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    APPARATUS AND METHODS FOR DETECTING OPTICAL SIGNALS FROM IMPLANTED SENSORS
    18.
    发明公开
    APPARATUS AND METHODS FOR DETECTING OPTICAL SIGNALS FROM IMPLANTED SENSORS 审中-公开
    DEVICE AND METHOD FOR光信号从注入传感器的检测

    公开(公告)号：EP3003131A2

    公开(公告)日：2016-04-13

    申请号：EP14807637.5

    申请日：2014-06-06

    申请人： Profusa, Inc.

    发明人： KINTZ, Gregory J. ,  MCMILLAN, William A. ,  WISNIEWSKI, Natalie A.

    IPC分类号： A61B5/00

    摘要： Some embodiments described herein relate to an apparatus including a light source configured to transmit an excitation optical signal to an implanted sensor and a detector configured to detect an analyte-dependent optical signal emitted from an implanted sensor. The apparatus can include a lens configured to focus at least a portion of the analyte-dependent optical signal onto the detector.

    摘要翻译： 一些实施例涉及在对设备包括：光源发送被设定为在植入的传感器和检测器的光信号激励至以检测被配置为从到植入的传感器发射分析物相关的光信号进行说明。 该装置可以包括配置成聚焦至少所述分析物相关的光学信号的一部分到检测器上的透镜。

    METHOD AND SYSTEM FOR DIRECTING A LOCALIZED BIOLOGICAL RESPONSE TO AN IMPLANT
    19.
    发明公开
    METHOD AND SYSTEM FOR DIRECTING A LOCALIZED BIOLOGICAL RESPONSE TO AN IMPLANT 审中-公开
    方法和系统用于创建局部生物响应的植入

    公开(公告)号：EP2437846A2

    公开(公告)日：2012-04-11

    申请号：EP10783874.0

    申请日：2010-05-28

    申请人： Profusa, Inc.

    发明人： MCMILLAN, William, A. ,  WISNIEWSKI, Natalie

    IPC分类号： A61M37/00 ,  A61M5/14 ,  A61M35/00

    CPC分类号： A61N5/062 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1459 ,  A61K9/0024 ,  A61K9/7038 ,  A61M5/14276 ,  A61M11/00 ,  A61M35/00 ,  A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0061 ,  A61M2205/52 ,  A61M2205/587 ,  A61M2230/005 ,  A61M2230/201 ,  A61N2005/0626 ,  A61N2005/0645 ,  A61N2005/0652 ,  A61N2005/0661 ,  A61N2005/067

    摘要： The invention provides methods for directing a localized biological response of a mammalian body to an implant disposed within the body. In one embodiment, a delivery system is positioned outside the body and adjacent to the implant within the body. The delivery system comprises a first tissue response modifier effective for directing a localized biological response of the body to the implant. The tissue response modifier is nonsurgically delivered from the delivery system into the body in a quantity effective to direct the localized biological response of the body to the implant. The invention also provides an implant system for long-term use comprising an implant and nonsurgical means for delivering a tissue response modifier through the epidermis of the body, the tissue response modifier effective for directing a localized biological response of the body to the implant.

    摘要翻译： 本发明提供用于引导哺乳动物机体的在植入物主体内设置的局部生物应答的方法。 在一个中，递送系统实施例的位于主体外部并靠近所述主体内的植入物。 该递送系统包括第一组织响应调节剂有效引导所述本体的所述植入物的局部生物响应。 所述组织响应调节剂非手术从递送系统递送到体内以有效引导主体的所述植入物的局部生物反应的量。 因此本发明提供了植入物系统，为长期使用，用于通过所述主体中，所述组织响应调节剂有效引导所述本体的所述植入物的局部生物响应的表皮递送组织响应调节剂，包括植入物和非手术手段。