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公开(公告)号：EP3878465A1
公开(公告)日：2021-09-15
申请号：EP21152298.2
申请日：2016-07-28
发明人： DRANOFF, Glenn , SABATOS-PEYTON, Catherine, Anne , BRANNETTI, Barbara , HARRIS, Alan, S. , HUBER, Thomas , PIETZONKA, Thomas , MATARAZA, Jennifer, Marie , BLATTLER, Walter, A. , HICKLIN, Daniel, J. , VASQUEZ, Maximiliano , DEKRUYFF, Rosemarie, H. , UMETSU, Dale, T. , FREEMAN, Gordon, James , HU, Tiancen , TARASZKA, John, A. , XU, Fangmin
摘要： Combination therapies comprising antibody molecules that specifically bind to TIM-3 are disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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公开(公告)号：EP4324518A3
公开(公告)日：2024-05-22
申请号：EP23203095.7
申请日：2015-01-30
发明人： SABATOS-PEYTON, Catherine, Anne , BRANNETTI, Barbara , HARRIS, Alan, S. , HUBER, Thomas , PIETZONKA, Thomas , MATARAZA, Jennifer, Marie , BLATTLER, Walter, A. , HICKLIN, Daniel, J. , VASQUEZ, Maximiliano , DEKRUYFF, Rosemarie, H. , UMETSU, Dale, T. , FREEMAN, Gordon, James , HU, Tiancen , TARASZKA, John, A. , XU, Fangmin
IPC分类号： C07K16/28 , A61K39/395 , G01N33/68 , A61P1/04 , A61P1/16 , A61P1/18 , A61P7/00 , A61P11/00 , A61P13/08 , A61P15/00 , A61P17/00 , A61P25/00 , A61P31/00 , G01N33/574 , A61P13/12 , A61P35/00 , A61P37/02 , A61P35/02 , A61P35/04 , A61P37/04
CPC分类号： C07K2299/0020130101 , C07K2317/3420130101 , C07K2317/7620130101 , C07K2317/9420130101 , A61K39/395 , G01N33/57492 , G01N2333/7059620130101 , C07K16/2803 , C07K2317/2420130101 , A61P1/04 , A61P1/16 , A61P1/18 , A61P11/00 , A61P13/08 , A61P13/12 , A61P15/00 , A61P17/00 , A61P25/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P35/04 , A61P37/02 , A61P37/04 , A61P7/00 , Y02A50/30 , C07K2317/9220130101
摘要： Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
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公开(公告)号：EP3099717B1
公开(公告)日：2019-03-27
申请号：EP15705163.2
申请日：2015-01-30
发明人： SABATOS-PEYTON, Catherine, Anne , BRANNETTI, Barbara , HARRIS, Alan, S. , HUBER, Thomas , PIETZONKA, Thomas , MATARAZA, Jennifer, Marie , BLATTLER, Walter, A. , HICKLIN, Daniel, J. , VASQUEZ, Maximiliano , DEKRUYFF, Rosemarie, H. , UMETSU, Dale, T. , FREEMAN, Gordon, James , HU, Tiancen , TARASZKA, John, A. , XU, Fangmin
IPC分类号： C07K16/28 , A61K39/395 , A61K45/06 , G01N33/68
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公开(公告)号：EP4324518A2
公开(公告)日：2024-02-21
申请号：EP23203095.7
申请日：2015-01-30
发明人： SABATOS-PEYTON, Catherine, Anne , BRANNETTI, Barbara , HARRIS, Alan, S. , HUBER, Thomas , PIETZONKA, Thomas , MATARAZA, Jennifer, Marie , BLATTLER, Walter, A. , HICKLIN, Daniel, J. , VASQUEZ, Maximiliano , DEKRUYFF, Rosemarie, H. , UMETSU, Dale, T. , FREEMAN, Gordon, James , HU, Tiancen , TARASZKA, John, A. , XU, Fangmin
IPC分类号： A61P1/18
摘要： Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
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公开(公告)号：EP3316902A1
公开(公告)日：2018-05-09
申请号：EP16750331.7
申请日：2016-07-28
发明人： DRANOFF, Glenn , SABATOS-PEYTON, Catherine, Anne , BRANNETTI, Barbara , HARRIS, Alan, S. , HUBER, Thomas , PIETZONKA, Thomas , MATARAZA, Jennifer, Marie , BLATTLER, Walter, A. , HICKLIN, Daniel, J. , VASQUEZ, Maximiliano , DEKRUYFF, Rosemarie, H. , UMETSU, Dale, T. , FREEMAN, Gordon, James , HU, Tiancen , TARASZKA, John, A. , XU, Fangmin
CPC分类号： A61K39/39566 , A61K39/00 , A61K39/3955 , A61K45/06 , A61K2039/507 , A61P35/00 , C07K16/2803 , C07K2299/00 , C07K2317/24 , C07K2317/34 , C07K2317/76 , C07K2317/94 , A61K2300/00
摘要： Combination therapies comprising antibody molecules that specifically bind to TIM-3 are disclosed. The combination therapies can be used to treat or prevent cancerous or infectious conditions and disorders.
