-
11.发明公开
公开(公告)号：EP2621526A1
公开(公告)日：2013-08-07
申请号：EP11831345.1
申请日：2011-09-29
发明人： SATPAEV, Daulet , MORRISON, Robert, Kendall , MORRISON, Karen Jane, Meyrick , GUDAS, Jean , JAKOBOVITS, Aya , TORGOV, Michael , AN, Zili
IPC分类号： A61K39/00 , A61K39/395 , C07K1/00
CPC分类号： A61K47/6851 , A61K47/6801 , A61K47/6803 , A61K47/6811 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6889 , A61K2039/505 , A61N5/1001 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K2317/14 , C07K2317/34 , C07K2317/565 , C07K2317/73 , C07K2317/92
摘要： Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
-
公开(公告)号：EP2621526B1
公开(公告)日：2018-06-06
申请号：EP11831345.1
申请日：2011-09-29
发明人： SATPAEV, Daulet , MORRISON, Robert, Kendall , MORRISON, Karen Jane, Meyrick , GUDAS, Jean , JAKOBOVITS, Aya , TORGOV, Michael , AN, Zili
CPC分类号： A61K47/48569 , A61K47/48384 , A61K47/48415 , A61K47/6801 , A61K47/6803 , A61K47/6811 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6859 , A61K47/6861 , A61K47/6889 , A61K2039/505 , A61N5/1001 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K2317/14 , C07K2317/34 , C07K2317/565 , C07K2317/73 , C07K2317/92
摘要： Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
-
公开(公告)号：EP1753871B1
公开(公告)日：2015-07-15
申请号：EP05752076.9
申请日：2005-05-17
申请人： Agensys, Inc.
发明人： GUDAS, Jean , JAKOBOVITS, Aya , JIA, Xiao-chi , MORRISON, Robert, Kendall , MORRISON, Karen, Jane, Meyrick , SHAO, Hui , CHALLITA-EID, Pia, M. , RAITANO, Arthur, B.
CPC分类号： C07K14/705 , A61K39/00 , A61K49/0002 , A61K2039/505 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/734 , C07K2317/77
-
14.发明授权ANTIBODIES AND MOLECULES DERIVED THEREFROM THAT BIND TO STEAP-1 PROTEINS 有权抗体和它们的衍生物分子是否涉及STEAP-1蛋白结合
公开(公告)号：EP1742966B1
公开(公告)日：2013-11-27
申请号：EP04750565.6
申请日：2004-04-22
申请人： Agensys, Inc.
发明人： JAKOBOVITS, Aya , ETESSAMI, Soudabeh , CHALLITA-EID, Pia, M. , PEREZ-VILLAR, Juan, J. , MORRISON, Karen, J. , JIA, Xiao-Chi , FARIS, Mary , GUDAS, Jean , RAITANO, Arthur, B.
IPC分类号： C07K16/30 , A61K39/395
CPC分类号： C07K16/40 , A61K39/39533 , A61K45/06 , A61K47/48607 , A61K47/6861 , A61K51/106 , A61K51/1075 , A61K2039/505 , C07H21/04 , C07K16/3069 , C07K2317/24 , C07K2317/565 , G01N33/6887 , A61K2300/00
摘要： Antibodies and molecules derived therefrom that bind to novel STEAP-1 protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The STEAP-1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with STEAP-1 can be used in active or passive immunization.
-
公开(公告)号：EP2185574B1
公开(公告)日：2013-05-08
申请号：EP08799268.1
申请日：2008-09-05
申请人： Agensys, Inc.
发明人： RAITANO, Arthur, B. , MORRISON, Robert, Rendall , MORRISON, Karen Jane, Mayrick , KANMER, Steven, B. , CHALLITA-EID, Pia, M. , JIA, Xiao-chi , GUDAS, Jean , JAKOBOVITS, Aya
IPC分类号： C07K16/30 , C07H21/02 , A61K31/713 , G01N33/574
CPC分类号： G01N33/57484 , A01K2267/0331 , A61K51/1045 , C07K16/30 , C07K16/3015 , C07K16/303 , C07K16/3046 , C07K2317/56 , C07K2317/732 , C07K2317/77 , G01N2500/00
-
公开(公告)号：EP1753871A2
公开(公告)日：2007-02-21
申请号：EP05752076.9
申请日：2005-05-17
申请人： Agensys, Inc.
发明人： GUDAS, Jean , JAKOBOVITS, Aya , JIA, Xiao-chi , MORRISON, Robert, Kendall , MORRISON, Karen, Jane, Meyrick , SHAO, Hui , CHALLITA-EID, Pia, M. , RAITANO, Arthur, B.
CPC分类号： C07K14/705 , A61K39/00 , A61K49/0002 , A61K2039/505 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/734 , C07K2317/77
摘要： Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
-
17.发明公开NUCLEIC ACID AND CORRESPONDING PROTEIN NAMED 158P1D7 USEFUL IN THE TREATMENT AND DETECTION OF BLADDER AND OTHER CANCERS 审中-公开NUCLEIC和用于治疗和检测膀胱癌和其他癌症与名称158P1D7相应的蛋白质适合...
公开(公告)号：EP1594892A2
公开(公告)日：2005-11-16
申请号：EP04709923.9
申请日：2004-02-10
申请人： Agensys, Inc.
发明人： JAKOBOVITS, Aya , MORRISON, Robert, Kendall , RAITANO, Arthur, B. , CHALLITA-EID, Pia, M. , PEREZ-VILLAR, Juan, J. , MORRISON, Karen, Jane, Meyrick , FARIS, Mary , GE, Wangmao , GUDAS, Jean , KANNER, Steven, B.
IPC分类号： C07K14/47
摘要： A novel gene (designated 158P1D7) and its encoded protein are described. While 158P1D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 158P1D7 provides a diagnostic and/or therapeutic target for cancers. The 158P1D7 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.
-
-
-
-
-
-
搜索结果
17 条记录 (耗时 0.056 秒)
