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11.发明公开
公开(公告)号：EP4370126A1
公开(公告)日：2024-05-22
申请号：EP22843071.6
申请日：2022-07-15
发明人： VERANO, Alyssa , WANG, Eric , YOU, Inchul , GRAY, Nathanael
IPC分类号： A61K31/519 , C07D471/04 , C07D487/04
CPC分类号： C07D471/04 , A61K47/545 , A61K47/55
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公开(公告)号：EP4324518A3
公开(公告)日：2024-05-22
申请号：EP23203095.7
申请日：2015-01-30
发明人： SABATOS-PEYTON, Catherine, Anne , BRANNETTI, Barbara , HARRIS, Alan, S. , HUBER, Thomas , PIETZONKA, Thomas , MATARAZA, Jennifer, Marie , BLATTLER, Walter, A. , HICKLIN, Daniel, J. , VASQUEZ, Maximiliano , DEKRUYFF, Rosemarie, H. , UMETSU, Dale, T. , FREEMAN, Gordon, James , HU, Tiancen , TARASZKA, John, A. , XU, Fangmin
IPC分类号： C07K16/28 , A61K39/395 , G01N33/68 , A61P1/04 , A61P1/16 , A61P1/18 , A61P7/00 , A61P11/00 , A61P13/08 , A61P15/00 , A61P17/00 , A61P25/00 , A61P31/00 , G01N33/574 , A61P13/12 , A61P35/00 , A61P37/02 , A61P35/02 , A61P35/04 , A61P37/04
CPC分类号： C07K2299/0020130101 , C07K2317/3420130101 , C07K2317/7620130101 , C07K2317/9420130101 , A61K39/395 , G01N33/57492 , G01N2333/7059620130101 , C07K16/2803 , C07K2317/2420130101 , A61P1/04 , A61P1/16 , A61P1/18 , A61P11/00 , A61P13/08 , A61P13/12 , A61P15/00 , A61P17/00 , A61P25/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P35/04 , A61P37/02 , A61P37/04 , A61P7/00 , Y02A50/30 , C07K2317/9220130101
摘要： Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
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公开(公告)号：EP4363412A1
公开(公告)日：2024-05-08
申请号：EP22834157.4
申请日：2022-06-29
发明人： CHE, Jianwei , DU, Guangyan , ZHANG, Tinghu , JI, Wenzhi
IPC分类号： C07D401/14 , C07D413/14 , C07D417/14 , A61P35/00
CPC分类号： A61P35/00 , C07D519/00 , C07D487/08
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公开(公告)号：EP4341254A1
公开(公告)日：2024-03-27
申请号：EP22805453.2
申请日：2022-05-19
发明人： GRAY, Nathanael S. , TENG, Mingxing , WANG, Eric , JIANG, Jie , ZHANG, Tinghu , CANTLEY, Lewis C. , FISCHER, Eric S. , DONOVAN, Katherine A.
IPC分类号： C07D403/12 , C07D403/14 , C07D417/14
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公开(公告)号：EP4319800A1
公开(公告)日：2024-02-14
申请号：EP22721536.5
申请日：2022-04-07
申请人： Dana-Farber Cancer Institute, Inc. , Beth Israel Deaconess Medical Center , Avigan, David , Rosenblatt, Jacalyn , Stroopinsky, Dina
IPC分类号： A61K39/00 , A61P35/02 , A61K31/635 , A61K31/706
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公开(公告)号：EP4292657A2
公开(公告)日：2023-12-20
申请号：EP23181586.1
申请日：2014-03-14
发明人： MARASCO, Wayne, A.
IPC分类号： A61P31/14
摘要： The present invention provides antibodies that neutralize flavivirus and methods of use thereof. These antibodies are derived from mAbl I which recognizes West Nile virus E protein and is cross-reactive with members of the flavivirus family, including Denge virus. The antibodies of the present invention prevent antibody-dependent enhancement of a viral infection by having a modified Fc region that does not bind to the Fcy receptor. The invented antibody is used to treat flaviviral infections and symptoms thereof.
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公开(公告)号：EP4263874A1
公开(公告)日：2023-10-25
申请号：EP21907957.1
申请日：2021-12-17
申请人： President and Fellows of Harvard College , Dana-Farber Cancer Institute, Inc. , Shi, Jiantao , Smith, Zachary, D. , Meissner, Alexander , Michor, Franziska
IPC分类号： C12Q1/6886 , G16B20/10 , G16B20/20
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公开(公告)号：EP4259820A1
公开(公告)日：2023-10-18
申请号：EP21904530.9
申请日：2021-12-10
IPC分类号： C12Q1/68 , C12Q1/6869 , G16B30/20
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公开(公告)号：EP4245376A2
公开(公告)日：2023-09-20
申请号：EP23169814.3
申请日：2015-10-13
发明人： FREEMAN, Gordon, James , SHARPE, Arlene, Helen , FREY, Gerhard, Johann , CHANG, Hwai, Wen , MATARAZA, Jennifer, Marie , DRANOFF, Glenn
IPC分类号： A61P37/02
摘要： Antibody molecules that specifically bind to PD-L1 are disclosed. Combination therapies comprising the anti-PD-L1 antibody molecules are also disclosed. The anti-PD-L1 antibody molecules can be used to treat, prevent and/or diagnose cancerous or infectious conditions and disorders.
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公开(公告)号：EP4225300A1
公开(公告)日：2023-08-16
申请号：EP21878296.9
申请日：2021-10-04
IPC分类号： A61K31/40 , A61K31/4025 , A61K31/519 , C07D207/04 , C07D487/00 , C07D487/04
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