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6.发明公开ANTIBODY MOLECULES TO TIM-3 AND USES THEREOF 审中-公开ANTIKÖRPERMOLEKÜLEMIT TIM-3 UND VERWENDUNGEN DAVON
公开(公告)号：EP3099717A1
公开(公告)日：2016-12-07
申请号：EP15705163.2
申请日：2015-01-30
发明人： SABATOS-PEYTON, Catherine, Anne , BRANNETTI, Barbara , HARRIS, Alan, S. , HUBER, Thomas , PIETZONKA, Thomas , MATARAZA, Jennifer, Marie , BLATTLER, Walter, A. , HICKLIN, Daniel, J. , VASQUEZ, Maximiliano , DEKRUYFF, Rosemarie, H. , UMETSU, Dale, T. , FREEMAN, Gordon, James , HU, Tiancen , TARASZKA, John, A. , XU, Fangmin
IPC分类号： C07K16/28
CPC分类号： C07K16/2803 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K2299/00 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , G01N33/6893
摘要： Antibody molecules that specifically bind to TIM-3 are disclosed. The anti-TIM-3 antibody molecules can be used to treat, prevent and/or diagnose immune, cancerous, or infectious conditions and/or disorders.
摘要翻译： 公开了特异性结合TIM-3的抗体分子。 抗TIM-3抗体分子可用于治疗，预防和/或诊断免疫，癌性或感染性疾病和/或病症。
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公开(公告)号：EP2931317A2
公开(公告)日：2015-10-21
申请号：EP13862109.9
申请日：2013-12-12
发明人： CHOE, Hyeryun , JEMIELITY, Stephanie , UMETSU, Dale, T. , DE KRUYFF, Rosemarie, Helena , FREEMAN, Gordon
IPC分类号： A61K48/00 , A61K39/395 , A61P31/12 , A61P31/00
CPC分类号： A61K38/1774 , A61K31/685 , A61K31/7105 , A61K31/713 , A61K45/00 , C07K14/70503 , C07K16/2803 , C07K2317/76 , C07K2319/30 , C12N15/113 , C12N15/1138 , C12N2310/11 , C12N2310/14 , C12N2310/17 , C12N2310/531
摘要： The invention provides methods, compositions, and kits featuring agents that inhibit viral entry mediated by T-cell Immunoglobulin and Mucin-domain containing proteins (TIM proteins) and other phosphatidylserine receptors.
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8.发明公开INHIBITION OF VIRAL INFECTION-TRIGGERED ASTHMA WITH C-KIT INHIBITOR 审中-公开病毒INFEKTIONSAUSGELÖSTEM哮喘的抑制与C-KIT抑制剂
公开(公告)号：EP2895170A1
公开(公告)日：2015-07-22
申请号：EP13836850.1
申请日：2013-09-13
IPC分类号： A61K31/496 , A61K31/506 , A61P11/00
CPC分类号： A61K31/506 , A61K31/4439 , A61K31/496 , A61K39/3955 , A61K45/06 , C07K14/71 , C07K16/2866 , C07K2317/76 , C12N2760/16111 , C12N2760/18511 , A61K2300/00
摘要： The invention provides methods, compositions, and kits featuring a c-Kit kinase inhibitor for use in preventing or treating virus-induced respiratory pathology.
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