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公开(公告)号:EP4319800A1
公开(公告)日:2024-02-14
申请号:EP22721536.5
申请日:2022-04-07
申请人: Dana-Farber Cancer Institute, Inc. , Beth Israel Deaconess Medical Center , Avigan, David , Rosenblatt, Jacalyn , Stroopinsky, Dina
IPC分类号: A61K39/00 , A61P35/02 , A61K31/635 , A61K31/706
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2.STIMULATION OF ANTI-TUMOR IMMUNITY USING DENDRITIC CELL/TUMOR CELL FUSIONS AND ANTI-CD3/CD28 有权
标题翻译: 起搏肿瘤免疫使用细胞兼并OFF树突细胞和肿瘤细胞和抗CD3 / CD28抗体公开(公告)号:EP2215220A1
公开(公告)日:2010-08-11
申请号:EP08846621.4
申请日:2008-11-07
发明人: AVIGAN, David , KUFE, Donald
CPC分类号: A61K39/0011 , A61K2039/5154 , A61K2039/5158 , A61K2039/55538 , C12N5/0636 , C12N5/16 , C12N2501/056 , C12N2501/23 , C12N2501/51 , C12N2501/515
摘要: The invention is concerned with fusions of dendritic cells and with tumor or cancer cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy as well as methods of stimulating anti-tumor immunity using fused cells and anti-CD3/CD28 antibodies.
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公开(公告)号:EP3277323A1
公开(公告)日:2018-02-07
申请号:EP16718547.9
申请日:2016-03-30
发明人: AVIGAN, David , ROSENBLATT, Jacalyn , KUFE, Donald
IPC分类号: A61K45/06 , A61K35/15 , A61K31/4035 , A61K31/454 , C12N5/12 , A61P35/00
CPC分类号: A61K31/4035 , A61K31/09 , A61K31/454 , A61K35/15 , A61K45/06 , A61K2300/00 , C12N5/0639 , C12N5/0693 , C12N5/12
摘要: The present invention provides compositions and methods for treating cancer.
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公开(公告)号:EP3436057A1
公开(公告)日:2019-02-06
申请号:EP17720591.1
申请日:2017-03-30
发明人: KUFE, Donald , AVIGAN, David
IPC分类号: A61K39/00 , C12N5/0784 , C12N5/16
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公开(公告)号:EP3377087A1
公开(公告)日:2018-09-26
申请号:EP16816786.4
申请日:2016-11-21
发明人: AVIGAN, David , ROSENBLATT, Jacalyn , KUFE, Donald
CPC分类号: A61K38/1709
摘要: The present invention provides compositions and methods for treating cancer.
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公开(公告)号:EP3277292A1
公开(公告)日:2018-02-07
申请号:EP16718546.1
申请日:2016-03-30
发明人: AVIGAN, David , ROSENBLATT, Jacalyn , KUFE, Donald
CPC分类号: A61K35/15 , A61K38/193 , A61K45/06
摘要: The present invention provides compositions and methods for treating multiple myeloma.
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公开(公告)号:EP3277291A1
公开(公告)日:2018-02-07
申请号:EP16718545.3
申请日:2016-03-30
发明人: AVIGAN, David , ROSENBLATT, Jacalyn , KUFE, Donald
CPC分类号: A61K35/15
摘要: The present invention provides compositions and methods for treating acute myeloid leukemia.
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8.
公开(公告)号:EP3375868A1
公开(公告)日:2018-09-19
申请号:EP18150910.0
申请日:2008-11-07
发明人: AVIGAN, David , KUFE, Donald
CPC分类号: A61K39/0011 , A61K2039/5154 , A61K2039/5158 , A61K2039/55538 , C12N5/0636 , C12N5/16 , C12N2501/056 , C12N2501/23 , C12N2501/51 , C12N2501/515
摘要: The invention is concerned with fusions of dendritic cells and with tumor or cancer cells. Also provided are methods of making and using these cell fusions, including methods of adoptive immunotherapy as well as methods of stimulating anti-tumor immunity using fused cells and anti-CD3/CD28 antibodies.
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公开(公告)号:EP3277322A1
公开(公告)日:2018-02-07
申请号:EP16715741.1
申请日:2016-03-30
发明人: AVIGAN, David , ROSENBLATT, Jacalyn , KUFE, Donald
IPC分类号: A61K45/06 , A61K35/15 , A61P35/00 , A61K31/4035 , A61K31/454 , C12N5/12
CPC分类号: A61K35/15 , A61K31/4035 , A61K31/454 , A61K45/06 , A61K2300/00 , C12N5/12 , C12N2501/22 , C12N2502/1121 , C12N2502/30
摘要: The present invention provides compositions and methods for treating cancer.
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公开(公告)号:EP3277290A1
公开(公告)日:2018-02-07
申请号:EP16718544.6
申请日:2016-03-30
发明人: AVIGAN, David , ROSENBLATT, Jacalyn , KUFE, Donald
CPC分类号: A61K39/0011 , A61K35/15 , A61K38/193 , A61K39/3955 , A61K45/06 , A61K2039/5154 , A61K2039/575 , C07K16/2803 , C07K16/2818 , C07K16/2827 , C12N15/02 , C12N2501/22 , C12N2502/1121 , C12N2502/30
摘要: The present invention provides compositions and methods for treating renal cell carcinoma
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