatible connector. The elongate spike may include a frangible tip portion that can break away from the spike assembly within a vial. The spike assembly may have a neck with a pair of gripping wing members. The spike assembly may have a feature that prevents rotation of the spike in the vial stopper, thereby allowing the syringe to be easily and safely disconnected from the spike assembly without having to grasp the spike assembly.

公开(公告)号：EP2322236A1

公开(公告)日：2011-05-18

申请号：EP10075490.2

申请日：2002-11-04

申请人： Baxter International Inc

发明人： Elisabettini, Paola ,  Menneguerre, Jean-Paul ,  Colas, Jerome ,  Renaux, Christian ,  Divino, Jose ,  Faict, Dirk ,  Wilmet, Isabelle

IPC分类号： A61M1/28 ,  A61K33/14 ,  A61P13/12

CPC分类号： A61K33/14

摘要： Bicarbonate containing solutions for use during medical treatment are provided. The bicarbonate containing solution of the present invention includes at least two separate components including a bicarbonate concentrate and an electrolyte concentrate which can be readily and sterilely mixed to form a ready-to-use formulation for patient administration, particularly as applied to the treatment of acute renal failure associated with critically ill patients in an intensive care setting.

摘要翻译： 提供了在医疗中使用的含碳酸氢盐溶液。 本发明的含碳酸氢盐溶液包括至少两种分离的组分，包括碳酸氢盐浓缩物和电解质浓缩物，其可以容易地和无菌地混合以形成用于患者给药的即用型制剂，特别是用于治疗急性 重症监护病房与危重病人相关的肾衰竭。